DE3575872D1 - Thioether-sorbentmittel fuer die trennung von proteinen und dergleichen. - Google Patents

Thioether-sorbentmittel fuer die trennung von proteinen und dergleichen.

Info

Publication number
DE3575872D1
DE3575872D1 DE8585850148T DE3575872T DE3575872D1 DE 3575872 D1 DE3575872 D1 DE 3575872D1 DE 8585850148 T DE8585850148 T DE 8585850148T DE 3575872 T DE3575872 T DE 3575872T DE 3575872 D1 DE3575872 D1 DE 3575872D1
Authority
DE
Germany
Prior art keywords
sorbent
thioether
proteins
separation
thioether sorbent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585850148T
Other languages
German (de)
English (en)
Inventor
Jerker Porath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE3575872D1 publication Critical patent/DE3575872D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE8585850148T 1984-05-17 1985-04-29 Thioether-sorbentmittel fuer die trennung von proteinen und dergleichen. Expired - Lifetime DE3575872D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8402662A SE470261B (sv) 1984-05-17 1984-05-17 Adsorbent för separation och immobilisering av proteiner, sätt att framställa ett adsorbent, samt dess användning för biopolymer fraktionering

Publications (1)

Publication Number Publication Date
DE3575872D1 true DE3575872D1 (de) 1990-03-15

Family

ID=20355913

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585850148T Expired - Lifetime DE3575872D1 (de) 1984-05-17 1985-04-29 Thioether-sorbentmittel fuer die trennung von proteinen und dergleichen.

Country Status (4)

Country Link
EP (1) EP0165912B1 (enExample)
JP (1) JPS615099A (enExample)
DE (1) DE3575872D1 (enExample)
SE (1) SE470261B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE462165B (sv) * 1988-02-26 1990-05-14 Porath Jerker Saett att paa en baerare adsorbera sammansatta proteinkomplex, saerskilt vid biospecifika bestaemningsmetoder
US5071819A (en) * 1988-08-26 1991-12-10 Ibc Advanced Technologies Sulfur and nitrogen-containing hydrocarbons and process of using same in recovering and concentrating desired ions from solutions thereof
US5149425A (en) * 1988-11-09 1992-09-22 Chembiomed, Ltd. Affinity supports for hemoperfusion
US5240601A (en) * 1988-11-09 1993-08-31 Chembiomed, Ltd. Affinity supports for hemoperfusion
WO1990009832A1 (en) * 1989-02-21 1990-09-07 Eastman Kodak Company High performance affinity chromatography column comprising non-porous, monodisperse polymeric packing material
JPH0750086B2 (ja) * 1989-09-13 1995-05-31 ダイソー株式会社 クロマトグラフ充填剤及びこれによる水溶性有機化合物の分離法
DK52791D0 (da) * 1991-03-22 1991-03-22 Kem En Tec As Adsorptionsmatricer
ATE154526T1 (de) * 1992-04-16 1997-07-15 Merck Patent Gmbh Aktivierte trägermaterialien, ihre herstellung und verwendung
US5502022A (en) * 1994-05-16 1996-03-26 Biosepra, Inc. Chromatography adsorbents utilizing mercapto heterocyclic ligands
US5789578A (en) * 1996-01-11 1998-08-04 Massey University Methods for the preparation of resins with ligands attached thereto through a linking group comprising sulfide, sulfoxide or sulfone functionality
DE19623131C2 (de) * 1996-06-10 2001-10-31 Gerhard Harry Scholz Konjugat, Verfahren zu dessen Herstellung sowie dessen Verwendung zur Bindung von Substanzen
EP1386660B1 (en) 1996-08-30 2009-09-02 Upfront Chromatography A/S Isolation of immunoglobulins
SE9700769D0 (sv) 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna
GB0219681D0 (en) * 2002-08-23 2002-10-02 Anglo Platinum Ltd Chromatographic medium
CA2500903A1 (en) 2002-09-13 2004-03-25 Pall Corporation Preparation and use of mixed mode solid substrates for chromatography adsorbents and biochip arrays
DE10313324A1 (de) * 2003-03-25 2004-10-21 Instraction Gmbh Verfahren zur selektiven Bindung eines Substrats an Sorbentien durch mindestens bivalente Bindung
US8021889B2 (en) 2004-01-20 2011-09-20 Pall Corporation Chromatographic material for the absorption of proteins at physiological ionic strength
EP1754534A1 (de) 2005-08-03 2007-02-21 MERCK PATENT GmbH Hydrophiles vernetztes Polymer
US20180126298A1 (en) 2015-05-22 2018-05-10 Merck Patent Gmbh Device for substance separation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2319495C2 (de) * 1973-04-17 1985-01-10 Yeda Research And Development Co., Ltd., Rehovot Verfahren zum selektiven, reversiblen Binden von Biomolekülen an ein Adsorbens in einer chromatographischen Säule
LU73094A1 (enExample) * 1975-07-29 1977-03-24
US4111838A (en) * 1977-09-09 1978-09-05 Eastman Kodak Company Composition for chromatography
GB2092470B (en) * 1981-02-10 1984-07-18 Tanabe Seiyaku Co Method for reducing the pyrogen content of or removing pyrogens from solutions contaminated therewith

Also Published As

Publication number Publication date
SE8402662D0 (sv) 1984-05-17
JPH059440B2 (enExample) 1993-02-04
EP0165912A2 (en) 1985-12-27
EP0165912A3 (en) 1987-01-28
JPS615099A (ja) 1986-01-10
SE470261B (sv) 1993-12-20
EP0165912B1 (en) 1990-02-07
SE8402662L (sv) 1985-11-18

Similar Documents

Publication Publication Date Title
DE3572602D1 (en) Sulfone activated thioether adsorbents for the separation of proteins and the like
DE3583359D1 (de) Trennung von partikeln.
DE3687043D1 (de) Ausgabe von blattfoermigem material.
DK552285A (da) Proteinkonjugat
DE3673222D1 (de) Trennungsmittel und trennverfahren fuer metalle.
DE68909037D1 (de) Belüftung von Flüssigkeiten.
DE3485723D1 (de) Verfahren und signalsequenz fuer die extrazellulare herstellung von proteinmaterial.
FI872712A0 (fi) Utskaenkningsanordning foer rullat material med matrulle foersedd med glidskaerare.
DE3675024D1 (de) Fahrzeugaufhaengungsvorrichtungen.
EP0165912A3 (en) Thioether adsorbent intended for the separation of proteins and the like
DE3671533D1 (de) Immunotestverfahren und reagenz dafuer.
DE3788807D1 (de) Fusionsproteine und -partikel.
DE3585657D1 (de) Gegenseitige trennung von proteinen.
FI860573A7 (fi) Transport- och distributionssystem foer material.
AT384176B (de) Druckwechseladsorber fuer die aufnahme von koernigen adsorptionsmitteln
FI872648A7 (fi) Limiliimaliitos.
DE3481556D1 (de) System zur unterscheidung und zur lagebestimmung von objekten.
DE3576527D1 (de) Trennung von aminosaeureracematen.
ATA152985A (de) Werkstoff zur herstellung von stanz- und gegenplatten
FI863693L (fi) Ur sulfatsvartlut haerledd fuktande komposition.
ES290558Y (es) Disposicion para la separacion de liquidos
ES288974Y (es) Sujetador de cordones y similares
FI862902L (fi) Absorberande material foer nukleaer straolning.
FI873606A7 (fi) Ihmisen glykoalbumiinin määrittämiseen käyttökelpoisia vasta-aineita.
FI870257A7 (fi) Bearbetningsfoerfarande foer material.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee