DE3576651D1 - Verfahren zur polymerisation von haemoglobin mittels verknuepfender reagenzien. - Google Patents

Verfahren zur polymerisation von haemoglobin mittels verknuepfender reagenzien.

Info

Publication number
DE3576651D1
DE3576651D1 DE8585106057T DE3576651T DE3576651D1 DE 3576651 D1 DE3576651 D1 DE 3576651D1 DE 8585106057 T DE8585106057 T DE 8585106057T DE 3576651 T DE3576651 T DE 3576651T DE 3576651 D1 DE3576651 D1 DE 3576651D1
Authority
DE
Germany
Prior art keywords
haemoglobin
polymerizing
linking reagents
hemoglobin
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585106057T
Other languages
English (en)
Inventor
Wolfgang Prof Dr Dr Barnikol
Oswald Dr Burkhard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SANGUIBIOTECH AG, 58455 WITTEN, DE
Original Assignee
Barnikol Wolfgang
Burkhard Oswald
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39595625&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3576651(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Barnikol Wolfgang, Burkhard Oswald filed Critical Barnikol Wolfgang
Application granted granted Critical
Publication of DE3576651D1 publication Critical patent/DE3576651D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/207497—Molecular oxygen
DE8585106057T 1983-06-09 1985-05-17 Verfahren zur polymerisation von haemoglobin mittels verknuepfender reagenzien. Expired - Fee Related DE3576651D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833320752 DE3320752A1 (de) 1983-06-09 1983-06-09 Lumineszierende schichten zur verwendung in vorrichtungen zur bestimmung der sauerstoffkonzentration in gasen und dergleichen durch messung der lumineszensverringerung
EP85106057A EP0201618B1 (de) 1983-06-09 1985-05-17 Verfahren zur Polymerisation von Hämoglobin mittels verknüpfender Reagenzien

Publications (1)

Publication Number Publication Date
DE3576651D1 true DE3576651D1 (de) 1990-04-26

Family

ID=39595625

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19833320752 Withdrawn DE3320752A1 (de) 1983-06-06 1983-06-09 Lumineszierende schichten zur verwendung in vorrichtungen zur bestimmung der sauerstoffkonzentration in gasen und dergleichen durch messung der lumineszensverringerung
DE8585106057T Expired - Fee Related DE3576651D1 (de) 1983-06-09 1985-05-17 Verfahren zur polymerisation von haemoglobin mittels verknuepfender reagenzien.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19833320752 Withdrawn DE3320752A1 (de) 1983-06-06 1983-06-09 Lumineszierende schichten zur verwendung in vorrichtungen zur bestimmung der sauerstoffkonzentration in gasen und dergleichen durch messung der lumineszensverringerung

Country Status (5)

Country Link
US (1) US4775514A (de)
EP (2) EP0128497B1 (de)
JP (1) JPS608736A (de)
AT (1) ATE51153T1 (de)
DE (2) DE3320752A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7598220B2 (en) 2003-11-12 2009-10-06 Sanguibio Tech Gmbh Use of hyperpolymeric hemoglobin for the treatment of pulmonary edema
WO2013013799A1 (en) 2011-07-23 2013-01-31 Sastomed Gmbh Wound spray
WO2013104698A1 (en) 2012-01-13 2013-07-18 Sastomed Gmbh Scarring reducing wound treatment

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2600149B2 (ja) * 1986-10-28 1997-04-16 株式会社島津製作所 分光分析方法
US5462052A (en) * 1987-01-30 1995-10-31 Minnesota Mining And Manufacturing Co. Apparatus and method for use in measuring a compositional parameter of blood
DE3714351A1 (de) * 1987-04-29 1988-11-17 Barnikol Wolfgang Verfahren zur modifikation, insbesondere zur polymerisation von haemoglobin in vitro
US5043285A (en) * 1987-07-09 1991-08-27 Allied-Signal Inc. Optical detection of oxygen
DK163194C (da) * 1988-12-22 1992-06-22 Radiometer As Fremgangsmaade ved fotometrisk in vitro bestemmelse af en blodgasparameter i en blodproeve
US5564419A (en) * 1987-11-25 1996-10-15 Radiometer A/S Method of photometric in vitro determination of the content of oxygen in a blood sample
US4994396A (en) * 1987-12-14 1991-02-19 The Dow Chemical Company Method for measuring the concentration or partial pressure of oxygen
US5173432A (en) * 1987-12-14 1992-12-22 The Dow Chemical Company Apparatus and method for measuring the concentration or partial pressure of oxygen
DE3841105C2 (de) * 1988-12-07 1994-09-01 Wolfgang Karl Richard Barnikol Verfahren zur Aufreinigung und Modifikation von polymerisiertem Hämoglobin
US5015715A (en) * 1989-08-16 1991-05-14 Puritan-Bennett Corporation Method for bonding an analyte-sensitive dye compound to an addition-cure silicone
US5102625A (en) * 1990-02-16 1992-04-07 Boc Health Care, Inc. Apparatus for monitoring a chemical concentration
US5175016A (en) * 1990-03-20 1992-12-29 Minnesota Mining And Manufacturing Company Method for making gas sensing element
US5081042A (en) * 1990-03-20 1992-01-14 Minnesota Mining And Manufacturing Company Ionic component sensor and method for making and using same
AT394906B (de) * 1990-03-27 1992-07-27 Avl Verbrennungskraft Messtech Verfahren zur qualitaetskontrolle von verpackten, organischen stoffen, sowie ein verpackungsmaterial zur durchfuehrung des verfahrens
US5081041A (en) * 1990-04-03 1992-01-14 Minnesota Mining And Manufacturing Company Ionic component sensor and method for making and using same
AT398003B (de) * 1991-05-10 1994-08-25 Avl Verbrennungskraft Messtech Vorrichtung zur bestimmung des materieflusses
US5296381A (en) * 1991-08-08 1994-03-22 Minnesota Mining & Manufacturing Co. Sensing elements and methods for making and using same
US5409666A (en) * 1991-08-08 1995-04-25 Minnesota Mining And Manufacturing Company Sensors and methods for sensing
AT399402B (de) * 1992-07-09 1995-05-26 Avl Verbrennungskraft Messtech Sensormembran eines optischen sensors zur bestimmung eines physikalischen oder chemischen parameters einer probe
AT400907B (de) * 1992-07-24 1996-04-25 Avl Verbrennungskraft Messtech Sensormembran eines optischen sensors
DE4418973A1 (de) * 1994-05-31 1995-12-14 Barnikol Wolfgang Verfahren zur Herstellung molekular-einheitlicher hyperpolymerer Hämoglobine
US6815211B1 (en) 1998-08-04 2004-11-09 Ntc Technology Oxygen monitoring methods and apparatus (I)
US6325978B1 (en) 1998-08-04 2001-12-04 Ntc Technology Inc. Oxygen monitoring and apparatus
US7335164B2 (en) 1996-07-15 2008-02-26 Ntc Technology, Inc. Multiple function airway adapter
US5919710A (en) * 1996-07-18 1999-07-06 The United States Of America As Represented By The Secretary Of The Air Force Optical method for quantitating dissolved oxygen in fuel
EP0854151A1 (de) 1997-01-20 1998-07-22 SanguiBioTech AG Verfahren zur Gewinnung einheitlicher Fraktionen hyperpolymerer Hämoglobine
AT409306B (de) 1997-10-03 2002-07-25 Hoffmann La Roche Optisch chemischer sensor
DE10031744A1 (de) 2000-06-29 2002-01-17 Sanguibio Tech Ag Mit Blutplasma verträgliche, vernetzte und mit Polyalkylenoxiden konjugierte Säugetierhämoglobine als künstliche medizinische Sauerstoffträger, ihre Herstellung und ihre Verwendung
US6632402B2 (en) * 2001-01-24 2003-10-14 Ntc Technology Inc. Oxygen monitoring apparatus
US20070243618A1 (en) * 2006-04-11 2007-10-18 Oxysense, Inc. Device and method for non-invasive oxygen sensing of sealed packages
US20090128344A1 (en) * 2007-11-21 2009-05-21 General Electric Company Systems, Apparatuses And Methods For Monitoring Physical Conditions Of A Bed Occupant
US8581212B2 (en) * 2009-01-23 2013-11-12 Chimei Innolux Corporation Portable UV monitoring device
CN114414536A (zh) * 2021-10-15 2022-04-29 上海蓝长自动化科技有限公司 一种基于荧光的溶解氧敏感膜制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3925344A (en) * 1973-04-11 1975-12-09 Community Blood Council Plasma protein substitute
DE2449885C3 (de) * 1974-10-21 1980-04-30 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung von chemisch modifizierten haltbaren Hämoglobinpräparaten sowie das nach diesem Verfahren hergestellte modifizierte Hämoglobinpräparat
US4001200A (en) * 1975-02-27 1977-01-04 Alza Corporation Novel polymerized, cross-linked, stromal-free hemoglobin
US4001401A (en) * 1975-02-02 1977-01-04 Alza Corporation Blood substitute and blood plasma expander comprising polyhemoglobin
DE2508637C3 (de) * 1975-02-28 1979-11-22 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Anordnung zur optischen Messung von Blutgasen
CA1055932A (en) * 1975-10-22 1979-06-05 Hematech Inc. Blood substitute based on hemoglobin
DE2714252C2 (de) * 1977-03-31 1983-08-18 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung eines für die intravenöse Injektion geeigneten Hämoglobinpräparates mit erhöhter Sauerstoffabgabe gegenüber Erythrozyten
DE2823318C2 (de) * 1978-05-29 1980-07-31 Draegerwerk Ag, 2400 Luebeck Vorrichtung zur Messung des Sauerstoffgehalts eines fließenden Probemediums
US4399099A (en) * 1979-09-20 1983-08-16 Buckles Richard G Optical fiber apparatus for quantitative analysis
US4390521A (en) * 1980-04-11 1983-06-28 Exxon Research And Engineering Co. Artificial red cells
US4376059A (en) * 1980-04-11 1983-03-08 Exxon Research And Engineering Co. Process for preparing artificial red cells
US4577109A (en) * 1980-10-06 1986-03-18 Regents Of The University Of California Remote multi-position information gathering system and method
GB2103786A (en) * 1981-08-14 1983-02-23 Ici Plc Fibre optic sensor
DE3144705C2 (de) * 1981-11-11 1983-12-08 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung eines lagerstabilen, vernetzten Hämoglobinpräparates mit hoher Sauerstoff-Transportkapazität, sowie das nach diesem Verfahren hergestellte Hämoglobinpräparat
DE3148830A1 (de) * 1981-12-10 1983-06-23 Wolfgang Prof. Dr.Dr. 6500 Mainz Barnikol "vorrichtung zur bestimmung der sauerstoffkonzentration in gasen, fluessigkeiten und geweben"
SE454115B (sv) * 1982-09-13 1988-03-28 Wallac Oy Homogenfasanalys med lantanidkelat som merksubstans
US4557900A (en) * 1982-09-28 1985-12-10 Cardiovascular Devices, Inc. Optical sensor with beads
AT379688B (de) * 1982-11-22 1986-02-10 List Hans Sensorelement zur bestimmung des o2-gehaltes einer probe
AT377095B (de) * 1982-11-23 1985-02-11 List Hans Sensorelement zur bestimmung des o2-gehaltes einer probe sowie verfahren zur herstellung desselben
US4558014A (en) * 1983-06-13 1985-12-10 Myron J. Block Assay apparatus and methods

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7598220B2 (en) 2003-11-12 2009-10-06 Sanguibio Tech Gmbh Use of hyperpolymeric hemoglobin for the treatment of pulmonary edema
WO2013013799A1 (en) 2011-07-23 2013-01-31 Sastomed Gmbh Wound spray
US10471175B2 (en) 2011-07-23 2019-11-12 Mölnlycke Health Care Ab Wound spray
US10646613B2 (en) 2011-07-23 2020-05-12 Mölnlycke Health Care Ab Wound spray
WO2013104698A1 (en) 2012-01-13 2013-07-18 Sastomed Gmbh Scarring reducing wound treatment

Also Published As

Publication number Publication date
EP0128497A3 (en) 1986-07-02
ATE51153T1 (de) 1990-04-15
EP0201618A1 (de) 1986-11-20
EP0201618B1 (de) 1990-03-21
EP0128497A2 (de) 1984-12-19
JPS608736A (ja) 1985-01-17
EP0128497B1 (de) 1989-03-15
DE3320752A1 (de) 1984-12-13
US4775514A (en) 1988-10-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANGUIBIOTECH AG, 58455 WITTEN, DE

8381 Inventor (new situation)

Free format text: BARNIKOL, WOLFGANG, PROF.DR.DR., 55128 MAINZ, DE BURKHARD, OSWALD, DR., 67819 KRIEGSFELD, DE

8339 Ceased/non-payment of the annual fee