DE3582608D1 - Verfahren und zell-linie zum erhalten von plasminogen-aktivatoren. - Google Patents

Verfahren und zell-linie zum erhalten von plasminogen-aktivatoren.

Info

Publication number
DE3582608D1
DE3582608D1 DE8585104260T DE3582608T DE3582608D1 DE 3582608 D1 DE3582608 D1 DE 3582608D1 DE 8585104260 T DE8585104260 T DE 8585104260T DE 3582608 T DE3582608 T DE 3582608T DE 3582608 D1 DE3582608 D1 DE 3582608D1
Authority
DE
Germany
Prior art keywords
receiving
cell line
plasminogen activators
plasminogen
activators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585104260T
Other languages
English (en)
Inventor
Sham Y Chan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Inc filed Critical Miles Inc
Application granted granted Critical
Publication of DE3582608D1 publication Critical patent/DE3582608D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/91—Cell lines ; Processes using cell lines
DE8585104260T 1984-04-19 1985-04-09 Verfahren und zell-linie zum erhalten von plasminogen-aktivatoren. Expired - Fee Related DE3582608D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60186884A 1984-04-19 1984-04-19
US06/704,593 US4757005A (en) 1984-04-19 1985-02-22 Method and cell line for obtaining plasminogen activators

Publications (1)

Publication Number Publication Date
DE3582608D1 true DE3582608D1 (de) 1991-05-29

Family

ID=27083979

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585104260T Expired - Fee Related DE3582608D1 (de) 1984-04-19 1985-04-09 Verfahren und zell-linie zum erhalten von plasminogen-aktivatoren.

Country Status (6)

Country Link
US (1) US4757005A (de)
EP (1) EP0158958B1 (de)
JP (1) JPH03151873A (de)
DE (1) DE3582608D1 (de)
DK (1) DK176385A (de)
NO (1) NO168184C (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889808A (en) * 1985-10-01 1989-12-26 American Home Products Method of enchancing t-PA and SCU-PA production
PT84991B (pt) * 1986-06-06 1990-03-08 Genentech Inc Processo para a producao de actividador do plasminogenio biologicamente activo
JPS6427472A (en) * 1987-07-21 1989-01-30 Meiji Milk Prod Co Ltd Production of human tissue plasminogen activator and cell strain using therein
GB8723082D0 (en) * 1987-10-01 1987-11-04 Porton Prod Ltd Enzyme production
AU4187389A (en) * 1988-08-02 1990-03-05 Invitron Corporation Method for preparing tpa compositions
EP0449950A4 (en) * 1988-12-14 1991-10-16 Us Health Cell culture medium for human liver epithelial cell line
US5292655A (en) * 1990-01-29 1994-03-08 Wille Jr John J Method for the formation of a histologically-complete skin substitute
USH1532H (en) * 1993-11-03 1996-05-07 Genetics Institute, Inc. Adaption of mammalian cell lines to high cell densities
US6051401A (en) * 1998-07-28 2000-04-18 Bayer Corporation Methods and constructs for protein expression
DK2373783T3 (da) * 2008-12-30 2018-01-29 Baxalta GmbH Fremgangsmåde til at forbedre cellevækst under anvendelse af alkyl-amin-n-oxid (aanox)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904480A (en) * 1972-10-24 1975-09-09 Lilly Co Eli Enhanced production of plasminogen activator
US4232124A (en) * 1979-04-23 1980-11-04 Mann George F Method of producing plasminogen activator
US4335215A (en) * 1980-08-27 1982-06-15 Monsanto Company Method of growing anchorage-dependent cells
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
US4537860A (en) * 1982-12-08 1985-08-27 Monsanto Company Static cell culture maintenance system
NZ206699A (en) * 1982-12-30 1989-08-29 Bio Response Inc Process for the production of serum independent cell lines
JPS59196824A (ja) * 1983-04-21 1984-11-08 Kowa Co 吸着防止剤
JPS6041612A (ja) * 1983-08-13 1985-03-05 Mihama Hisaharu 血栓症予防及び治療剤
US4550080A (en) * 1984-06-05 1985-10-29 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a plasminogen activator

Also Published As

Publication number Publication date
NO168184C (no) 1992-01-22
US4757005A (en) 1988-07-12
DK176385A (da) 1985-10-20
NO851452L (no) 1985-10-21
EP0158958A3 (en) 1988-01-07
EP0158958A2 (de) 1985-10-23
DK176385D0 (da) 1985-04-18
EP0158958B1 (de) 1991-04-24
JPH03151873A (ja) 1991-06-28
NO168184B (no) 1991-10-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee