DE3675328D1 - Anorganisches saures salz von n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanylchlorid und verfahren zu seiner herstellung. - Google Patents

Anorganisches saures salz von n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanylchlorid und verfahren zu seiner herstellung.

Info

Publication number
DE3675328D1
DE3675328D1 DE8686111689T DE3675328T DE3675328D1 DE 3675328 D1 DE3675328 D1 DE 3675328D1 DE 8686111689 T DE8686111689 T DE 8686111689T DE 3675328 T DE3675328 T DE 3675328T DE 3675328 D1 DE3675328 D1 DE 3675328D1
Authority
DE
Germany
Prior art keywords
phenylpropyl
ethoxycarbonyl
production
acid salt
inorganic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686111689T
Other languages
English (en)
Inventor
Kazuhiko Yamada
Yoshifumi Yanagida
Satomi Takahashi
Takehisa Ohashi
Kiyoshi Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Application granted granted Critical
Publication of DE3675328D1 publication Critical patent/DE3675328D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8686111689T 1985-08-27 1986-08-23 Anorganisches saures salz von n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanylchlorid und verfahren zu seiner herstellung. Expired - Lifetime DE3675328D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60188242A JPS6248655A (ja) 1985-08-27 1985-08-27 Ｎ−〔１（ｓ）−エトキシカルボニル−３−フエニルプロピル〕−ｌ−アラニルクロリド無機酸塩及びその製造法

Publications (1)

Publication Number Publication Date
DE3675328D1 true DE3675328D1 (de) 1990-12-06

Family

ID=16220273

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686111689T Expired - Lifetime DE3675328D1 (de) 1985-08-27 1986-08-23 Anorganisches saures salz von n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanylchlorid und verfahren zu seiner herstellung.

Country Status (7)

Country Link
US (1) US4760162A (de)
EP (1) EP0219651B1 (de)
JP (1) JPS6248655A (de)
CA (1) CA1261344A (de)
DE (1) DE3675328D1 (de)
ES (1) ES2000879A6 (de)
IE (1) IE59257B1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6300361B1 (en) * 1990-07-25 2001-10-09 Novartis Ag Stabilized pharmaceutical compositions comprising acid donors
EP2207768A1 (de) * 2007-11-13 2010-07-21 DSM IP Assets B.V. Verbesserte ramipiril-synthese

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2126180A (en) * 1929-01-16 1938-08-09 Parke Davis & Co Ureido n-diaryl dicarboxylic acid halides
US2099781A (en) * 1933-10-27 1937-11-23 Du Pont Halogenation process and product
GB1241844A (en) * 1968-08-23 1971-08-04 Beecham Group Ltd Penicillins
EP0018546B1 (de) * 1979-04-25 1983-09-28 BIOCHEMIE Gesellschaft m.b.H. Verfahren zur Herstellung von Phenylglycyl-chlorid-hydrochloriden
DE3276311D1 (en) * 1981-02-17 1987-06-19 Warner Lambert Co Octahydro-2-(omega-mercaptoalkanoyl)3-oxo-1h-isoindole-1-carboxylic acids and esters
US4532342A (en) * 1981-02-20 1985-07-30 Warner-Lambert Company N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4556652A (en) * 1984-03-02 1985-12-03 Usv Pharmaceutical Corp. Antihypertensive spiro-amidoamino compounds
JPS6248696A (ja) * 1985-08-27 1987-03-03 Kanegafuchi Chem Ind Co Ltd Ｎ−〔１（ｓ）−エトキシカルボニル−３−フエニルプロピル〕−ｌ−アラニル−ｌ−プロリンの製造法

Also Published As

Publication number Publication date
IE862246L (en) 1987-02-27
IE59257B1 (en) 1994-01-26
EP0219651A1 (de) 1987-04-29
JPH0333149B2 (de) 1991-05-16
EP0219651B1 (de) 1990-10-31
JPS6248655A (ja) 1987-03-03
ES2000879A6 (es) 1988-03-16
US4760162A (en) 1988-07-26
CA1261344A (en) 1989-09-26

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