DE3864124D1 - Isoxazole mit nootropischer wirkung. - Google Patents

Isoxazole mit nootropischer wirkung.

Info

Publication number
DE3864124D1
DE3864124D1 DE8888904406T DE3864124T DE3864124D1 DE 3864124 D1 DE3864124 D1 DE 3864124D1 DE 8888904406 T DE8888904406 T DE 8888904406T DE 3864124 T DE3864124 T DE 3864124T DE 3864124 D1 DE3864124 D1 DE 3864124D1
Authority
DE
Germany
Prior art keywords
pct
isoxazoles
nootropical
effect
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888904406T
Other languages
English (en)
Inventor
Angelo Carenzi
Dario Chiarino
Bella Davide Della
Mauro Napoletano
Alberto Sala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT20589/87A external-priority patent/IT1205014B/it
Priority claimed from IT20590/87A external-priority patent/IT1205015B/it
Application filed by Zambon SpA filed Critical Zambon SpA
Application granted granted Critical
Publication of DE3864124D1 publication Critical patent/DE3864124D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE8888904406T 1987-05-20 1988-05-19 Isoxazole mit nootropischer wirkung. Expired - Lifetime DE3864124D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT20589/87A IT1205014B (it) 1987-05-20 1987-05-20 Composti ad attivita' nootropa
IT20590/87A IT1205015B (it) 1987-05-20 1987-05-20 Composti ad attivita' nootropa
PCT/EP1988/000445 WO1988009330A1 (en) 1987-05-20 1988-05-19 Isoxazoles with nootropic activity

Publications (1)

Publication Number Publication Date
DE3864124D1 true DE3864124D1 (de) 1991-09-12

Family

ID=26327590

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888904406T Expired - Lifetime DE3864124D1 (de) 1987-05-20 1988-05-19 Isoxazole mit nootropischer wirkung.

Country Status (10)

Country Link
US (1) US4985428A (de)
EP (1) EP0317588B1 (de)
JP (1) JPH02500365A (de)
AT (1) ATE65997T1 (de)
AU (1) AU599809B2 (de)
DE (1) DE3864124D1 (de)
DK (1) DK4389A (de)
FI (1) FI89266C (de)
NO (1) NO172120C (de)
WO (1) WO1988009330A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0451790A1 (de) * 1990-04-12 1991-10-16 Hoechst Aktiengesellschaft 3,5-disubstituierte 2-Isoxazoline und Isoxazole, Verfahren zu deren Herstellung, diese enthaltende Mittel und ihre Verwendung
DE10105040A1 (de) * 2001-02-05 2002-08-14 Tell Pharm Ag Hergiswil Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
ITMI20042187A1 (it) 2004-11-16 2005-02-16 Zambon Spa Derivati isossazolici per allievare il dolore neiropatico

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2024M (fr) * 1961-02-01 1963-09-23 Shionogi & Co Utilisation de dérivés de l'isoxazole pour le traitement des maladies mentales et particulierement des dépressions nerveuses.
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel

Also Published As

Publication number Publication date
WO1988009330A1 (en) 1988-12-01
FI890173A (fi) 1989-01-13
DK4389D0 (da) 1989-01-06
AU599809B2 (en) 1990-07-26
NO172120B (no) 1993-03-01
FI89266C (fi) 1993-09-10
NO890245D0 (no) 1989-01-19
DK4389A (da) 1989-01-06
FI890173A0 (fi) 1989-01-13
ATE65997T1 (de) 1991-08-15
NO172120C (no) 1993-06-09
EP0317588A1 (de) 1989-05-31
FI89266B (fi) 1993-05-31
EP0317588B1 (de) 1991-08-07
US4985428A (en) 1991-01-15
NO890245L (no) 1989-01-19
AU1786988A (en) 1988-12-21
JPH02500365A (ja) 1990-02-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ZAMBON S.P.A., BRESSO, IT