DE3671890D1 - Benzylaminoxidaseinhibitoren, selektiv in beziehung auf andere aminoxidasen. - Google Patents

Benzylaminoxidaseinhibitoren, selektiv in beziehung auf andere aminoxidasen.

Info

Publication number
DE3671890D1
DE3671890D1 DE8686830054T DE3671890T DE3671890D1 DE 3671890 D1 DE3671890 D1 DE 3671890D1 DE 8686830054 T DE8686830054 T DE 8686830054T DE 3671890 T DE3671890 T DE 3671890T DE 3671890 D1 DE3671890 D1 DE 3671890D1
Authority
DE
Germany
Prior art keywords
sup
groups
selective
aminoxidases
relating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686830054T
Other languages
English (en)
Inventor
Vincenzo Bertini
Munno Angela De
Francesco Lucchesini
Franca Buffoni
Barbara Bertocci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consiglio Nazionale delle Richerche CNR
Original Assignee
Consiglio Nazionale delle Richerche CNR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale delle Richerche CNR filed Critical Consiglio Nazionale delle Richerche CNR
Application granted granted Critical
Publication of DE3671890D1 publication Critical patent/DE3671890D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DE8686830054T 1985-04-01 1986-03-10 Benzylaminoxidaseinhibitoren, selektiv in beziehung auf andere aminoxidasen. Expired - Fee Related DE3671890D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47906/85A IT1181871B (it) 1985-04-01 1985-04-01 Inibitori selettivi delle benzilamminossidasi rispetto ad altre amminossidasi

Publications (1)

Publication Number Publication Date
DE3671890D1 true DE3671890D1 (de) 1990-07-19

Family

ID=11263264

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198686830054T Pending DE210140T1 (de) 1985-04-01 1986-03-10 Benzylaminoxidaseinhibitoren, selektiv in beziehung auf andere aminoxidasen.
DE8686830054T Expired - Fee Related DE3671890D1 (de) 1985-04-01 1986-03-10 Benzylaminoxidaseinhibitoren, selektiv in beziehung auf andere aminoxidasen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE198686830054T Pending DE210140T1 (de) 1985-04-01 1986-03-10 Benzylaminoxidaseinhibitoren, selektiv in beziehung auf andere aminoxidasen.

Country Status (7)

Country Link
US (1) US4888283A (de)
EP (1) EP0210140B1 (de)
JP (1) JPS61239891A (de)
AT (1) ATE53569T1 (de)
CA (1) CA1303045C (de)
DE (2) DE210140T1 (de)
IT (1) IT1181871B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5444042A (en) * 1990-12-28 1995-08-22 Cortex Pharmaceuticals Method of treatment of neurodegeneration with calpain inhibitors
JP2004536064A (ja) * 2001-01-23 2004-12-02 ピーアンドジー−クレイロール・インコーポレイテッド 酸化毛髪染色において使用する新規のカップラー
AR042941A1 (es) 2003-01-27 2005-07-06 Fujisawa Pharmaceutical Co Derivados de tiazol, su preparacion, composiciones farmaceuticas que los contienen y su uso en la fabricacion de medicamentos inhibidores de la proteina-1 de adhesion vascular (vap-1)
US20060229346A1 (en) * 2003-03-31 2006-10-12 Sucampo Ag Method for treating vascular hyperpermeable disease
EP1786792B1 (de) * 2004-07-27 2009-04-08 Astellas Pharma Inc. Thiazolderivate mit vap-1-hemmender wirkung
CA2579889A1 (en) * 2004-09-09 2006-03-16 Astellas Pharma Inc. Thiazole derivatives having vap-1 inhibitory activity
TWI437986B (zh) 2008-01-31 2014-05-21 R Tech Ueno Ltd 噻唑衍生物及使用該衍生物作為ｖａｐ－１抑制劑之用途
TWI490214B (zh) 2008-05-30 2015-07-01 艾德克 上野股份有限公司 苯或噻吩衍生物及該等作為ｖａｐ－１抑制劑之用途
TW201116276A (en) 2009-09-16 2011-05-16 Astellas Pharma Inc Glycine compounds
HUE034860T2 (en) 2011-03-15 2018-03-28 Astellas Pharma Inc Guanidin Compound
JP2018076236A (ja) 2015-06-05 2018-05-17 株式会社アールテック・ウエノ がんを処置するための医薬組成物
MX2020002441A (es) * 2017-09-05 2020-09-03 Mti Biotech Inc Composiciones y metodos de uso de depuradores de gammacetoaldehido para tratar, prevenir o mejorar fibrosis del higado.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1989093A (en) * 1929-05-02 1935-01-29 Sharp & Dohme Inc Amino alcohols and the production thereof
US2553441A (en) * 1947-03-29 1951-05-15 Universal Oil Prod Co Stabilization of organic materials
US3070628A (en) * 1959-08-04 1962-12-25 Upjohn Co 4-allyloxybenzylamines
US3320314A (en) * 1964-01-22 1967-05-16 Sandoz Ag Chlorobenzyl sulfamides
US3399226A (en) * 1965-10-22 1968-08-27 Merck & Co Inc Preparation of phenylalanine compounds
DE1543388B1 (de) * 1966-12-23 1970-10-01 Boehringer Mannheim Gmbh Basisch substituierte,tricyclische heterocyclische Verbindungen und deren pharmakologisch nicht giftige Salze sowie Verfahren zu ihrer Herstellung
US4073942A (en) * 1972-10-23 1978-02-14 Boehringer Ingelheim Gmbh Halo-substituted hydroxybenzyl-amines as secretolytic agents
US3951970A (en) * 1973-10-01 1976-04-20 Sharps Associates Resorcinol amine derivatives
US3960958A (en) * 1974-08-26 1976-06-01 Pfizer Inc. 3,4- AND 3,5-Dialkoxybenzylamines
US4014937A (en) * 1974-08-26 1977-03-29 Pfizer Inc. 3,4-And 3,5-dialkoxyphenethylamines
US4388250A (en) * 1982-03-15 1983-06-14 Rhone Poulenc Inc. Process for the preparation of p-hydroxy-benzyl-nitriles and corresponding amines

Also Published As

Publication number Publication date
EP0210140A2 (de) 1987-01-28
EP0210140A3 (en) 1987-05-27
US4888283A (en) 1989-12-19
JPS61239891A (ja) 1986-10-25
IT1181871B (it) 1987-09-30
ATE53569T1 (de) 1990-06-15
EP0210140B1 (de) 1990-06-13
IT8547906A0 (it) 1985-04-01
CA1303045C (en) 1992-06-09
DE210140T1 (de) 1987-07-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee