DE3683178D1 - Methode zur herstellung monoklonaler antikoerper gegen plasminogenaktivatorfaktor. - Google Patents
Methode zur herstellung monoklonaler antikoerper gegen plasminogenaktivatorfaktor.Info
- Publication number
- DE3683178D1 DE3683178D1 DE8686302236T DE3683178T DE3683178D1 DE 3683178 D1 DE3683178 D1 DE 3683178D1 DE 8686302236 T DE8686302236 T DE 8686302236T DE 3683178 T DE3683178 T DE 3683178T DE 3683178 D1 DE3683178 D1 DE 3683178D1
- Authority
- DE
- Germany
- Prior art keywords
- monoclonal antibodies
- antibodies against
- plasminogen activator
- producing monoclonal
- activator factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000001938 Plasminogen Activators Human genes 0.000 title 1
- 108010001014 Plasminogen Activators Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940127126 plasminogen activator Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60061716A JPS61221128A (ja) | 1985-03-26 | 1985-03-26 | プラスミノ−ゲン活性化因子に対するモノクロ−ナル抗体とその調製方法及び該モノクロ−ナル抗体の使用方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3683178D1 true DE3683178D1 (de) | 1992-02-13 |
Family
ID=13179228
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686302236T Expired - Lifetime DE3683178D1 (de) | 1985-03-26 | 1986-03-26 | Methode zur herstellung monoklonaler antikoerper gegen plasminogenaktivatorfaktor. |
Country Status (5)
Country | Link |
---|---|
US (1) | US5112754A (de) |
EP (1) | EP0196226B1 (de) |
JP (1) | JPS61221128A (de) |
CA (1) | CA1292708C (de) |
DE (1) | DE3683178D1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU7709287A (en) * | 1986-07-16 | 1988-02-10 | Celltech Limited | Process for purifying a plasminogen activator |
US4833085A (en) * | 1986-08-13 | 1989-05-23 | Monsanto Company | Monoclonal antibody specific for human colon fibroblast-derived t-PA |
AT388618B (de) * | 1987-05-05 | 1989-08-10 | Binder Bernd Dr | Verfahren zur quantitativen bestimmung von funktion und antigener konzentration einer in einer biologischen fluessigkeit enthaltenen substanz |
US5225540A (en) * | 1988-04-26 | 1993-07-06 | Du Pont Merck Pharmaceutical Company | Monoclonal antibodies to tissue plasminogen activator (t-pa) which prolong its functional half-life |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3222084A1 (de) * | 1982-06-11 | 1983-12-15 | Bayer Ag, 5090 Leverkusen | Monoklonale antikoerper |
JPS5951220A (ja) * | 1982-08-02 | 1984-03-24 | Asahi Chem Ind Co Ltd | 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤 |
FR2548211B1 (fr) * | 1983-06-29 | 1985-10-18 | Choay Sa | Procede de production d'un activateur tissulaire du plasminogene et activateur obtenu par ce procede |
DE3584902D1 (de) * | 1984-02-29 | 1992-01-30 | Asahi Chemical Ind | Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren. |
EP0190711B1 (de) * | 1985-02-07 | 1989-04-26 | Kowa Company, Ltd. | Monoklonale Antikörper gegen den Gewebeplasminogenaktivator von normalen menschlichen Zellen |
US4889808A (en) * | 1985-10-01 | 1989-12-26 | American Home Products | Method of enchancing t-PA and SCU-PA production |
-
1985
- 1985-03-26 JP JP60061716A patent/JPS61221128A/ja active Pending
-
1986
- 1986-03-21 CA CA000504690A patent/CA1292708C/en not_active Expired - Lifetime
- 1986-03-26 EP EP86302236A patent/EP0196226B1/de not_active Expired
- 1986-03-26 DE DE8686302236T patent/DE3683178D1/de not_active Expired - Lifetime
-
1990
- 1990-02-23 US US07/483,800 patent/US5112754A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5112754A (en) | 1992-05-12 |
JPS61221128A (ja) | 1986-10-01 |
EP0196226B1 (de) | 1992-01-02 |
EP0196226A3 (en) | 1988-04-20 |
EP0196226A2 (de) | 1986-10-01 |
CA1292708C (en) | 1991-12-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |