DE3785615T2 - Hemmungsstoffe der serin-protease. - Google Patents
Hemmungsstoffe der serin-protease.Info
- Publication number
- DE3785615T2 DE3785615T2 DE8787870078T DE3785615T DE3785615T2 DE 3785615 T2 DE3785615 T2 DE 3785615T2 DE 8787870078 T DE8787870078 T DE 8787870078T DE 3785615 T DE3785615 T DE 3785615T DE 3785615 T2 DE3785615 T2 DE 3785615T2
- Authority
- DE
- Germany
- Prior art keywords
- protease inhibitors
- serin protease
- serin
- inhibitors
- protease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87301486A | 1986-06-11 | 1986-06-11 | |
US07/045,833 US4829052A (en) | 1986-06-11 | 1987-05-08 | Serine protease inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3785615D1 DE3785615D1 (de) | 1993-06-03 |
DE3785615T2 true DE3785615T2 (de) | 1993-08-05 |
Family
ID=26723250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8787870078T Expired - Fee Related DE3785615T2 (de) | 1986-06-11 | 1987-06-10 | Hemmungsstoffe der serin-protease. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4829052A (de) |
EP (1) | EP0252057B1 (de) |
JP (1) | JP2520131B2 (de) |
CA (1) | CA1308864C (de) |
DE (1) | DE3785615T2 (de) |
ES (1) | ES2053588T3 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5008242A (en) * | 1986-12-24 | 1991-04-16 | John Lezdey | Treatment of inflammation using 1-antichymotrypsin |
US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
FR2647677B1 (fr) * | 1989-05-31 | 1991-09-27 | Roussel Uclaf | Nouvelles micro-proteines, procede de preparation et application a titre de medicaments de ces nouvelles micro-proteines |
US7413537B2 (en) * | 1989-09-01 | 2008-08-19 | Dyax Corp. | Directed evolution of disulfide-bonded micro-proteins |
DE3938971A1 (de) * | 1989-11-24 | 1991-05-29 | Biotechnolog Forschung Gmbh | Leukozytenelastase und kathepsin g blockierendes peptid, dna, vektor, wirtsorganismus und verfahren zu seiner gewinnung sowie pharmazeutisches praeparat |
WO1992006191A1 (en) * | 1990-09-28 | 1992-04-16 | Protein Engineering Corporation | Proteinaceous anti-dental plaque agents |
US20040087498A1 (en) * | 1991-02-28 | 2004-05-06 | Novo Nordisk Health Care Ag | Modified factor VII |
US5833982A (en) | 1991-02-28 | 1998-11-10 | Zymogenetics, Inc. | Modified factor VII |
US5997864A (en) * | 1995-06-07 | 1999-12-07 | Novo Nordisk A/S | Modified factor VII |
US5788965A (en) * | 1991-02-28 | 1998-08-04 | Novo Nordisk A/S | Modified factor VII |
US5817788A (en) * | 1991-02-28 | 1998-10-06 | Zymogenetics, Inc. | Modified factor VII |
US5861374A (en) * | 1991-02-28 | 1999-01-19 | Novo Nordisk A/S | Modified Factor VII |
JP4146512B2 (ja) * | 1991-03-01 | 2008-09-10 | ダイアックス コープ. | 小型タンパク質 |
US6039944A (en) * | 1992-02-28 | 2000-03-21 | Zymogenetics, Inc. | Modified Factor VII |
US6869925B1 (en) | 1992-09-09 | 2005-03-22 | Amgen Inc. | Inhibition of retrovirus infection |
US5376633A (en) * | 1992-09-30 | 1994-12-27 | Lezdey; John | Method for deactivating viruses in blood component containers |
US5804560A (en) * | 1995-01-06 | 1998-09-08 | Sibia Neurosciences, Inc. | Peptide and peptide analog protease inhibitors |
US6017887A (en) * | 1995-01-06 | 2000-01-25 | Sibia Neurosciences, Inc. | Peptide, peptide analog and amino acid analog protease inhibitors |
GB2318732A (en) * | 1996-11-01 | 1998-05-06 | Johnson & Johnson Medical | Wound healing compositions containing alpha-1-antitrypsin |
US6849605B1 (en) * | 1999-03-05 | 2005-02-01 | The Trustees Of University Technology Corporation | Inhibitors of serine protease activity, methods and compositions for treatment of viral infections |
US6489308B1 (en) | 1999-03-05 | 2002-12-03 | Trustees Of University Of Technology Corporation | Inhibitors of serine protease activity, methods and compositions for treatment of nitric-oxide-induced clinical conditions |
AU3864000A (en) * | 1999-03-05 | 2000-09-21 | Trustees Of University Technology Corporation, The | Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses |
PT1402073E (pt) * | 2001-06-05 | 2007-05-31 | Auckland Uniservices Ltd | Métodos e composições para avaliação da função e distúrbios pulmonares. |
US20040018984A1 (en) * | 2002-07-17 | 2004-01-29 | Mizuo Miyazaki | Methods for preventing adhesion formation using protease inhibitors |
US20040220242A1 (en) * | 2003-05-02 | 2004-11-04 | Leland Shapiro | Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions |
US7850970B2 (en) | 2003-08-26 | 2010-12-14 | The Regents Of The University Of Colorado | Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections |
FR2870382A1 (fr) * | 2004-05-13 | 2005-11-18 | Commissariat Energie Atomique | Cablage de connexion elastique |
CA2608142A1 (en) * | 2005-05-10 | 2006-11-16 | Synergenz Bioscience Limited | Methods and compositions for assessment of pulmonary function and disorders |
AU2006248201A1 (en) * | 2005-05-19 | 2006-11-23 | Synergenz Bioscience Limited | Methods for the assesssment of risk of developing lung cancer using analysis of genetic polymorphisms |
US7933722B2 (en) * | 2005-05-20 | 2011-04-26 | Synergenz Bioscience Limited | Methods of analysis of polymorphisms and uses thereof |
WO2012178102A2 (en) | 2011-06-24 | 2012-12-27 | The Regents Of The Unversity Of Colorado, A Body Corporate | Compositions, methods and uses for alpha-1 antitrypsin fusion molecules |
BR112014003787A2 (pt) * | 2011-08-23 | 2020-10-27 | Synapse B.V. | inibidores termoestáveis de ativação do sistema de coagulação sanguínea por contato com superfícies estranhas |
JP2015504675A (ja) | 2012-01-10 | 2015-02-16 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイトTHE REGENTS OF THE UNIVERSITY OF COLORADO,a body corporate | アルファ−1アンチトリプシン融合分子の組成物、方法、及び使用 |
-
1987
- 1987-05-08 US US07/045,833 patent/US4829052A/en not_active Expired - Lifetime
- 1987-06-10 EP EP87870078A patent/EP0252057B1/de not_active Expired - Lifetime
- 1987-06-10 DE DE8787870078T patent/DE3785615T2/de not_active Expired - Fee Related
- 1987-06-10 JP JP62144997A patent/JP2520131B2/ja not_active Expired - Lifetime
- 1987-06-10 CA CA000539375A patent/CA1308864C/en not_active Expired - Lifetime
- 1987-06-10 ES ES87870078T patent/ES2053588T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0252057B1 (de) | 1993-04-28 |
DE3785615D1 (de) | 1993-06-03 |
EP0252057A2 (de) | 1988-01-07 |
JPS6322027A (ja) | 1988-01-29 |
CA1308864C (en) | 1992-10-13 |
US4829052A (en) | 1989-05-09 |
EP0252057A3 (en) | 1989-08-23 |
ES2053588T3 (es) | 1994-08-01 |
JP2520131B2 (ja) | 1996-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |