DE3580513D1 - Verfahren zur isolierung von monoklonalen antikoerpern aus hybridomas-kulturen. - Google Patents

Verfahren zur isolierung von monoklonalen antikoerpern aus hybridomas-kulturen.

Info

Publication number
DE3580513D1
DE3580513D1 DE8585870063T DE3580513T DE3580513D1 DE 3580513 D1 DE3580513 D1 DE 3580513D1 DE 8585870063 T DE8585870063 T DE 8585870063T DE 3580513 T DE3580513 T DE 3580513T DE 3580513 D1 DE3580513 D1 DE 3580513D1
Authority
DE
Germany
Prior art keywords
insulating
monoclonal antibody
hybridomas
cultures
hybridomas cultures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585870063T
Other languages
English (en)
Inventor
Lewis, Jr
Jitka Vera Olander
William Robert Tolbert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Application granted granted Critical
Publication of DE3580513D1 publication Critical patent/DE3580513D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE8585870063T 1984-05-08 1985-05-07 Verfahren zur isolierung von monoklonalen antikoerpern aus hybridomas-kulturen. Expired - Fee Related DE3580513D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/608,283 US4533496A (en) 1984-05-08 1984-05-08 Method of isolating monoclonal antibodies from hybridoma cultures

Publications (1)

Publication Number Publication Date
DE3580513D1 true DE3580513D1 (de) 1990-12-20

Family

ID=24435801

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585870063T Expired - Fee Related DE3580513D1 (de) 1984-05-08 1985-05-07 Verfahren zur isolierung von monoklonalen antikoerpern aus hybridomas-kulturen.

Country Status (6)

Country Link
US (1) US4533496A (de)
EP (1) EP0162034B1 (de)
JP (1) JPS60243097A (de)
AU (1) AU579628B2 (de)
CA (1) CA1236409A (de)
DE (1) DE3580513D1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051120A (ja) * 1983-08-31 1985-03-22 Chemo Sero Therapeut Res Inst 単純ヘルペスサブユニットワクチン
US4933435A (en) * 1989-04-05 1990-06-12 Bioprobe International Antibody purification process
US5580774A (en) * 1989-07-31 1996-12-03 Eli Lilly And Company Chimeric antibodies directed against a human glycoprotein antigen
ZA923679B (en) * 1991-06-21 1993-01-27 Pro Soma Sarl Diagnostic method
EP0583980A1 (de) * 1992-08-20 1994-02-23 Eli Lilly And Company Verfahren zur Herstellung von monoklonalen Antikörpern aus Kaninchen
JPH06323712A (ja) 1993-04-20 1994-11-25 E I Du Pont De Nemours & Co 霧化した極低温液滴の閉じ込め帯域を用いて凍結粒子を製造する方法および装置
FR2902799B1 (fr) 2006-06-27 2012-10-26 Millipore Corp Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
US8163886B2 (en) 2006-12-21 2012-04-24 Emd Millipore Corporation Purification of proteins
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
KR101431856B1 (ko) * 2007-01-22 2014-08-27 제넨테크, 인크. 항체의 고분자전해질 침전 및 정제
US20120177610A1 (en) 2007-09-19 2012-07-12 Kieu Hoang Manufacturing and Purification Processes of Complex Protein found in Fraction IV to make a separated Apo, Transferrin , and Alpha 1 Anti strepsin (A1AT) or A combined Transferrin / Apo/Human Albumin/A1AT and all new found proteins
WO2009151514A1 (en) 2008-06-11 2009-12-17 Millipore Corporation Stirred tank bioreactor
ES2749232T3 (es) * 2008-12-16 2020-03-19 Emd Millipore Corp Reactor de tanque agitado y procedimiento
KR101551295B1 (ko) 2010-05-17 2015-09-08 이엠디 밀리포어 코포레이션 생체분자 정제용 자극 반응성 중합체
TW201335181A (zh) * 2012-01-31 2013-09-01 Kieu Hoang ５５種新發現的蛋白質之序列及其應用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3555001A (en) * 1969-05-29 1971-01-12 Monsanto Co Process for the fractionation of plasma and serum using water-insoluble polyelectrolytes containing diloweralkylaminoloweralkylimide groups
NL7708005A (nl) * 1976-07-22 1978-01-24 Monsanto Co Werkwijze voor de bereiding van serumalbumine.
US4382028A (en) * 1982-07-19 1983-05-03 Monsanto Company Separation of plasma proteins from cell culture systems
JPS5929622A (ja) * 1982-08-10 1984-02-16 Meiji Seika Kaisha Ltd モノクロ−ナル抗体、その製造法およびその用途
US4469630A (en) * 1983-11-25 1984-09-04 J. T. Baker Chemical Co. Purification of monoclonal antibodies

Also Published As

Publication number Publication date
EP0162034B1 (de) 1990-11-14
US4533496A (en) 1985-08-06
JPS60243097A (ja) 1985-12-03
AU4203185A (en) 1985-11-14
AU579628B2 (en) 1988-12-01
EP0162034A3 (en) 1987-05-20
EP0162034A2 (de) 1985-11-21
JPH0588116B2 (de) 1993-12-21
CA1236409A (en) 1988-05-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee