DE3782917D1 - Verfahren zum herabsetzen des gehalts an rueckstaendigen aldehyden in implantierbaren bioprosthetischen geweben. - Google Patents

Verfahren zum herabsetzen des gehalts an rueckstaendigen aldehyden in implantierbaren bioprosthetischen geweben.

Info

Publication number
DE3782917D1
DE3782917D1 DE8787114789T DE3782917T DE3782917D1 DE 3782917 D1 DE3782917 D1 DE 3782917D1 DE 8787114789 T DE8787114789 T DE 8787114789T DE 3782917 T DE3782917 T DE 3782917T DE 3782917 D1 DE3782917 D1 DE 3782917D1
Authority
DE
Germany
Prior art keywords
reducing
content
residual aldehydes
bioprosthetic tissues
implantable bioprosthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787114789T
Other languages
English (en)
Inventor
Ronald Dieck
Aws Nashef
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Application granted granted Critical
Publication of DE3782917D1 publication Critical patent/DE3782917D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/0231—Chemically defined matrices, e.g. alginate gels, for immobilising, holding or storing cells, tissue or organs for preservation purposes; Chemically altering or fixing cells, tissue or organs, e.g. by cross-linking, for preservation purposes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/915—Method or apparatus for preparing biological material
    • Y10S623/916—Blood vessel

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)
DE8787114789T 1986-10-10 1987-10-09 Verfahren zum herabsetzen des gehalts an rueckstaendigen aldehyden in implantierbaren bioprosthetischen geweben. Expired - Lifetime DE3782917D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/917,503 US4786287A (en) 1986-10-10 1986-10-10 Process for decreasing residual aldehyde levels in implantable bioprosthetic tissue

Publications (1)

Publication Number Publication Date
DE3782917D1 true DE3782917D1 (de) 1993-01-14

Family

ID=25438884

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787114789T Expired - Lifetime DE3782917D1 (de) 1986-10-10 1987-10-09 Verfahren zum herabsetzen des gehalts an rueckstaendigen aldehyden in implantierbaren bioprosthetischen geweben.

Country Status (4)

Country Link
US (1) US4786287A (de)
EP (1) EP0267434B1 (de)
JP (1) JPS63177862A (de)
DE (1) DE3782917D1 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5746775A (en) * 1988-04-01 1998-05-05 The Board Of Regent6S Of The University Of Michigan Method of making calcification-resistant bioprosthetic tissue
US5368608A (en) * 1988-04-01 1994-11-29 University Of Michigan, The Board Of Regents Calcification-resistant materials and methods of making same through use of multivalent cations
AT398276B (de) * 1989-05-31 1994-11-25 Sorin Biomedica Spa Verfahren zur präparierung von biologischem implantationsmaterial
US5476516A (en) * 1992-03-13 1995-12-19 Albert Einstein College Of Medicine Of Yeshiva University Anticalcification treatment for aldehyde-tanned biological tissue
US5447536A (en) * 1994-02-17 1995-09-05 Biomedical Design, Inc. Method for fixation of biological tissue
US5595571A (en) * 1994-04-18 1997-01-21 Hancock Jaffe Laboratories Biological material pre-fixation treatment
US5931969A (en) 1994-07-29 1999-08-03 Baxter International Inc. Methods and apparatuses for treating biological tissue to mitigate calcification
CA2196165C (en) 1994-07-29 2004-06-08 Sophie Carpentier Methods for treating implantable biological tissues to mitigate the calcification thereof and bioprosthetic articles treated by such methods
USRE40570E1 (en) 1994-07-29 2008-11-11 Edwards Lifesciences Corporation Apparatuses and methods for treating biological tissue to mitigate calcification
US5919472A (en) * 1996-03-19 1999-07-06 Medtronic, Inc. Treatment of aldehyde-fixed tissue
US6506339B1 (en) 1997-02-10 2003-01-14 Biomedical Design, Inc. Method of sterilization
JP4271262B2 (ja) * 1997-02-10 2009-06-03 バイオメディカル デザイン インコーポレイテッド 滅菌法
US7722671B1 (en) 1998-01-27 2010-05-25 St. Jude Medical, Inc. Medical devices with associated growth factors
US6214054B1 (en) * 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
CA2345799C (en) 1998-09-30 2010-01-05 Medtronic, Inc. Process for reducing mineralization of tissue used in transplantation
US6214055B1 (en) * 1998-10-30 2001-04-10 Mures Cardiovascular Research, Inc. Method and kit for rapid preparation of autologous tissue medical devices
US6375680B1 (en) 1998-12-01 2002-04-23 St. Jude Medical, Inc. Substrates for forming synthetic tissues
US6670520B2 (en) * 1999-05-28 2003-12-30 Ethicon, Inc. Reductive amination for aldehyde neutralization
US20040084060A1 (en) * 1999-05-28 2004-05-06 Peter Zhu Method and kit for removing aldehyde-based stains
US6471723B1 (en) * 2000-01-10 2002-10-29 St. Jude Medical, Inc. Biocompatible prosthetic tissue
US6541560B1 (en) 2000-03-15 2003-04-01 Graphic Packaging Corporation Control of volatile carbonyl compound in compositions used in printing, printing methods and resulting printed structure
US7078163B2 (en) * 2001-03-30 2006-07-18 Medtronic, Inc. Process for reducing mineralization of tissue used in transplantation
DE10134568C2 (de) * 2001-07-16 2003-07-24 Inst Chemo Biosensorik Verfahren zur quantitativen Bestimmung von alpha-Oxoaldehyd
US20030093147A1 (en) * 2001-11-13 2003-05-15 Ogle Matthew F. Medical devices that stimulate growth factor production
US6878168B2 (en) 2002-01-03 2005-04-12 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
US7955788B2 (en) * 2003-10-30 2011-06-07 Medtronic, Inc. Bioprosthetic tissue preparation with synthetic hydrogels
US20050266390A1 (en) * 2004-06-01 2005-12-01 Yuichiro Ueda Processes for removing cells and cell debris from tissue and tissue constructs used in transplantation and tissue reconstruction
US20060110370A1 (en) * 2004-11-23 2006-05-25 Pathak Chandrashenkhar P Treatments for reduction of cytotoxicity and viral contamination of implantable medical devices
JP4626350B2 (ja) * 2005-03-22 2011-02-09 ソニー株式会社 ハイブリダイゼーション検出に適する反応部などを有する流路系、該流路系を用いるハイブリダイゼーション検出装置
US7579381B2 (en) * 2005-03-25 2009-08-25 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
JP2009508938A (ja) * 2005-09-22 2009-03-05 ハダシット メディカル リサーチ サーヴィスィズ アンド ディベロップメント リミテッド 治療上活性な化合物の結合体
CN103933612B (zh) 2006-10-27 2016-06-22 爱德华兹生命科学公司 用于外科植入的生物组织
US9101691B2 (en) * 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
CA2794121C (en) 2010-03-23 2016-10-11 Edwards Lifesciences Corporation Methods of conditioning sheet bioprosthetic tissue
US8906601B2 (en) 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
WO2011160085A2 (en) 2010-06-17 2011-12-22 Edwards Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
US9358107B2 (en) 2011-06-30 2016-06-07 Edwards Lifesciences Corporation Systems, dies, and methods for processing pericardial tissue
US10238771B2 (en) * 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
WO2016044313A1 (en) * 2014-09-16 2016-03-24 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for the removal of aldehyde adducts and crosslinks from biomolecules
WO2016154452A2 (en) 2015-03-24 2016-09-29 Osiris Therapeutics, Inc. Compositions comprising meniscal tissues and uses thereof
WO2018222434A1 (en) 2017-05-31 2018-12-06 Edwards Lifesciences Corporation Collagen fibers and articles formed therefrom
SG11202003938PA (en) 2018-01-23 2020-08-28 Edwards Lifesciences Corp Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby
EP3852683B1 (de) 2018-11-01 2024-05-29 Edwards Lifesciences Corporation Pulmonales regeneratives transkatheterventil
CN110917399A (zh) * 2019-12-09 2020-03-27 沛嘉医疗科技(苏州)有限公司 生物材料的抗钙化方法及生物材料

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1785092A (en) * 1927-03-15 1930-12-16 Tanners Council Of The United Process of unhairing hides or skins
US3988782A (en) * 1973-07-06 1976-11-02 Dardik Irving I Non-antigenic, non-thrombogenic infection-resistant grafts from umbilical cord vessels and process for preparing and using same
US3966401A (en) * 1974-07-01 1976-06-29 Hancock Laboratories Incorporated Preparing natural tissue for implantation so as to provide improved flexibility
GB1493459A (en) * 1975-01-23 1977-11-30 Dardik I Non-antigenic non-thrombogenic infection resistant grafts from umbilical cord vessels and process for preparing sam
IL47062A (en) * 1975-04-10 1979-07-25 Yeda Res & Dev Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde
WO1982000091A1 (en) * 1980-07-01 1982-01-21 V Ketharanathan Vascular prostheses
US4323358A (en) * 1981-04-30 1982-04-06 Vascor, Inc. Method for inhibiting mineralization of natural tissue during implantation
FR2523810B1 (fr) * 1982-03-23 1988-11-25 Carpentier Alain Tissu biologique greffable et procede pour sa preparation
US4481009A (en) * 1982-05-13 1984-11-06 American Hospital Supply Corporation Polymer incorporation into implantable biological tissue to inhibit calcification
US4402697A (en) * 1982-08-25 1983-09-06 Extracorporeal Medical Specialties, Inc. Method for inhibiting mineralization of natural tissue during implantation
US4405327A (en) * 1982-08-25 1983-09-20 Extracorporeal Medical Specialties, Inc. Method for inhibiting mineralization of natural tissue during implantation
US4553974A (en) * 1984-08-14 1985-11-19 Mayo Foundation Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor

Also Published As

Publication number Publication date
US4786287A (en) 1988-11-22
EP0267434B1 (de) 1992-12-02
EP0267434A2 (de) 1988-05-18
EP0267434A3 (en) 1988-08-03
JPS63177862A (ja) 1988-07-22

Similar Documents

Publication Publication Date Title
DE3782917D1 (de) Verfahren zum herabsetzen des gehalts an rueckstaendigen aldehyden in implantierbaren bioprosthetischen geweben.
DE3770239D1 (de) Mundstueck und verfahren zum herstellen von diesem.
DE3674308D1 (de) Biozide zusammensetzungund verfahren zur behandlung von wasser.
DE3869490D1 (de) Verfahren zur elektrochemischen behandlung von stoffen.
DE68918943D1 (de) Gewebeentzusammensetzung und verfahren.
DK173478A (da) Anlaeg til regulering af offentlige transportmidlers trafis i byomraader
DE3873847D1 (de) Behandlungsapparat und -verfahren.
DE69010893D1 (de) Verfahren zur behandlung von koks sowie löschen desselben.
DE3784836D1 (de) Verfahren zum herstellen von schichtstoffteilen.
DE3767123D1 (de) Verfahren zur bestimmung des haematokrit aus vollblut sowie vorrichtung zur durchfuehrung des verfahrens.
DE68905117D1 (de) Verfahren zur stabilisierung von blutgewinnungsfaktoren.
DE68900949D1 (de) Verfahren zur trennung von wasserstoffbehandlungs-ausfluessen.
DE3876019D1 (de) Verfahren und vorrichtung zum herstellen von pyramidenstumpffoermiger dosenzargen.
DE58904461D1 (de) Verfahren zum herstellen von schaumstoffpolstern.
DE68904492D1 (de) Verfahren zur extraktion von kaffee.
DE3764284D1 (de) Behandlungsverfahren zur holzkonservierung und holzkonservierungsmittel zum verfahren.
DE58901845D1 (de) Verfahren zum festlegen.
DE3668505D1 (de) Diabehaelter und verfahren zum automatischen einfuehren der dias in den behaelter.
DE3750397D1 (de) Verfahren zum testen von körperflüssigkeiten.
DE68903208D1 (de) Verfahren zur thermischen behandlung von laktoferrin.
DE3874638D1 (de) Behandlungsapparat und -verfahren.
DE68905163D1 (de) Verfahren zum sterilisieren.
ATE121264T1 (de) Verfahren zum abtöten von mollusken.
DE3882414D1 (de) Klebrigmacher und klebstoffzusammensetzungen, verfahren zum kleben und damit verklebte gegenstaende.
DE3883896D1 (de) Diamantverbundkörper und Verfahren zu seiner Herstellung.

Legal Events

Date Code Title Description
8332 No legal effect for de