DE3667175D1 - Cardiotonische heterocyclocarbonyl- und acetyl-thiazolone. - Google Patents

Cardiotonische heterocyclocarbonyl- und acetyl-thiazolone.

Info

Publication number
DE3667175D1
DE3667175D1 DE8686110452T DE3667175T DE3667175D1 DE 3667175 D1 DE3667175 D1 DE 3667175D1 DE 8686110452 T DE8686110452 T DE 8686110452T DE 3667175 T DE3667175 T DE 3667175T DE 3667175 D1 DE3667175 D1 DE 3667175D1
Authority
DE
Germany
Prior art keywords
heterocyclocarbonyl
thiazolone
cardiotonic
acetyl
cardiotonic heterocyclocarbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686110452T
Other languages
English (en)
Inventor
J Martin Grisar
Richard C Dage
Richard A Schnettler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of DE3667175D1 publication Critical patent/DE3667175D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE8686110452T 1985-10-15 1986-07-29 Cardiotonische heterocyclocarbonyl- und acetyl-thiazolone. Expired - Fee Related DE3667175D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/787,225 US4623651A (en) 1985-10-15 1985-10-15 Cardiotonic heterocyclocarbonyl- and acetyl-thiazolones

Publications (1)

Publication Number Publication Date
DE3667175D1 true DE3667175D1 (de) 1990-01-04

Family

ID=25140796

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686110452T Expired - Fee Related DE3667175D1 (de) 1985-10-15 1986-07-29 Cardiotonische heterocyclocarbonyl- und acetyl-thiazolone.

Country Status (21)

Country Link
US (1) US4623651A (de)
EP (1) EP0219625B1 (de)
JP (1) JPS6287586A (de)
KR (1) KR890005203B1 (de)
CN (1) CN1020730C (de)
AR (1) AR243887A1 (de)
AT (1) ATE48275T1 (de)
AU (1) AU588900B2 (de)
CA (1) CA1287833C (de)
DE (1) DE3667175D1 (de)
DK (1) DK368986A (de)
ES (1) ES2000594A6 (de)
FI (1) FI863159A (de)
GR (1) GR862045B (de)
HU (1) HU197004B (de)
IL (1) IL79343A0 (de)
NO (1) NO863113L (de)
NZ (1) NZ217068A (de)
PH (1) PH22193A (de)
PT (1) PT83137B (de)
ZA (1) ZA865839B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927939A (en) * 1985-10-15 1990-05-22 Merrell Dow Pharmaceuticals Cardiotonic aroylthiazolones
US4734422A (en) * 1985-10-15 1988-03-29 Merrell Dow Pharmaceuticals Inc. Cardiotonic aroylthiazolones and the use thereof
US4762849A (en) * 1985-10-15 1988-08-09 Merrell Dow Pharmaceuticals Inc. Cardiotonic alkanoylthiazolones
US4670450A (en) * 1985-11-13 1987-06-02 Merrell Dow Pharmaceuticals Inc. Cardiotonic thiazolones
US4868182A (en) * 1986-11-05 1989-09-19 Merrell Dow Pharmaceuticals Inc. Enhancement of prazosin
US4866182A (en) * 1988-02-18 1989-09-12 Merrell Dow Pharmaceuticals Inc. Cardiotonic alkanoyl and aroyl oxazolones
US5095028A (en) * 1988-01-14 1992-03-10 Kureha Kagaku Kogyo Kabushiki Kaisha 2-(4-chlorobenzyl)-1-(1H-imidazole-1-ylmethyl)-1-cyclohexanol and cycloheptanol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3514465A (en) * 1966-12-30 1970-05-26 Degussa Certain thiazolyl- and pyridinylaminoketones
FR2209560A1 (en) * 1972-12-07 1974-07-05 Degussa N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin

Also Published As

Publication number Publication date
PH22193A (en) 1988-06-28
GR862045B (en) 1986-12-24
JPS6287586A (ja) 1987-04-22
DK368986A (da) 1987-04-16
ATE48275T1 (de) 1989-12-15
NO863113D0 (no) 1986-08-01
CN1020730C (zh) 1993-05-19
DK368986D0 (da) 1986-08-01
NZ217068A (en) 1989-01-27
AR243887A1 (es) 1993-09-30
NO863113L (no) 1987-04-21
ES2000594A6 (es) 1988-03-01
PT83137B (pt) 1988-07-29
ZA865839B (en) 1987-03-25
AU6084286A (en) 1987-04-16
KR870004025A (ko) 1987-05-07
KR890005203B1 (ko) 1989-12-18
EP0219625A1 (de) 1987-04-29
PT83137A (en) 1986-09-01
IL79343A0 (en) 1986-10-31
EP0219625B1 (de) 1989-11-29
CN86104968A (zh) 1987-04-22
CA1287833C (en) 1991-08-20
AU588900B2 (en) 1989-09-28
HUT44785A (en) 1988-04-28
HU197004B (en) 1989-02-28
FI863159A (fi) 1987-04-16
US4623651A (en) 1986-11-18
FI863159A0 (fi) 1986-08-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee