DE3765888D1 - Verfahren zur herstellung von l-dopa. - Google Patents
Verfahren zur herstellung von l-dopa.Info
- Publication number
- DE3765888D1 DE3765888D1 DE8787307131T DE3765888T DE3765888D1 DE 3765888 D1 DE3765888 D1 DE 3765888D1 DE 8787307131 T DE8787307131 T DE 8787307131T DE 3765888 T DE3765888 T DE 3765888T DE 3765888 D1 DE3765888 D1 DE 3765888D1
- Authority
- DE
- Germany
- Prior art keywords
- dopa
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/24—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from hydantoins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/34—Preparation of optical isomers by separation of optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/899,283 US4716246A (en) | 1986-08-22 | 1986-08-22 | Process for L-dopa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3765888D1 true DE3765888D1 (de) | 1990-12-06 |
Family
ID=25410727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8787307131T Expired - Fee Related DE3765888D1 (de) | 1986-08-22 | 1987-08-12 | Verfahren zur herstellung von l-dopa. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4716246A (de) |
| EP (1) | EP0257920B1 (de) |
| JP (1) | JPS6360955A (de) |
| CA (1) | CA1292478C (de) |
| DE (1) | DE3765888D1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4129062A1 (de) * | 1991-09-02 | 1993-03-04 | Merck Patent Gmbh | Verfahren zur enantiomerentrennung von 5-hetaryl-1,3,4-thiadiazinonen |
| US5393908A (en) * | 1992-06-25 | 1995-02-28 | Satyamurthy; Nagichettiar | Synthesis of N-formyl-3,4-di-t-butoxycarbonyloxy-6-(trimethylstannyl)-L-phenylalanine ethyl ester and its regioselective radiofluorodestannylation to 6-[18 F]fluoro-L-dopa |
| CA2553156A1 (en) * | 2003-10-20 | 2005-05-12 | Teva Pharmaceutical Industries Ltd. | Composition and dosage form for sustained effect of levodopa |
| US7022872B2 (en) * | 2003-12-19 | 2006-04-04 | Molecular Technologies, Inc. | Method for making fluorine labeled L-Dopa |
| CN104945270B (zh) * | 2015-05-01 | 2017-08-15 | 李玉山 | 一种左旋多巴甲酯盐酸盐的合成方法 |
| CN114315619B (zh) * | 2022-01-17 | 2023-03-24 | 山东泓瑞医药科技股份公司 | 一种二甲氧基多巴的合成方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2605282A (en) * | 1949-02-18 | 1952-07-29 | Dow Chemical Co | Process for production of beta-(3, 4-dihydroxyphenyl)-alanine |
| US3721697A (en) * | 1962-10-11 | 1973-03-20 | Merck & Co Inc | Resolution of dl-alpha-lower alkanoyl-amino-alpha-(benzyl)propionitriles |
| US3405159A (en) * | 1964-11-17 | 1968-10-08 | Merck & Co Inc | Process for resolving racemic mixtures of optically-active enantiomorphs |
| US3676482A (en) * | 1969-03-14 | 1972-07-11 | Merck & Co Inc | Racemization of an alpha-methyl dopa derivative |
| US3892539A (en) * | 1969-09-26 | 1975-07-01 | Merck & Co Inc | Process for production of crystals in fluidized bed crystallizers |
| AT313258B (de) * | 1969-10-28 | 1974-02-11 | Egyt Gyogyszervegyeszeti Gyar | Verfahren zur Herstellung von optisch aktivem 3,4-Dihydroxyphenylalanin |
| US4005127A (en) * | 1971-03-08 | 1977-01-25 | Monsanto Company | L-Dopa process and intermediates |
| JPS5811421B2 (ja) * | 1975-04-03 | 1983-03-02 | 住友化学工業株式会社 | アルフア− − アミノサンノセイゾウホウ |
| DE3003898A1 (de) * | 1980-02-02 | 1981-08-13 | Dynamit Nobel Ag, 5210 Troisdorf | Verfahren zur acylierung von aminocarbonsaeuren |
| DE3105008A1 (de) * | 1981-02-12 | 1982-08-19 | Degussa Ag, 6000 Frankfurt | Verfahren zur herstellung waessriger loesungen der natriumsalze von (alpha)-aminocarbonsaeuren |
-
1986
- 1986-08-22 US US06/899,283 patent/US4716246A/en not_active Expired - Lifetime
-
1987
- 1987-08-12 DE DE8787307131T patent/DE3765888D1/de not_active Expired - Fee Related
- 1987-08-12 EP EP87307131A patent/EP0257920B1/de not_active Expired
- 1987-08-19 CA CA000544844A patent/CA1292478C/en not_active Expired - Fee Related
- 1987-08-22 JP JP62207428A patent/JPS6360955A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0257920B1 (de) | 1990-10-31 |
| US4716246A (en) | 1987-12-29 |
| EP0257920A1 (de) | 1988-03-02 |
| JPS6360955A (ja) | 1988-03-17 |
| CA1292478C (en) | 1991-11-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3762745D1 (de) | Verfahren zur herstellung von 2-chlor-5-chlormethylthiazol. | |
| DE3765009D1 (de) | Verfahren zur herstellung von 4-acetoxy-3-hydroxyaethyl-azetidin-2-one-derivaten. | |
| DE3763558D1 (de) | Verfahren zur herstellung von 2-chlor-5-chlormethylpyridin. | |
| DE3773889D1 (de) | Verfahren zur herstellung von merkaptomethylphenolen. | |
| DE3853160D1 (de) | Verfahren zur herstellung von elektrophotographien. | |
| DE3865476D1 (de) | Verfahren zur herstellung von aminopropylalkoxysilanen. | |
| DE3780704D1 (de) | Verfahren zur herstellung von n-acyltetrahydroisochinoline. | |
| DE3785530D1 (de) | Verfahren zur herstellung von l-arginin. | |
| DE3860666D1 (de) | Verfahren zur herstellung von hexabromcyclododekan. | |
| DE3863586D1 (de) | Verfahren zur herstellung von m-triflourmethylphenylacetonitril. | |
| DE3861891D1 (de) | Verfahren zur herstellung von epichlorhydrinen. | |
| DE3776440D1 (de) | Verfahren zur herstellung von 5-aminosalicylsaeure. | |
| DE3765129D1 (de) | Verfahren zur herstellung von nitrilen. | |
| DE3766910D1 (de) | Verfahren zur herstellung von dihydrocyclocitral. | |
| DE3769076D1 (de) | Verfahren zur herstellung von fluorbenzaldehyden. | |
| DE3761539D1 (de) | Verfahren zur herstellung von verbundteilen. | |
| DE3765090D1 (de) | Verfahren zur herstellung von 2-acylfuranderivaten. | |
| DE3863321D1 (de) | Verfahren zur herstellung von naphthacenen. | |
| DE3765888D1 (de) | Verfahren zur herstellung von l-dopa. | |
| DE3769263D1 (de) | Verfahren zur herstellung von bromfluoroethylhypofluorit. | |
| DE3777475D1 (de) | Verfahren zur herstellung von polyphenylen-ether-polyester-copolymeren. | |
| DE3772350D1 (de) | Verfahren zur herstellung von dithiolen. | |
| ATA304487A (de) | Verfahren zur herstellung von 9alpha-hydroxy-4-androsten-3,17-dion | |
| DE3767948D1 (de) | Verfahren zur herstellung von tertiaeren alkylphosphanen. | |
| DE3780107D1 (de) | Verfahren zur herstellung von hydroxynaphthalenen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |