DE3683368D1 - Ein in der erfassung und in der identifizierung von aktivierten t-lymphozyten zu verwendendes polypeptid. - Google Patents

Ein in der erfassung und in der identifizierung von aktivierten t-lymphozyten zu verwendendes polypeptid.

Info

Publication number
DE3683368D1
DE3683368D1 DE8686308172T DE3683368T DE3683368D1 DE 3683368 D1 DE3683368 D1 DE 3683368D1 DE 8686308172 T DE8686308172 T DE 8686308172T DE 3683368 T DE3683368 T DE 3683368T DE 3683368 D1 DE3683368 D1 DE 3683368D1
Authority
DE
Germany
Prior art keywords
lymphocytes
activated
polypeptide
identification
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686308172T
Other languages
English (en)
Inventor
Thorfinn Ege
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Nycomed AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed AS filed Critical Nycomed AS
Application granted granted Critical
Publication of DE3683368D1 publication Critical patent/DE3683368D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE8686308172T 1985-10-22 1986-10-21 Ein in der erfassung und in der identifizierung von aktivierten t-lymphozyten zu verwendendes polypeptid. Expired - Fee Related DE3683368D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858525974A GB8525974D0 (en) 1985-10-22 1985-10-22 Chemical substance

Publications (1)

Publication Number Publication Date
DE3683368D1 true DE3683368D1 (de) 1992-02-20

Family

ID=10587035

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686308172T Expired - Fee Related DE3683368D1 (de) 1985-10-22 1986-10-21 Ein in der erfassung und in der identifizierung von aktivierten t-lymphozyten zu verwendendes polypeptid.

Country Status (8)

Country Link
US (1) US4832940A (de)
EP (1) EP0236619B1 (de)
JP (1) JP2727074B2 (de)
AT (1) ATE71306T1 (de)
DE (1) DE3683368D1 (de)
ES (1) ES2040210T3 (de)
GB (1) GB8525974D0 (de)
NO (1) NO174326C (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5330896A (en) * 1983-02-24 1994-07-19 Billing Ronald J Monoclonal antibodies to an autocrine growth factor antigen that binds to activated lymphocytes and cancer cells
WO1987002893A1 (en) * 1985-11-18 1987-05-21 Board Of Regents, The University Of Texas System Polychelating agents for image and spectral enhancement (and spectral shift)
US5679323A (en) * 1986-07-03 1997-10-21 Advanced Magnetics, Inc. Hepatocyte-specific receptor-mediated endocytosis-type compositions
US5352432A (en) * 1986-07-03 1994-10-04 Advanced Magnetics, Inc. Hepatocyte specific composition and their use as diagnostic imaging agents
US5342607A (en) * 1986-07-03 1994-08-30 Advanced Magnetics, Inc. Receptor mediated endocytosis type magnetic resonance imaging contrast agents
US6461825B1 (en) * 1987-09-30 2002-10-08 Sanofi (Societe Anonyme) Immunometric assay kit and method applicable to whole cells
WO1990001295A1 (en) * 1988-08-04 1990-02-22 Advanced Magnetics, Incorporated Receptor mediated endocytosis type mri contrast agents
US4986979A (en) * 1989-03-14 1991-01-22 Neorx Corporation Imaging tissue sites of inflammation
US5686410A (en) * 1989-07-20 1997-11-11 Novartis Ag Polypeptide derivatives
EP0485664A1 (de) * 1990-11-13 1992-05-20 Mallinckrodt Diagnostica (Holland) B.V. Verfahren zur Herstellung von einem diagnostischen Mittel zur Feststellung von Entzündungen
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
US5997844A (en) * 1991-02-08 1999-12-07 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
US5508020A (en) 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
US5346686A (en) * 1992-10-05 1994-09-13 Mallinckrodt Medical, Inc. Labelled interleukin-8 and medical uses thereof
US5605671A (en) * 1992-10-05 1997-02-25 The Regents Of The University Of Michigan Radiolabeled neutrophil activating peptides for imaging
WO1994009128A1 (en) * 1992-10-22 1994-04-28 Mallinckrodt Medical, Inc. Therapeutic treatment for inhibiting vascular restenosis
US5951964A (en) * 1993-06-04 1999-09-14 Diatide, Inc. Technetium-99m labeled peptides for imaging
US6008319A (en) * 1996-12-23 1999-12-28 University Of Southern California Vasopermeability enhancing peptide of human interleukin-2 and immunoconjugates thereof
US7067111B1 (en) * 1999-10-25 2006-06-27 Board Of Regents, University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
EP1286704B1 (de) * 2000-06-02 2014-07-23 Board of Regents, The University of Texas System ETHYLENEDICYSTEINE (EC)-Glucose Analoge KONJUGATE
ITRM20030159A1 (it) * 2003-04-07 2004-10-08 Uni Degli Studi Di Roma L A Sapienza Citochine radiomarcate e loro usi come traccianti scintigrafici per la visualizzazione delle infiammazioni croniche linfocito-mediate.
US9050378B2 (en) * 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
US8758723B2 (en) 2006-04-19 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
WO2007143698A2 (en) * 2006-06-06 2007-12-13 Rutgers, The State University Of New Jersey Iodinated polymers
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
IT201900011013A1 (it) 2019-07-05 2021-01-05 Sapienza Univ Di Roma Composto e composizione radiofarmaceutici per l’imaging con tecnica di Tomografia a Emissione di Positroni (PET) di cellule positive al recettore dell’interleuchina-2, processo per la loro preparazione, relativo kit e loro usi.

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472371A (en) * 1979-10-29 1984-09-18 Summa Medical Corporation Radiolabeled antibody to anti-tumor associated antigen and process
AU556548B2 (en) * 1980-03-03 1986-11-06 Milton David Goldenberg Tumor localization and therapy with labeled antibodies and antibody fragments specific to tumor-associated markers
US4473493A (en) * 1981-04-29 1984-09-25 Immunex Corporation Hybridoma antibody which inhibits interleukin 2 activity
US4454106A (en) * 1982-06-07 1984-06-12 Gansow Otto A Use of metal chelate conjugated monoclonal antibodies
US4443427A (en) * 1982-06-21 1984-04-17 Sidney Farber Cancer Institute, Inc. Monoclonal antibody
JPS59116231A (ja) * 1982-12-13 1984-07-05 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ 抗−インタ−ロイキン−２単クロ−ン抗体
US4550086A (en) * 1983-02-16 1985-10-29 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies that recognize human T cells
ATE61000T1 (de) * 1983-07-29 1991-03-15 Milton David Goldenberg Verfahren zur erhoehung der zielspezifizitaet in antikoerperbestimmungen und zur raeumung von nichtzielspezifischen diagnostischen und therapeutischen faktoren.
US4578335A (en) * 1984-05-21 1986-03-25 Immunex Corporation Interleukin 2 receptor
US4634586A (en) * 1984-05-21 1987-01-06 The Board Of Trustees Of The Leland Stanford Junior University Reagent and method for radioimaging leukocytes
US4695538A (en) * 1984-06-01 1987-09-22 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies to cell surface antigens
CA1260827A (en) * 1984-08-31 1989-09-26 Richard C. Siegel Antibody-metal ion complexes

Also Published As

Publication number Publication date
US4832940A (en) 1989-05-23
EP0236619A1 (de) 1987-09-16
ATE71306T1 (de) 1992-01-15
ES2040210T3 (es) 1993-10-16
JPS62187498A (ja) 1987-08-15
NO174326C (no) 1994-04-20
GB8525974D0 (en) 1985-11-27
EP0236619B1 (de) 1992-01-08
JP2727074B2 (ja) 1998-03-11
NO174326B (no) 1994-01-10
NO864203D0 (no) 1986-10-21
NO864203L (no) 1987-04-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee