DE3664044D1 - N,n-dialkylaminoalkyl-hexahydro-5-oxo-1h-pyrrolizine-3-carboxamides - Google Patents

N,n-dialkylaminoalkyl-hexahydro-5-oxo-1h-pyrrolizine-3-carboxamides

Info

Publication number
DE3664044D1
DE3664044D1 DE8686113086T DE3664044T DE3664044D1 DE 3664044 D1 DE3664044 D1 DE 3664044D1 DE 8686113086 T DE8686113086 T DE 8686113086T DE 3664044 T DE3664044 T DE 3664044T DE 3664044 D1 DE3664044 D1 DE 3664044D1
Authority
DE
Germany
Prior art keywords
pyrrolizine
dialkylaminoalkyl
carboxamides
hexahydro
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8686113086T
Other languages
English (en)
Inventor
Donald E Butler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of DE3664044D1 publication Critical patent/DE3664044D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
DE8686113086T 1985-09-24 1986-09-23 N,n-dialkylaminoalkyl-hexahydro-5-oxo-1h-pyrrolizine-3-carboxamides Expired DE3664044D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/779,712 US4638006A (en) 1985-09-24 1985-09-24 Amnesia reversal with N,N-dialkylaminoalkyl-hexahydro-5-oxo 1H-pyrrolizine-3-carboxamides

Publications (1)

Publication Number Publication Date
DE3664044D1 true DE3664044D1 (de) 1989-07-27

Family

ID=25117290

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686113086T Expired DE3664044D1 (de) 1985-09-24 1986-09-23 N,n-dialkylaminoalkyl-hexahydro-5-oxo-1h-pyrrolizine-3-carboxamides

Country Status (5)

Country Link
US (1) US4638006A (de)
EP (1) EP0219706B1 (de)
JP (1) JPS6272690A (de)
AT (1) ATE44149T1 (de)
DE (1) DE3664044D1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE864269A (fr) * 1977-03-03 1978-06-16 Parke Davis & Co Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides et procedes pour les produire
JPS58159493A (ja) * 1982-03-16 1983-09-21 Suntory Ltd ８−置換ピロリチジン誘導体およびその用途
US4551470A (en) * 1983-08-29 1985-11-05 Warner-Lambert Company Hexahydro-3,5-dioxo-1H-pyrrolizine-2-carboxylic acid and derivatives, and use for reversing electroconvulsive shock amnesia
US4563469A (en) * 1984-07-20 1986-01-07 Warner-Lambert Company Derivatives of N-[2-(tetrahydro-3,5-dioxo-1H-pyrrolizin-7a(5H)-yl)ethyl]amine as cognition activators

Also Published As

Publication number Publication date
US4638006A (en) 1987-01-20
EP0219706A1 (de) 1987-04-29
ATE44149T1 (de) 1989-07-15
EP0219706B1 (de) 1989-06-21
JPS6272690A (ja) 1987-04-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee