DE3785598D1 - Absonderung von langerhansinseln. - Google Patents

Absonderung von langerhansinseln.

Info

Publication number
DE3785598D1
DE3785598D1 DE8787301596T DE3785598T DE3785598D1 DE 3785598 D1 DE3785598 D1 DE 3785598D1 DE 8787301596 T DE8787301596 T DE 8787301596T DE 3785598 T DE3785598 T DE 3785598T DE 3785598 D1 DE3785598 D1 DE 3785598D1
Authority
DE
Germany
Prior art keywords
islets
segment
pancreatic
suspension
langerhans islands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787301596T
Other languages
English (en)
Other versions
DE3785598T2 (de
Inventor
John W Parisius
Anthony Mein-Fang Sun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Ltd
Original Assignee
Connaught Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Connaught Laboratories Ltd filed Critical Connaught Laboratories Ltd
Application granted granted Critical
Publication of DE3785598D1 publication Critical patent/DE3785598D1/de
Publication of DE3785598T2 publication Critical patent/DE3785598T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/09—Means for pre-treatment of biological substances by enzymatic treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Pens And Brushes (AREA)
  • Materials For Medical Uses (AREA)
DE8787301596T 1986-02-24 1987-02-24 Absonderung von langerhansinseln. Expired - Fee Related DE3785598T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868604497A GB8604497D0 (en) 1986-02-24 1986-02-24 Separation of islets of langerhans

Publications (2)

Publication Number Publication Date
DE3785598D1 true DE3785598D1 (de) 1993-06-03
DE3785598T2 DE3785598T2 (de) 1993-09-09

Family

ID=10593561

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787301596T Expired - Fee Related DE3785598T2 (de) 1986-02-24 1987-02-24 Absonderung von langerhansinseln.

Country Status (9)

Country Link
US (1) US4797213A (de)
EP (1) EP0236049B1 (de)
JP (1) JPH0763362B2 (de)
AT (1) ATE88749T1 (de)
CA (1) CA1275923C (de)
DE (1) DE3785598T2 (de)
ES (1) ES2039431T3 (de)
GB (1) GB8604497D0 (de)
GR (1) GR3007751T3 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079160A (en) * 1987-06-08 1992-01-07 Lacy Paul E Method to isolate clusters of cell subtypes from organs
DE4143639C2 (de) * 1991-12-02 2002-10-24 Qiagen Gmbh Verfahren zur Isolierung und Reinigung von Nukleinsäuren
US5830492A (en) * 1992-02-24 1998-11-03 Encelle, Inc. Bioartificial devices and cellular matrices therefor
US5834005A (en) * 1992-02-24 1998-11-10 Encelle, Inc. Bioartificial devices and cellular matrices therefor
US6231881B1 (en) 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
US5824331A (en) * 1992-02-24 1998-10-20 Encelle, Inc. Bioartificial devices and cellular matrices therefor
FR2696754B1 (fr) * 1992-10-14 1994-11-18 Hospal Ind Méthode d'isolement de cellules à partir d'un organe et dispositif pour sa mise en Óoeuvre.
DE4321104B4 (de) * 1993-06-25 2007-04-19 Schrezenmeir, Jürgen, Dr.med. Verfahren und Vorrichtung zum Isolieren von Langerhans-Inseln
US5693513A (en) * 1995-01-10 1997-12-02 Pope; Edward J. A. Encapsulation of living tissue cells in an organosilicon
US5739020A (en) * 1995-01-10 1998-04-14 Pope; Edward J. A. Encapsulation of animal and microbial cells in an inorganic gel prepared from an organosilicon
US5895757A (en) * 1993-06-30 1999-04-20 Pope; Edward J. A. Encapsulation of living tissue cells in inorganic microspheres prepared from an organosilicon
US5409833A (en) * 1993-07-01 1995-04-25 Baxter International Inc. Microvessel cell isolation apparatus
CA2189646C (en) * 1994-06-24 1999-05-25 Francis E. Dwulet A purified mixture of collagenases and two other proteases obtained from clostridium histolyticum
FR2729398A1 (fr) * 1995-01-17 1996-07-19 Hospal R & D Int Dispositif de digestion d'organe et procede pour isoler des cellules ou amas de cellules d'interet biologique a partir d'un organe
US5679565A (en) * 1995-04-10 1997-10-21 The Regents Of The University Of California Method of preserving pancreatic islets
US5670358A (en) * 1995-10-19 1997-09-23 Baxter International Inc. Method for inhibiting chymopapain and papain enzyme activity with polysaccharides of animal origin
US5989888A (en) * 1996-01-24 1999-11-23 Roche Diagnostics Corporation Purified mixture of collagenase I, collagenase II and two other proteases
US5830741A (en) * 1996-12-06 1998-11-03 Boehringer Mannheim Corporation Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease
US5922339A (en) * 1998-01-27 1999-07-13 Usala; Anton-Lewis Compositions and methods for biocompatible implants
WO2001091774A2 (en) 2000-05-31 2001-12-06 Encelle, Inc. Method of treating chronic ulcers
WO2003050249A2 (en) * 2001-12-07 2003-06-19 Geron Corporation Islet cells from human embryonic stem cells
IL162132A0 (en) * 2001-12-07 2005-11-20 Geron Corp Chondrocyte precursors derived from human embryonic stem cells
US20030215935A1 (en) * 2002-05-14 2003-11-20 Coon David James Apparatus and method for isolating living cells from an encapsulated organ tissue sample
JP2005312376A (ja) * 2004-04-30 2005-11-10 Asahi Kasei Corp 細胞表面消化度検出用化合物
DE102006026179A1 (de) * 2006-05-29 2007-12-06 Eberhard-Karls-Universität Tübingen Universitätsklinikum Verfahren zur in vitro Präparation von lebenden Zellen und/oder Zellansammlungen aus einem Gewebe
US8415153B2 (en) 2006-06-19 2013-04-09 Geron Corporation Differentiation and enrichment of islet-like cells from human pluripotent stem cells
US20100159564A1 (en) * 2007-11-30 2010-06-24 Dwulet Francis E Protease resistant recombinant bacterial collagenases
US20100112696A1 (en) * 2008-11-03 2010-05-06 Baxter International Inc. Apparatus And Methods For Processing Tissue To Release Cells
JP5894726B2 (ja) * 2010-07-13 2016-03-30 株式会社大塚製薬工場 膵島の分離方法および膵島組織を保護するための保護液
DE102016114043B3 (de) * 2016-07-29 2017-08-10 Technische Universität Dresden Vorrichtung zur Isolierung von Stammzellen aus fötalen Geweben
CN114672452A (zh) * 2022-05-07 2022-06-28 复旦大学附属中山医院 胰岛细胞及其分离方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3934340A (en) * 1974-08-23 1976-01-27 Disston, Inc. Cutting blade edge construction for mechanically actuated shears
DK140584B (da) * 1975-07-18 1979-10-08 Leo Sa Lab Fremgangsmåde til findeling af frosne blokke af animalske organer eller animalsk væv.
US4477567A (en) * 1977-12-01 1984-10-16 Connaught Laboratories Limited Continuous bovine beta cell line
US4205570A (en) * 1978-12-22 1980-06-03 Arnold Soodalter Meat cubing apparatus
US4332893A (en) * 1980-06-13 1982-06-01 Rosenberg Ralph A Process for the production of an insulin-producing cell line of pancreatic beta cells
JPS61183226A (ja) * 1985-02-07 1986-08-15 マクドネル　ダグラス　コーポレイシヨン ランゲルハンス島の単離法
US4868121A (en) * 1985-02-07 1989-09-19 Mcdonnell Douglas Corporation Islet isolation process

Also Published As

Publication number Publication date
JPH0763362B2 (ja) 1995-07-12
GB8604497D0 (en) 1986-04-03
CA1275923C (en) 1990-11-06
DE3785598T2 (de) 1993-09-09
ATE88749T1 (de) 1993-05-15
JPS62265981A (ja) 1987-11-18
GR3007751T3 (de) 1993-08-31
ES2039431T3 (es) 1993-10-01
EP0236049A2 (de) 1987-09-09
EP0236049B1 (de) 1993-04-28
EP0236049A3 (en) 1989-03-15
US4797213A (en) 1989-01-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee