DE3687241T2 - Gewebetumorwachstumsinhibitoren, verfahren zur herstellung und verwendungen. - Google Patents

Gewebetumorwachstumsinhibitoren, verfahren zur herstellung und verwendungen.

Info

Publication number
DE3687241T2
DE3687241T2 DE8686105211T DE3687241T DE3687241T2 DE 3687241 T2 DE3687241 T2 DE 3687241T2 DE 8686105211 T DE8686105211 T DE 8686105211T DE 3687241 T DE3687241 T DE 3687241T DE 3687241 T2 DE3687241 T2 DE 3687241T2
Authority
DE
Germany
Prior art keywords
acidified
ethanol extract
tissue
derived
tgi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686105211T
Other languages
English (en)
Other versions
DE3687241D1 (de
Inventor
Kenneth K Iwata
John R Stephenson
Leslie I Gold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OSI Pharmaceuticals LLC
Original Assignee
Oncogene Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogene Science Inc filed Critical Oncogene Science Inc
Application granted granted Critical
Publication of DE3687241D1 publication Critical patent/DE3687241D1/de
Publication of DE3687241T2 publication Critical patent/DE3687241T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE8686105211T 1985-04-19 1986-04-15 Gewebetumorwachstumsinhibitoren, verfahren zur herstellung und verwendungen. Expired - Lifetime DE3687241T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72500385A 1985-04-19 1985-04-19
US84793186A 1986-04-07 1986-04-07

Publications (2)

Publication Number Publication Date
DE3687241D1 DE3687241D1 (de) 1993-01-21
DE3687241T2 true DE3687241T2 (de) 1993-07-01

Family

ID=27111075

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686105211T Expired - Lifetime DE3687241T2 (de) 1985-04-19 1986-04-15 Gewebetumorwachstumsinhibitoren, verfahren zur herstellung und verwendungen.

Country Status (10)

Country Link
EP (1) EP0200090B1 (de)
JP (1) JPH0788397B2 (de)
AT (1) ATE83152T1 (de)
AU (1) AU600230B2 (de)
CA (1) CA1274471A (de)
DE (1) DE3687241T2 (de)
ES (1) ES8800960A1 (de)
IE (1) IE60059B1 (de)
IL (1) IL78546A0 (de)
NZ (1) NZ215887A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886747A (en) * 1985-03-22 1989-12-12 Genentech, Inc. Nucleic acid encoding TGF-β and its uses
US5284763A (en) * 1985-03-22 1994-02-08 Genentech, Inc. Nucleic acid encoding TGF-β and its uses
NZ222168A (en) * 1986-10-20 1991-05-28 Oncogene Science Inc Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions
DE3907822A1 (de) * 1989-03-10 1990-09-13 Adolf Dr Loefflmann Verwendung einer peroxidaseaktivitaet zeigenden proteinfraktion aus dem photosyntheseapparat von pflanzen als arzneimittel, insbesondere zur krebsbekaempfung, sowie verfahren zur gewinnung einer proteinmischung und arzneimittel zur krebsbekaempfung
GB9106678D0 (en) * 1991-03-28 1991-05-15 Ferguson Mark W J Wound healing
RU2065307C1 (ru) * 1994-12-13 1996-08-20 Александр Васильевич Тихонов Способ лечения первичного рака печени и набор для лечения первичного рака печени
JP2002539172A (ja) 1999-03-17 2002-11-19 ノバルティス アクチエンゲゼルシャフト Ｔｇｆ−ベータを含む医薬組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5221570B2 (de) * 1973-08-30 1977-06-11
WO1984004924A1 (en) * 1983-06-03 1984-12-20 Us Commerce Purified transforming growth factor-beta derived from human platelets and placentas
US4524026A (en) * 1983-08-29 1985-06-18 Yoshio Sakagami Novel proteinous cancer-cell proliferation inhibitory factors

Also Published As

Publication number Publication date
ES8800960A1 (es) 1987-12-01
EP0200090B1 (de) 1992-12-09
IE860971L (en) 1986-10-19
EP0200090A2 (de) 1986-11-05
CA1274471A (en) 1990-09-25
ATE83152T1 (de) 1992-12-15
AU5644486A (en) 1986-10-23
EP0200090A3 (en) 1988-05-04
NZ215887A (en) 1991-05-28
IE60059B1 (en) 1994-05-18
DE3687241D1 (de) 1993-01-21
JPS6223A (ja) 1987-01-06
JPH0788397B2 (ja) 1995-09-27
IL78546A0 (en) 1986-08-31
AU600230B2 (en) 1990-08-09
ES554177A0 (es) 1987-12-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: DERZEIT KEIN VERTRETER BESTELLT

8327 Change in the person/name/address of the patent owner

Owner name: OSI PHARMACEUTICALS,INC.(N.D.GES.D.STAATES DELAWAR