DE3778133D1 - Mitomycinderivate. - Google Patents

Mitomycinderivate.

Info

Publication number
DE3778133D1
DE3778133D1 DE8787310937T DE3778133T DE3778133D1 DE 3778133 D1 DE3778133 D1 DE 3778133D1 DE 8787310937 T DE8787310937 T DE 8787310937T DE 3778133 T DE3778133 T DE 3778133T DE 3778133 D1 DE3778133 D1 DE 3778133D1
Authority
DE
Germany
Prior art keywords
mitomycine
derivatives
mitomycine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787310937T
Other languages
English (en)
Inventor
Yasushi Shida
Tokuyuki Kuroda
Ikuo Matsukuma
Makoto Morimoto
Tadashi Ashizawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of DE3778133D1 publication Critical patent/DE3778133D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8787310937T 1986-12-13 1987-12-11 Mitomycinderivate. Expired - Lifetime DE3778133D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61296990A JPS63150282A (ja) 1986-12-13 1986-12-13 マイトマイシン誘導体

Publications (1)

Publication Number Publication Date
DE3778133D1 true DE3778133D1 (de) 1992-05-14

Family

ID=17840822

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787310937T Expired - Lifetime DE3778133D1 (de) 1986-12-13 1987-12-11 Mitomycinderivate.

Country Status (4)

Country Link
US (1) US4863935A (de)
EP (1) EP0272063B1 (de)
JP (1) JPS63150282A (de)
DE (1) DE3778133D1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0485904B1 (de) * 1990-11-13 1997-08-20 Kyowa Hakko Kogyo Co., Ltd. Mitomycinderivate
US5583259A (en) * 1991-02-08 1996-12-10 Les Laboratoires Beecham S.A. 2-(RO)-1-(R) ethylamines
ES2299177T3 (es) 1995-05-10 2008-05-16 Kyowa Hakko Kogyo Co., Ltd. Conjugados de citotoxinas que contienen dipeptidos.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374774A (en) * 1979-03-13 1983-02-22 Kyowa Hakko Kogyo Co., Ltd. Mitomycins
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
EP0116208B1 (de) * 1982-12-07 1988-03-30 Kyowa Hakko Kogyo Co., Ltd. Mitomycin-Analoge
JPS59175493A (ja) * 1983-03-25 1984-10-04 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPS59104386A (ja) * 1982-12-07 1984-06-16 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
NZ206932A (en) * 1983-02-07 1987-08-31 University Patents Inc Certain 6-(heterocyclyl or amino) mitosanes and pharmaceutical compositions
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤
EP0197799B1 (de) * 1985-04-10 1990-09-12 Kyowa Hakko Kogyo Kabushiki Kaisha Pharmakologisch aktive Mitomycinderivate

Also Published As

Publication number Publication date
US4863935A (en) 1989-09-05
EP0272063B1 (de) 1992-04-08
EP0272063A1 (de) 1988-06-22
JPS63150282A (ja) 1988-06-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee