DE3751997T2 - Aktives protein in humoraler hyperkalzemia, durch bösartigkeit verursacht - Google Patents

Aktives protein in humoraler hyperkalzemia, durch bösartigkeit verursacht

Info

Publication number
DE3751997T2
DE3751997T2 DE3751997T DE3751997T DE3751997T2 DE 3751997 T2 DE3751997 T2 DE 3751997T2 DE 3751997 T DE3751997 T DE 3751997T DE 3751997 T DE3751997 T DE 3751997T DE 3751997 T2 DE3751997 T2 DE 3751997T2
Authority
DE
Germany
Prior art keywords
hypercalzemia
viciousness
humoral
caused
active protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3751997T
Other languages
English (en)
Other versions
DE3751997D1 (de
Inventor
Thomas Martin
Jane Moseley
Bruce Kemp
Richard Wettenhall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Melbourne
Original Assignee
University of Melbourne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Melbourne filed Critical University of Melbourne
Publication of DE3751997D1 publication Critical patent/DE3751997D1/de
Application granted granted Critical
Publication of DE3751997T2 publication Critical patent/DE3751997T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE3751997T 1986-07-18 1987-06-04 Aktives protein in humoraler hyperkalzemia, durch bösartigkeit verursacht Expired - Lifetime DE3751997T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPH702786 1986-07-18
AUPI034987 1987-02-13
PCT/AU1987/000165 WO1988000596A1 (en) 1986-07-18 1987-06-04 A PROTEIN ACTIVE IN HUMORAL HYPERCALCEMIA OF MALIGNANCY-PTHrP

Publications (2)

Publication Number Publication Date
DE3751997D1 DE3751997D1 (de) 1997-02-20
DE3751997T2 true DE3751997T2 (de) 1997-07-10

Family

ID=25643132

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3751997T Expired - Lifetime DE3751997T2 (de) 1986-07-18 1987-06-04 Aktives protein in humoraler hyperkalzemia, durch bösartigkeit verursacht

Country Status (6)

Country Link
US (4) US5116952A (de)
EP (1) EP0273928B1 (de)
JP (3) JP2598801B2 (de)
CA (1) CA1341030C (de)
DE (1) DE3751997T2 (de)
WO (1) WO1988000596A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2598801B2 (ja) * 1986-07-18 1997-04-09 ザ ユニバーシティー オブ メルボルン 悪性‐ＰＴＨｒＰの液性過カルシウム血症において活性なタンパク
US5312810A (en) * 1987-05-20 1994-05-17 The University Of Melbourne Method and compositions for making ACSF and ACSF antagonists
WO1988009376A1 (en) * 1987-05-20 1988-12-01 Genentech, Inc. Method and compositions for making acsf and acsf antagonists
US5605815A (en) * 1988-03-14 1997-02-25 Yale University Nucleic acids encoding and expression of parathyroid hormone-like peptide
DE68921665T2 (de) * 1988-05-09 1995-09-21 Merck & Co Inc Hemmer vom flüssigen kalziumerhöhenden Faktor.
US5114843A (en) * 1988-05-09 1992-05-19 Merck & Co., Inc. Humoral hypercalcemic factor antagonists
JP2952951B2 (ja) * 1990-04-12 1999-09-27 三菱化学株式会社 ペプチド誘導体
US5149779A (en) * 1990-07-26 1992-09-22 Merck & Co., Inc. Humoral hypercalcemic factor antagonists
US5312747A (en) * 1990-12-17 1994-05-17 Li Yu Teh Isolation, purification and utilization of sialidase-L in the synthesis of 2,7-anhydro-N-acetylneuraminic acid and for the selective cleavage of sialylα2-3 D-galactose linkage
US5382658A (en) * 1992-04-03 1995-01-17 Allelix Biopharmaceuticals Inc. Stability-enhanced variants of parathyroid hormone
US5589452A (en) * 1992-07-14 1996-12-31 Syntex (U.S.A.) Inc. Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
US5977070A (en) * 1992-07-14 1999-11-02 Piazza; Christin Teresa Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
AU5014793A (en) * 1992-08-28 1994-03-29 Magainin Pharmaceuticals, Inc. Purification of amphiphilic compounds
US5266686A (en) * 1992-09-25 1993-11-30 Pierce Chemical Company Method for isolation and purification of enzyme-antibody conjugates
US5993817A (en) * 1995-01-23 1999-11-30 Xenotech Method to ameliorate osteolysis and metastasis
US5626845A (en) * 1995-01-23 1997-05-06 Xenotech Incorporated Method to ameliorate osteolysis and metastasis
ATE219945T1 (de) * 1995-01-23 2002-07-15 Xenotech Inc Zusammensetzung zur verhinderung von osteolyse und metastasen
CA2274987C (en) * 1996-12-23 2012-01-24 Immunex Corporation Ligand for receptor activator of nf-kappa b, ligand is member of tnf superfamily
US6689566B1 (en) 1999-01-14 2004-02-10 Scantibodies Laboratory, Inc. Methods, kits, and antibodies for detecting parathyroid hormone
US7820393B2 (en) * 1999-01-14 2010-10-26 Scantibodies Laboratory, Inc. Methods, kits and antibodies for detecting parathyroid hormone
JP4516711B2 (ja) * 1999-12-28 2010-08-04 中外製薬株式会社 安定な抗体組成物及び注射製剤
US20030082179A1 (en) * 2001-07-03 2003-05-01 Hutchison James Scott Parathyroid hormone antibodies and related methods
US20050069962A1 (en) 2001-10-12 2005-03-31 Archer Robert M Antibody complexes and methods for immunolabeling
US8323903B2 (en) * 2001-10-12 2012-12-04 Life Technologies Corporation Antibody complexes and methods for immunolabeling
CA2472472A1 (en) * 2002-01-10 2003-07-24 Osteotrophin Llc Treatment of bone disorders with skeletal anabolic drugs
EP1513547A4 (de) * 2002-05-23 2009-11-04 Michael F Holick Verwendung von parathormone-peptid-analoga zur behandlung von scheidenatrophie
AU2002951372A0 (en) * 2002-09-13 2002-09-26 St Vincent's Institute Of Medical Research Parathyroid hormone-like polypeptides
US8133505B2 (en) 2002-10-31 2012-03-13 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
IL152574A (en) * 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
US7254303B2 (en) * 2004-03-23 2007-08-07 Corning Cable Systems, Llc. Optical tube assembly having a dry insert and methods of making the same
US8563513B2 (en) * 2009-03-27 2013-10-22 Van Andel Research Institute Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
WO2015025335A1 (en) * 2013-08-21 2015-02-26 Cadila Healthcare Limited Purification process for pth

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886132A (en) * 1972-12-21 1975-05-27 Us Health Human parathyroid hormone
US4105602A (en) * 1975-02-10 1978-08-08 Armour Pharmaceutical Company Synthesis of peptides with parathyroid hormone activity
US4086196A (en) * 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
US4391904A (en) * 1979-12-26 1983-07-05 Syva Company Test strip kits in immunoassays and compositions therein
SE453510B (sv) * 1980-12-29 1988-02-08 Toyo Jozo Kk Peptid for analys av humant paratyroidhormon
US4423037A (en) * 1982-05-13 1983-12-27 The General Hospital Corporation Inhibitors of peptide hormone action
JP2598801B2 (ja) * 1986-07-18 1997-04-09 ザ ユニバーシティー オブ メルボルン 悪性‐ＰＴＨｒＰの液性過カルシウム血症において活性なタンパク
US5312810A (en) * 1987-05-20 1994-05-17 The University Of Melbourne Method and compositions for making ACSF and ACSF antagonists
US4968669A (en) * 1988-05-09 1990-11-06 Merck & Co., Inc. Parathyroid hormone antagonists

Also Published As

Publication number Publication date
US5872221A (en) 1999-02-16
DE3751997D1 (de) 1997-02-20
EP0273928B1 (de) 1997-01-08
WO1988000596A1 (en) 1988-01-28
US5703207A (en) 1997-12-30
JP2807660B2 (ja) 1998-10-08
JP2657053B2 (ja) 1997-09-24
EP0273928A1 (de) 1988-07-13
EP0273928A4 (de) 1990-07-04
JPH08211053A (ja) 1996-08-20
US5116952A (en) 1992-05-26
US5460978A (en) 1995-10-24
JPH01501148A (ja) 1989-04-20
JP2598801B2 (ja) 1997-04-09
JPH09216899A (ja) 1997-08-19
CA1341030C (en) 2000-06-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition