DE3870183D1 - Verfahren zur herstellung von n-(2-chlorobenzyl)(2-thienyl)-2-ethylamin. - Google Patents
Verfahren zur herstellung von n-(2-chlorobenzyl)(2-thienyl)-2-ethylamin.Info
- Publication number
- DE3870183D1 DE3870183D1 DE8888403198T DE3870183T DE3870183D1 DE 3870183 D1 DE3870183 D1 DE 3870183D1 DE 8888403198 T DE8888403198 T DE 8888403198T DE 3870183 T DE3870183 T DE 3870183T DE 3870183 D1 DE3870183 D1 DE 3870183D1
- Authority
- DE
- Germany
- Prior art keywords
- chlorobenzyl
- ethylamine
- thienyl
- producing
- chlorobenzylamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- NJIDCUIBKZTRAD-UHFFFAOYSA-N n-[(2-chlorophenyl)methyl]-n-ethylthiophen-2-amine Chemical compound C=1C=CSC=1N(CC)CC1=CC=CC=C1Cl NJIDCUIBKZTRAD-UHFFFAOYSA-N 0.000 title 1
- KDDNKZCVYQDGKE-UHFFFAOYSA-N (2-chlorophenyl)methanamine Chemical compound NCC1=CC=CC=C1Cl KDDNKZCVYQDGKE-UHFFFAOYSA-N 0.000 abstract 1
- CLSHQIDDCJTHAJ-UHFFFAOYSA-N 2-thienylacetonitrile Chemical compound N#CCC1=CC=CS1 CLSHQIDDCJTHAJ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8717755A FR2624860B1 (fr) | 1987-12-18 | 1987-12-18 | Procede de preparation de la n-(chloro-2 benzyl) (thienyl-2)-2 ethylamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3870183D1 true DE3870183D1 (de) | 1992-05-21 |
Family
ID=9358062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8888403198T Expired - Lifetime DE3870183D1 (de) | 1987-12-18 | 1988-12-15 | Verfahren zur herstellung von n-(2-chlorobenzyl)(2-thienyl)-2-ethylamin. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4873343A (de) |
| EP (1) | EP0321349B1 (de) |
| JP (1) | JP2664450B2 (de) |
| KR (1) | KR960014798B1 (de) |
| AT (1) | ATE74918T1 (de) |
| CA (1) | CA1329212C (de) |
| DE (1) | DE3870183D1 (de) |
| ES (1) | ES2032218T3 (de) |
| FR (1) | FR2624860B1 (de) |
| PT (1) | PT89228B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2664596B1 (fr) * | 1990-07-10 | 1994-06-10 | Sanofi Sa | Procede de preparation d'un derive n-phenylacetique de tetrahydrothieno [3,2-c] pyridine et son intermediaire de synthese. |
| US6043368A (en) * | 1996-09-04 | 2000-03-28 | Poli Industria Chimica, S.P.A. | Method of making thieno-pyridine derivatives |
| FR2760456B1 (fr) * | 1997-03-05 | 2000-05-12 | Sanofi Sa | Procede de preparation de derives de 2-thienyl-ethylamine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2300090A1 (fr) * | 1975-02-07 | 1976-09-03 | Parcor | Procede de preparation de derives de la thienopyridine |
| FR2508455A1 (fr) * | 1981-06-30 | 1982-12-31 | Sanofi Sa | Procede de preparation de derives des (thienyl-2)- et (thienyl-3)-2 ethylamines |
| FR2608607B1 (fr) * | 1986-12-23 | 1989-04-28 | Sanofi Sa | Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues |
-
1987
- 1987-12-18 FR FR8717755A patent/FR2624860B1/fr not_active Expired - Fee Related
-
1988
- 1988-11-23 US US07/275,369 patent/US4873343A/en not_active Expired - Lifetime
- 1988-12-05 CA CA000584974A patent/CA1329212C/en not_active Expired - Lifetime
- 1988-12-08 KR KR88016378A patent/KR960014798B1/ko not_active IP Right Cessation
- 1988-12-15 PT PT89228A patent/PT89228B/pt not_active IP Right Cessation
- 1988-12-15 EP EP88403198A patent/EP0321349B1/de not_active Expired - Lifetime
- 1988-12-15 AT AT88403198T patent/ATE74918T1/de not_active IP Right Cessation
- 1988-12-15 ES ES198888403198T patent/ES2032218T3/es not_active Expired - Lifetime
- 1988-12-15 JP JP63319325A patent/JP2664450B2/ja not_active Expired - Lifetime
- 1988-12-15 DE DE8888403198T patent/DE3870183D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR960014798B1 (en) | 1996-10-19 |
| PT89228A (pt) | 1989-12-29 |
| JP2664450B2 (ja) | 1997-10-15 |
| PT89228B (pt) | 1993-07-30 |
| JPH01197478A (ja) | 1989-08-09 |
| KR890009908A (ko) | 1989-08-04 |
| US4873343A (en) | 1989-10-10 |
| ES2032218T3 (es) | 1993-01-16 |
| ATE74918T1 (de) | 1992-05-15 |
| CA1329212C (en) | 1994-05-03 |
| EP0321349A1 (de) | 1989-06-21 |
| FR2624860A1 (fr) | 1989-06-23 |
| EP0321349B1 (de) | 1992-04-15 |
| FR2624860B1 (fr) | 1990-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: SANOFI-SYNTHELABO, PARIS, FR |
|
| 8328 | Change in the person/name/address of the agent |
Free format text: TER MEER STEINMEISTER & PARTNER GBR PATENTANWAELTE, 81679 MUENCHEN |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: SANOFI-AVENTIS, PARIS, FR |