DE369080C - Process for the production of carbonic acid developing mixtures for the treatment of wounds and body cavities - Google Patents
Process for the production of carbonic acid developing mixtures for the treatment of wounds and body cavitiesInfo
- Publication number
- DE369080C DE369080C DEL52997D DEL0052997D DE369080C DE 369080 C DE369080 C DE 369080C DE L52997 D DEL52997 D DE L52997D DE L0052997 D DEL0052997 D DE L0052997D DE 369080 C DE369080 C DE 369080C
- Authority
- DE
- Germany
- Prior art keywords
- carbonic acid
- wounds
- body cavities
- treatment
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title claims description 11
- 238000000034 method Methods 0.000 title claims description 6
- 206010052428 Wound Diseases 0.000 title claims description 4
- 208000027418 Wounds and injury Diseases 0.000 title claims description 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 title claims description 4
- 238000004519 manufacturing process Methods 0.000 title claims description 4
- 239000000126 substance Substances 0.000 claims description 5
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 claims description 4
- 239000000084 colloidal system Substances 0.000 claims description 4
- 239000006260 foam Substances 0.000 claims description 4
- 229920000159 gelatin Polymers 0.000 description 4
- 235000019322 gelatine Nutrition 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 108010010803 Gelatin Proteins 0.000 description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 3
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 3
- 239000008273 gelatin Substances 0.000 description 3
- 235000011852 gelatine desserts Nutrition 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- QCVGEOXPDFCNHA-UHFFFAOYSA-N 5,5-dimethyl-2,4-dioxo-1,3-oxazolidine-3-carboxamide Chemical compound CC1(C)OC(=O)N(C(N)=O)C1=O QCVGEOXPDFCNHA-UHFFFAOYSA-N 0.000 description 2
- 229920001353 Dextrin Polymers 0.000 description 2
- 102000002322 Egg Proteins Human genes 0.000 description 2
- 108010000912 Egg Proteins Proteins 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- DIZPMCHEQGEION-UHFFFAOYSA-H aluminium sulfate (anhydrous) Chemical compound [Al+3].[Al+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O DIZPMCHEQGEION-UHFFFAOYSA-H 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000000645 desinfectant Substances 0.000 description 2
- 235000014103 egg white Nutrition 0.000 description 2
- 210000000969 egg white Anatomy 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 239000000454 talc Substances 0.000 description 2
- 229910052623 talc Inorganic materials 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 239000001828 Gelatine Substances 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 150000003892 tartrate salts Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Description
Verfahren zur Herstellung Kohlensäure entwickelnder Gemische zur Behandlung von Wunden und Körperhöhlen. Im Hauptpatent z594.93 ist ein Verfahren zur Herstellung von Desinfektionsmitteln oder Heilmitteln für die Behandlung von Wunden oder Körperhöhlen geschützt, welches in der Zugabe eines die Schaumbildung begünstigenden Stoffes in der für die Erzeugung eines stehenbleibenden, .zähen Schaumes erforderlichen Menge besteht. Die hierfür zuzusetzenden Stoffe- sind organische Kolloide, wie Gelatine, Eiweiß, @Dextrin: o: dgl.Process for the preparation of carbonic acid evolving mixtures for treatment of wounds and body cavities. In the main patent z594.93 there is a method of manufacture of disinfectants or remedies for treating wounds or body cavities protected, which in the addition of a foam-promoting substance in that required for the production of a persistent, tough foam Crowd exists. The substances to be added for this are organic colloids, such as gelatin, Protein, @dextrin: o: like.
Das vorliegende Verfahren besteht darin, daß man zur Herstellung der brausenden oder gasentwickelnden Mischung Stoffe verwendet, die mit dem zweiten Bestandteil nicht nur die Entstehung eines. Schaumes oder die Entwicklung von Gas 'hervorrufen, sondern hierbei gleichzeitig ein Kolloid bilden. Derartige Stoffe sind hydrolytisch spaltbare Aluminiumsalze; wie z. B. schwefelsaures, essigsaures oder ameisensaures Aluminium. Sie setzen sich mit Alkalikarbonaten derartig um, daß einerseits Kohlensäure entwickelt wird, anderseits Aluminiumhydroxyd' i'n kolloidaler Form entsteht. Das gebildete kolloidaleAluminium= hydroxyd trägt zu der Bildung des stehenbleibenden oder lang anhaltenden Schaumes bei. Zu der brausenden Mischung gibt man noch andere Kolloide, z. B. Gelatine, Eiweiß, Dextrin o. dgl.; und erreicht den Vorteil, daß wesentlich geringere Mengen der Zusätze notwendig sind; als sie beispielsweise bei Mischungen aus Weinsäure und Bikarbonat notwendig wären.The present method consists in that for the preparation of the effervescent or gas-evolving mixture used substances with the second Part of not just the creation of a. Foam or the development of gas 'but at the same time form a colloid. Such substances are hydrolytically cleavable aluminum salts; such as B. sulfuric acid, acetic acid or formic aluminum. They react with alkali carbonates in such a way that that on the one hand carbonic acid is developed, on the other hand aluminum hydroxide is more colloidal Form emerges. The colloidal aluminum hydroxide formed contributes to the formation the lingering or long-lasting foam. To the effervescent mixture there are other colloids, e.g. B. gelatin, egg white, dextrin or the like; and achieved the advantage that much smaller amounts of the additives are necessary; as they would be necessary, for example, with mixtures of tartaric acid and bicarbonate.
Der Vorteil der Verwendung des Aluminiumsulfates besteht darin, daß die Herstellung der Mischungen leichter ist, da die Verwendung größerer Mengen von Gelatine und Eiweiß immer gewisse technische Schwierigkeiten herbeiführt. Außerdem sind die Mischungen haltbarer, da schwefelsaures Aluminium ein Desinfektionsmittel ist und Zersetzungen vermeidet.The advantage of using the aluminum sulfate is that the preparation of the mixtures is easier, since the use of larger quantities of Gelatin and egg white always cause certain technical difficulties. aside from that the mixtures are more durable, since sulfuric aluminum is a disinfectant and avoids decomposition.
Zur Desinfektion von Körperhöhlen eignet sich beispielsweise folgende Mischung: 30 g Aluminiumsulfat, 3o g Natriumbilcarbonat, i g Gelatine, i g Sublimat bzw. Salizylsäure, z g Talk, 36g Milchzucker.For example, the following mixture is suitable for disinfecting body cavities: 30 g aluminum sulfate, 30 g sodium carbonate, 1 g gelatine, 1 g sublimate or salicylic acid, 1 g talc, 36 g lactose.
Die Zusätze von Talk und Milchzucker können auch fehlen.The additives of talc and lactose can also be missing.
Zur Erzielung brausender Mischungen hat man bereits Mischungen von Aluminiumsalzen mit weinsauren Salzen und Natriumbikarbonat vorgeschlagen. Die vorgeschriebene Gegenwart weinsaurer Salze verhindert hierbei die Niederschlagung von Aluminiumhy droxy d. Es entsteht eine klare Lösung; was ausdrücklich beabsichtigt war. Im Gegensatz hierzu wird bei . dem vorliegenden Verfahren absichtlich die Bildung von ungelöstem Aluminiumhydroxyd herbeigeführt. Die Aluminiumsalze haben noch den weiteren Vorteil, eine therapeutische Wirkung herbeizuführen.Mixtures of Aluminum salts with tartaric salts and sodium bicarbonate are suggested. The prescribed The presence of tartrate salts prevents the precipitation of aluminum hy droxy d. A clear solution results; which was expressly intended. In contrast this is done at. the present process intentionally eliminates the formation of undissolved solids Aluminum hydroxide brought about. The aluminum salts still have that another advantage of bringing about a therapeutic effect.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEL52997D DE369080C (en) | 1921-04-28 | 1921-04-28 | Process for the production of carbonic acid developing mixtures for the treatment of wounds and body cavities |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEL52997D DE369080C (en) | 1921-04-28 | 1921-04-28 | Process for the production of carbonic acid developing mixtures for the treatment of wounds and body cavities |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE369080C true DE369080C (en) | 1923-02-14 |
Family
ID=7275076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DEL52997D Expired DE369080C (en) | 1921-04-28 | 1921-04-28 | Process for the production of carbonic acid developing mixtures for the treatment of wounds and body cavities |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE369080C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5147339A (en) * | 1987-09-22 | 1992-09-15 | Coloplast A/S | Dressing material for the treatment of wounds, and corpuscles for use in the production thereof |
-
1921
- 1921-04-28 DE DEL52997D patent/DE369080C/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5147339A (en) * | 1987-09-22 | 1992-09-15 | Coloplast A/S | Dressing material for the treatment of wounds, and corpuscles for use in the production thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE369080C (en) | Process for the production of carbonic acid developing mixtures for the treatment of wounds and body cavities | |
| DE380699C (en) | Process for the treatment of cinematographic and photographic films | |
| DE930581C (en) | Hair care products | |
| DE492976C (en) | Process for the production of stable and storable, hydrogen sulfide-evolving preparations | |
| DE568339C (en) | Process for the production of a silver-containing preparation from ethylene diamine | |
| DE673163C (en) | Process for de-liming ashed hides and skins | |
| DE330816C (en) | Process for the preparation of colloidally soluble metal pyrophosphate casein compounds | |
| DE375717C (en) | Process for the preparation of derivatives of 3íñ3-diamino-4íñ4-dioxyarsenobenzene which are stable in solution | |
| DE549017C (en) | Process for the preservation of food with magnesium hydroxide | |
| DE379436C (en) | Process for the production of pharmaceuticals that split off sulphurous acid and colloidal sulfur | |
| DE454569C (en) | Process for the production of plant protection products | |
| DE419778C (en) | Process for the production of iron leather | |
| DE471675C (en) | Leather impregnation process | |
| DE469516C (en) | Process for the production of stable aqueous bismuth lactate solutions | |
| DE328341C (en) | Process for the preparation of basic tannic aluminum | |
| AT108132B (en) | Process for the separation of hafnium and zirconium. | |
| DE862129C (en) | Process to increase the sweetness of milk sugar or its hydrolyzate | |
| DE380195C (en) | Process for the pure preparation of gelatine | |
| DE403054C (en) | Process for the preparation of bismuth cacodylate | |
| DE929092C (en) | Process for the production of polyamide solutions | |
| DE688047C (en) | Process for the production of stable aqueous, therapeutically usable solutions of the polyoxyalkylisoalloxazines | |
| DE506635C (en) | Process for the decomposition of potassium magnesium carbonate double salts | |
| DE202468C (en) | ||
| AT85031B (en) | Process for the preparation of basic tannic aluminum. | |
| DE360689C (en) | Process for the preparation of a derivative of Phenylaethylhydantoin |