DE3856351D1 - Verfahren zur immunologischen Bestimmung einer Komponente in einer Probe - Google Patents

Verfahren zur immunologischen Bestimmung einer Komponente in einer Probe

Info

Publication number
DE3856351D1
DE3856351D1 DE3856351T DE3856351T DE3856351D1 DE 3856351 D1 DE3856351 D1 DE 3856351D1 DE 3856351 T DE3856351 T DE 3856351T DE 3856351 T DE3856351 T DE 3856351T DE 3856351 D1 DE3856351 D1 DE 3856351D1
Authority
DE
Germany
Prior art keywords
monoclonal antibody
component
complex
fragment
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3856351T
Other languages
English (en)
Other versions
DE3856351T2 (de
Inventor
Johann Berger
Fern Delacroix
Harvey Buck
Juergen Schrenk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Operations Inc
Original Assignee
Boehringer Mannheim Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Corp filed Critical Boehringer Mannheim Corp
Publication of DE3856351D1 publication Critical patent/DE3856351D1/de
Application granted granted Critical
Publication of DE3856351T2 publication Critical patent/DE3856351T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/969—Multiple layering of reactants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Peptides Or Proteins (AREA)
DE3856351T 1988-01-21 1988-12-29 Verfahren zur immunologischen Bestimmung einer Komponente in einer Probe Expired - Lifetime DE3856351T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/146,574 US4891313A (en) 1988-01-21 1988-01-21 Method for determination of a component of a sample

Publications (2)

Publication Number Publication Date
DE3856351D1 true DE3856351D1 (de) 1999-08-26
DE3856351T2 DE3856351T2 (de) 2002-05-16

Family

ID=22518014

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3852040T Expired - Lifetime DE3852040T2 (de) 1988-01-21 1988-12-29 Vorrichtung und verfahren zur bestimmung einer komponente einer probe.
DE3856351T Expired - Lifetime DE3856351T2 (de) 1988-01-21 1988-12-29 Verfahren zur immunologischen Bestimmung einer Komponente in einer Probe

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3852040T Expired - Lifetime DE3852040T2 (de) 1988-01-21 1988-12-29 Vorrichtung und verfahren zur bestimmung einer komponente einer probe.

Country Status (8)

Country Link
US (1) US4891313A (de)
EP (2) EP0596867B1 (de)
JP (1) JP2694469B2 (de)
AT (1) ATE113722T1 (de)
CA (1) CA1336064C (de)
DE (2) DE3852040T2 (de)
ES (1) ES2138628T3 (de)
WO (1) WO1989006799A1 (de)

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US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US6861212B1 (en) 1987-11-18 2005-03-01 Chiron Corporation NANBV diagnostics and vaccines
US5714596A (en) * 1987-11-18 1998-02-03 Chiron Corporation NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus
US5712088A (en) * 1987-11-18 1998-01-27 Chiron Corporation Methods for detecting Hepatitis C virus using polynucleotides specific for same
US6171782B1 (en) 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
DE3814370A1 (de) * 1988-04-28 1989-11-09 Boehringer Mannheim Gmbh Testtraeger fuer die analyse einer probenfluessigkeit, verfahren zur durchfuehrung einer solchen analyse und herstellungsverfahren
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
DE3826057A1 (de) * 1988-07-30 1990-02-01 Boehringer Mannheim Gmbh Testtraeger zur analytischen bestimmung eines bestandteils einer fluessigen probe
US5338513A (en) * 1988-07-30 1994-08-16 Boehringer Mannheim Gmbh Test carrier for the analytical determination of a component of a liquid sample
US5079174A (en) * 1988-12-08 1992-01-07 Boehringer Mannheim Corporation Apparatus for sequential determination of an analyte in a fluid sample
DE3903114A1 (de) * 1989-02-02 1990-08-09 Boehringer Mannheim Gmbh Verfahren zur bestimmung eines enzyms aus einem isoenzymgemisch sowie hierfuer geeigneter testtraeger und dessen verwendung
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
GB8903627D0 (en) * 1989-02-17 1989-04-05 Unilever Plc Assays
US6027729A (en) * 1989-04-20 2000-02-22 Chiron Corporation NANBV Diagnostics and vaccines
DE4007836A1 (de) * 1989-11-14 1991-05-23 Boehringer Mannheim Gmbh Verfahren zur erhoehung der enzymatischen reaktivitaet von (beta)-galactosidase
US5620657A (en) * 1989-11-27 1997-04-15 Behringwerke Ag Device and method for completing a fluidic circuit
US5435970A (en) * 1989-12-18 1995-07-25 Environmental Diagnostics, Inc. Device for analysis for constituents in biological fluids
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
US5019521A (en) * 1990-03-12 1991-05-28 Photest Diagnostics, Inc. Paired polypeptides
DE4015378A1 (de) * 1990-05-14 1991-11-21 Boehringer Mannheim Gmbh Testtraeger fuer die analytische bestimmung eines bestandteils einer probenfluessigkeit
JP3193714B2 (ja) * 1991-02-27 2001-07-30 ロシュ ダイアグノスティックス コーポレーション 改良型テストストリップ
WO1992018865A1 (en) * 1991-04-11 1992-10-29 Cedars-Sinai Medical Center Immunoassay for the detection of hiv specific igm
US6664114B1 (en) * 1992-08-03 2003-12-16 Sapidyne Instruments, Inc. Solid phase assay for detection of ligands
US5958339A (en) * 1992-08-31 1999-09-28 Clinical Diagnostic Systems, Inc. Format for immunoassay in thin film
AT402674B (de) * 1993-01-18 1997-07-25 Waldheim Pharmazeutika Gmbh Verfahren und mittel zum nachweisen von verfahren und mittel zum nachweisen von antigenen antigenen
ATE213507T1 (de) * 1993-10-20 2002-03-15 Univ Duke Methode zur bindung von material an das beta- amyloid-peptid
GB9322650D0 (en) * 1993-11-03 1993-12-22 Cogent Diagnostics Ltd Analytical device
WO1995021190A1 (en) * 1994-02-07 1995-08-10 The United States Of America, Represented By The Secretary Of Agriculture Detection of wheat that has experienced elevated temperatures during the grain filling period
DE69616774T2 (de) * 1995-05-02 2002-09-05 Carter Wallace Verfahren zur herstellung eines laminierten substrats
US6319676B1 (en) 1995-05-02 2001-11-20 Carter Wallace, Inc. Diagnostic detection device and method
AU6248796A (en) * 1995-05-19 1996-11-29 Universal Health-Watch, Inc. Rapid self-contained assay format
AU6720096A (en) 1995-08-09 1997-03-05 Quidel Corporation Test strip and method for one step lateral flow assay
US6379909B1 (en) * 1998-06-24 2002-04-30 Alk-Abello A/S Method of detecting an antibody in a liquid sample
GB9923384D0 (en) * 1999-10-05 1999-12-08 Univ Birmingham Fluid-flow control device
US6436722B1 (en) * 2000-04-18 2002-08-20 Idexx Laboratories, Inc. Device and method for integrated diagnostics with multiple independent flow paths
US8323903B2 (en) 2001-10-12 2012-12-04 Life Technologies Corporation Antibody complexes and methods for immunolabeling
US20050069962A1 (en) 2001-10-12 2005-03-31 Archer Robert M Antibody complexes and methods for immunolabeling
US8315379B2 (en) * 2004-11-10 2012-11-20 Matech, Inc. Single transducer full duplex talking circuit
JP5308029B2 (ja) * 2004-11-24 2013-10-09 テクラブ インコーポレイテッド 分析物を検出するための装置および方法
JP4346041B2 (ja) 2005-10-31 2009-10-14 国立大学法人 北海道大学 非液相型化学発光酵素免疫測定法および測定キット
DE102009010563A1 (de) 2009-02-16 2010-08-26 Matthias W. Engel Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten
DE102010011838A1 (de) 2010-03-10 2011-09-15 Ulti Med Products International Gmbh Tragbares Gerät und Test zum Nachweis von Analyten in einer flüssigen Probe
DE102010032718A1 (de) 2010-07-23 2012-01-26 Christoph Gienapp Testgerät

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JPS5618917A (en) * 1979-07-25 1981-02-23 Watanabe Yakuhin Kogyo Kk Sheet hydrous gel
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US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
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US4433059A (en) * 1981-09-08 1984-02-21 Ortho Diagnostic Systems Inc. Double antibody conjugate
US4469787A (en) * 1982-05-14 1984-09-04 Mallinckrodt Inc. Immunoassay involving soluble complex of second antibody and labeled binding protein
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US4510239A (en) * 1982-08-09 1985-04-09 Beckman Instruments, Inc. Double antibody immunoassays of enzymes such as prostatic acid phosphatase
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Also Published As

Publication number Publication date
DE3852040D1 (de) 1994-12-08
US4891313A (en) 1990-01-02
JPH03503928A (ja) 1991-08-29
WO1989006799A1 (en) 1989-07-27
ATE113722T1 (de) 1994-11-15
EP0397775A1 (de) 1990-11-22
DE3852040T2 (de) 1995-04-27
DE3856351T2 (de) 2002-05-16
EP0397775A4 (en) 1991-03-27
CA1336064C (en) 1995-06-27
EP0596867A1 (de) 1994-05-11
EP0596867B1 (de) 1999-07-21
ES2138628T3 (es) 2000-01-16
JP2694469B2 (ja) 1997-12-24
EP0397775B1 (de) 1994-11-02

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: ROCHE DIAGNOSTICS CORP., INDIANAPOLIS, IND., US

8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8327 Change in the person/name/address of the patent owner

Owner name: ROCHE DIAGNOSTICS OPERATIONS, INC., INDIANAPOLIS,

8328 Change in the person/name/address of the agent

Representative=s name: DURM & PARTNER, 76137 KARLSRUHE