DE3583083D1 - Pharmazeutische mikroemulsionen des oel-in-wasser-typs. - Google Patents

Pharmazeutische mikroemulsionen des oel-in-wasser-typs.

Info

Publication number
DE3583083D1
DE3583083D1 DE8585110009T DE3583083T DE3583083D1 DE 3583083 D1 DE3583083 D1 DE 3583083D1 DE 8585110009 T DE8585110009 T DE 8585110009T DE 3583083 T DE3583083 T DE 3583083T DE 3583083 D1 DE3583083 D1 DE 3583083D1
Authority
DE
Germany
Prior art keywords
oil
water type
microemulsions
pharmaceutical
pharmaceutical microemulsions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585110009T
Other languages
English (en)
Inventor
Yutaka Mizushima
Mitsuharu Fujii
Hiroshi Takei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Morishita Pharmaceuticals Co Ltd
Pfizer Japan Inc
Original Assignee
Morishita Pharmaceuticals Co Ltd
Lederle Japan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morishita Pharmaceuticals Co Ltd, Lederle Japan Ltd filed Critical Morishita Pharmaceuticals Co Ltd
Application granted granted Critical
Publication of DE3583083D1 publication Critical patent/DE3583083D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE8585110009T 1984-08-10 1985-08-08 Pharmazeutische mikroemulsionen des oel-in-wasser-typs. Expired - Lifetime DE3583083D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59166612A JPH0647533B2 (ja) 1984-08-10 1984-08-10 ４−ビフエニリル酢酸系化合物含有脂肪乳剤

Publications (1)

Publication Number Publication Date
DE3583083D1 true DE3583083D1 (de) 1991-07-11

Family

ID=15834533

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585110009T Expired - Lifetime DE3583083D1 (de) 1984-08-10 1985-08-08 Pharmazeutische mikroemulsionen des oel-in-wasser-typs.

Country Status (6)

Country Link
US (1) US4647586A (de)
EP (1) EP0171084B1 (de)
JP (1) JPH0647533B2 (de)
AU (1) AU583837B2 (de)
CA (1) CA1263604A (de)
DE (1) DE3583083D1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874588A (en) 1984-03-29 1989-10-17 Diatec Polymers Method and apparatus for rapidly dissolving polymers in water
IL78929A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Microemulsion compositions for parenteral administration
US4816247A (en) * 1985-09-11 1989-03-28 American Cyanamid Company Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs
US4784845A (en) * 1985-09-16 1988-11-15 American Cyanamid Company Emulsion compostions for the parenteral administration of sparingly water soluble ionizable hydrophobic drugs
JPS6348214A (ja) * 1986-08-18 1988-02-29 Morishita Seiyaku Kk １−〔２−（２，４−ジクロロフエニル）−３−メチル−１−ペンテニル〕−１ｈ−イミダゾ−ルを含有する水中油型脂肪乳剤
CA1338736C (fr) * 1986-12-05 1996-11-26 Roger Baurain Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation
GB2217596A (en) * 1988-04-26 1989-11-01 American Cyanamid Co Anti-arthritic liposome composition
JP2847783B2 (ja) * 1988-08-11 1999-01-20 日清製粉株式会社 抗癌活性増強剤
US5338761A (en) * 1988-09-29 1994-08-16 Shiseido Company Ltd. Emulsified composition
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
US5104656A (en) * 1989-06-16 1992-04-14 Seth Pyare L Percutaneous treatment with a high potency non-steroidal anti-inflammatory agent
US5032400A (en) * 1989-11-02 1991-07-16 Erie Laboratories Shark liver oil and garlic oil topical analgesic
JP2785981B2 (ja) * 1989-11-20 1998-08-13 株式会社資生堂 乳化組成物
US5635491A (en) * 1990-11-06 1997-06-03 Nippon Shinyaku Co., Ltd. Lyophilized fatty emulsions and a process for the production thereof
GB2260079B (en) * 1991-10-01 1995-08-09 American Cyanamid Co Pharmaceutical composition containing felbinac
IL101007A (en) * 1992-02-18 1997-08-14 Pharmos Ltd Dry stable compositions prepared by lyophilization
CA2130357A1 (en) * 1992-02-18 1993-08-19 Doron Friedman Dry compositions for preparing submicron emulsions
IL101241A (en) * 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
IL101387A (en) * 1992-03-26 1999-11-30 Pharmos Ltd Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets
JPH06157294A (ja) * 1992-11-19 1994-06-03 Tanabe Seiyaku Co Ltd 脂肪微粒子製剤
US6113921A (en) * 1993-03-23 2000-09-05 Pharmos Corp. Topical and transdermal delivery system utilizing submicron oil spheres
SE9303281D0 (sv) * 1993-10-07 1993-10-07 Astra Ab New formulation
US5961970A (en) * 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
ES2094688B1 (es) * 1994-08-08 1997-08-01 Cusi Lab Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion.
ES2277339T3 (es) * 1995-11-30 2007-07-01 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Vacuna con adyuvante de aceite y metodo para su preparacion.
ATE281835T1 (de) * 1996-08-07 2004-11-15 Kyowa Hakko Kogyo Kk Fettemulsion, die ein xanthinderivat enthält
EP1248628A4 (de) * 1999-12-14 2004-08-04 Sky High Llc PHOSPHOLIPID-ZUSAMMENSETZUNGEN ALS ENTZüNDUNGSHEMMER
CN100367951C (zh) * 2005-12-16 2008-02-13 石药集团恩必普药业有限公司 丁苯酞静脉乳剂及其应用
US9918934B2 (en) * 2006-12-12 2018-03-20 Edgar Joel Acosta-Zara Linker-based lecithin microemulsion delivery vehicles
US20090286832A1 (en) * 2008-05-15 2009-11-19 Kiichiro Nabeta Narcotic emulsion formulations for treatment of surgical pain
CN102333443A (zh) 2009-02-26 2012-01-25 帝国制药美国公司 治疗癌症疼痛的麻醉乳液制剂
MX2011012982A (es) 2009-06-05 2012-03-26 Sunev Pharma Solution Ltd Microemulsion topica para el tratamiento de trastornos reumaticos.
WO2012003441A1 (en) * 2010-07-02 2012-01-05 Isp Investments Inc. Self-emulsifying oil
CN111840553A (zh) * 2019-04-15 2020-10-30 湖州依诺唯新药物制剂有限公司 脂性药物制剂及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA725596A (en) * 1960-08-26 1966-01-11 J. Wretlind Arvid Method of preparing intravenously injectable fat emulsions free from side reactions or complications
NL6815027A (de) * 1967-10-26 1969-04-29
US4073943A (en) * 1974-09-11 1978-02-14 Apoteksvarucentralen Vitrum Ab Method of enhancing the administration of pharmalogically active agents
US4168308A (en) * 1976-03-12 1979-09-18 Apoteksvarucentralen Vitrum Ab Composition for enhancing the administration of pharmacologically active agents
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
JPS5933244A (ja) * 1982-08-20 1984-02-23 Nippon Redarii Kk ４−ビフエニリル酢酸エステル
JPS601122A (ja) * 1983-06-20 1985-01-07 Green Cross Corp:The ビフエニリルプロピオン酸誘導体脂肪乳剤

Also Published As

Publication number Publication date
CA1263604A (en) 1989-12-05
US4647586A (en) 1987-03-03
JPH0647533B2 (ja) 1994-06-22
AU583837B2 (en) 1989-05-11
EP0171084A2 (de) 1986-02-12
AU4585085A (en) 1986-02-13
EP0171084B1 (de) 1991-06-05
EP0171084A3 (en) 1987-04-08
JPS6144809A (ja) 1986-03-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee