DE3852140T2 - Produktion von Proteinen in aktiven Formen. - Google Patents

Produktion von Proteinen in aktiven Formen.

Info

Publication number
DE3852140T2
DE3852140T2 DE3852140T DE3852140T DE3852140T2 DE 3852140 T2 DE3852140 T2 DE 3852140T2 DE 3852140 T DE3852140 T DE 3852140T DE 3852140 T DE3852140 T DE 3852140T DE 3852140 T2 DE3852140 T2 DE 3852140T2
Authority
DE
Germany
Prior art keywords
protein
proteins
production
rupturing
active forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3852140T
Other languages
English (en)
Other versions
DE3852140D1 (de
Inventor
Joseph John Patroni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nantinco Nv Willensted Curacao An
Original Assignee
Southern Cross Biotech Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Cross Biotech Pty Ltd filed Critical Southern Cross Biotech Pty Ltd
Application granted granted Critical
Publication of DE3852140D1 publication Critical patent/DE3852140D1/de
Publication of DE3852140T2 publication Critical patent/DE3852140T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormones [GH] (Somatotropin)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
DE3852140T 1987-02-20 1988-02-16 Produktion von Proteinen in aktiven Formen. Expired - Fee Related DE3852140T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPI046287 1987-02-20

Publications (2)

Publication Number Publication Date
DE3852140D1 DE3852140D1 (de) 1995-01-05
DE3852140T2 true DE3852140T2 (de) 1995-04-06

Family

ID=3772028

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3852140T Expired - Fee Related DE3852140T2 (de) 1987-02-20 1988-02-16 Produktion von Proteinen in aktiven Formen.

Country Status (10)

Country Link
US (1) US4966963A (de)
EP (1) EP0279619B1 (de)
JP (1) JPS63264598A (de)
AT (1) ATE114319T1 (de)
AU (1) AU612133B2 (de)
CA (1) CA1326106C (de)
DE (1) DE3852140T2 (de)
ES (1) ES2065906T3 (de)
NZ (1) NZ223559A (de)
ZA (1) ZA881067B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU612133B2 (en) * 1987-02-20 1991-07-04 Natinco Nv Production of proteins in active forms
AU609824B2 (en) * 1987-06-15 1991-05-09 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
JPH03500601A (ja) * 1987-06-26 1991-02-14 コモンウェルス　サイエンティフィック　アンド　インダストリアル　リサーチ　オーガナイゼイション ウィルス中和及び保護モノクローナル抗体により認識されるｉｂｄｖ　ｖｐ２エピトープ
US5136027A (en) * 1989-05-02 1992-08-04 Abbott Laboratories Method for renaturing proteins in the presence of alkyl sulfate detergents
US5101018A (en) * 1989-06-12 1992-03-31 International Minerals & Chemical Corp. Method for recovering recombinant proteins
DK0432419T3 (da) * 1989-12-05 1994-11-14 American Cyanamid Co Fremgangsmåde til solubilisering og naturering af somatotropiner under anvendelse af lav urinstofkoncentration
AU664021B2 (en) * 1990-09-05 1995-11-02 Natinco Nv Solubilization of proteins in active forms
US6566098B1 (en) * 1990-09-14 2003-05-20 The United States Of America As Represented By The Department Of Health And Human Services DNA encoding truncated hepatocyte growth factor variants
GB2281558B (en) * 1993-09-07 1997-02-19 Joseph Matthew Gaugas Supplying sulphur to plants
US5861372A (en) * 1996-02-22 1999-01-19 The Children's Medical Center Corporation Aggregate angiostatin and method of use
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US5840838A (en) * 1996-02-29 1998-11-24 University Of Kentucky Research Foundation Process for enhancing the activity of amyloid β peptides
US20030190307A1 (en) * 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
EP2158923B1 (de) 1998-08-06 2013-02-27 Mountain View Pharmaceuticals, Inc. Peg-uricase Konjugate und Verwendung davon
PL3321359T3 (pl) 2005-04-11 2021-06-28 Horizon Pharma Rheumatology Llc Wariantowe postacie oksydazy moczanowej i ich zastosowanie
RU2435847C2 (ru) 2005-04-11 2011-12-10 Савиент Фармасьютикалз, Инк. Вариантная форма урат-оксидазы и ее использование
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
WO2006125452A1 (en) * 2005-05-23 2006-11-30 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
ES2532804T3 (es) * 2006-04-12 2015-03-31 Crealta Pharmaceuticals Llc Purificación de proteínas con tensioactivo catiónico
EP2358909B1 (de) 2008-11-17 2015-09-02 Cornell University System zur protokollierung von wechselwirkungen zwischen proteinen im bakteriellen periplasma
KR101861547B1 (ko) 2009-06-25 2018-07-02 크레알타 파마슈티칼스 엘엘씨 페길화된 유리카아제 치료 중에 혈청 요산을 모니터링하여 주입 반응의 위험성 및 반응의 항체­매개 상실을 예측하는 방법 및 키트

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2829089A1 (de) * 1977-07-13 1979-02-01 Sandoz Ag Subunit-vakzine
US4462940A (en) * 1982-09-23 1984-07-31 Cetus Corporation Process for the recovery of human β-interferon-like polypeptides
GR79124B (de) * 1982-12-22 1984-10-02 Genentech Inc
ES8800957A1 (es) * 1985-02-22 1987-12-01 Monsanto Co Un metodo para la solubilizacion y renaturalizacion de proteina somatotropina
US4731440A (en) * 1985-02-22 1988-03-15 Monsanto Company Method of somatotropin solubilization using dimethylsulfone and naturation
US4766224A (en) * 1985-08-19 1988-08-23 International Minerals & Chemical Corp. Purification and activation of proteins from insoluble inclusion bodies
AU597924B2 (en) * 1985-12-11 1990-06-14 Natinco Nv Solubilization of protein aggregates
AU612133B2 (en) * 1987-02-20 1991-07-04 Natinco Nv Production of proteins in active forms
AU607988B2 (en) * 1987-04-21 1991-03-21 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
AU1763188A (en) * 1987-06-15 1988-12-15 Bunge (Australia) Pty Ltd Recovery of proteins in active form

Also Published As

Publication number Publication date
NZ223559A (en) 1989-09-27
CA1326106C (en) 1994-01-11
AU612133B2 (en) 1991-07-04
EP0279619A2 (de) 1988-08-24
ATE114319T1 (de) 1994-12-15
EP0279619A3 (en) 1990-04-11
JPS63264598A (ja) 1988-11-01
DE3852140D1 (de) 1995-01-05
AU1141288A (en) 1988-08-25
US4966963A (en) 1990-10-30
EP0279619B1 (de) 1994-11-23
ES2065906T3 (es) 1995-03-01
ZA881067B (en) 1988-08-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NANTINCO, NV, WILLENSTED, CURACAO, AN

8339 Ceased/non-payment of the annual fee