DE3575420D1 - 6-sauerstoffhaltige-1,3,4,5-tetrahydrobenz(cd)indole-4-amine. - Google Patents
6-sauerstoffhaltige-1,3,4,5-tetrahydrobenz(cd)indole-4-amine.Info
- Publication number
- DE3575420D1 DE3575420D1 DE8585303556T DE3575420T DE3575420D1 DE 3575420 D1 DE3575420 D1 DE 3575420D1 DE 8585303556 T DE8585303556 T DE 8585303556T DE 3575420 T DE3575420 T DE 3575420T DE 3575420 D1 DE3575420 D1 DE 3575420D1
- Authority
- DE
- Germany
- Prior art keywords
- tetrahydrobenz
- indole
- amine
- oxygen
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61383984A | 1984-05-24 | 1984-05-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3575420D1 true DE3575420D1 (de) | 1990-02-22 |
Family
ID=24458880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585303556T Expired - Fee Related DE3575420D1 (de) | 1984-05-24 | 1985-05-21 | 6-sauerstoffhaltige-1,3,4,5-tetrahydrobenz(cd)indole-4-amine. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0162695B1 (de) |
JP (1) | JPS60258162A (de) |
AT (1) | ATE49592T1 (de) |
AU (1) | AU581000B2 (de) |
CA (1) | CA1266482A1 (de) |
DE (1) | DE3575420D1 (de) |
DK (1) | DK222385A (de) |
ES (2) | ES8700233A1 (de) |
GR (1) | GR851263B (de) |
PT (1) | PT80524B (de) |
ZA (1) | ZA853913B (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3346573A1 (de) * | 1983-12-23 | 1985-07-04 | Troponwerke GmbH & Co KG, 5000 Köln | 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung |
US4983622A (en) * | 1984-02-06 | 1991-01-08 | Eli Lilly And Company | 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles |
IL74222A (en) * | 1984-02-06 | 1988-07-31 | Lilly Co Eli | 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them |
US5026869A (en) * | 1984-02-06 | 1991-06-25 | Eli Lilly And Company | 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles |
DE3718892A1 (de) * | 1987-06-05 | 1988-12-22 | Bayer Ag | Polyhydrobenz(c,d)indol-sulfonamide |
DE3809155A1 (de) * | 1988-03-18 | 1989-09-28 | Bayer Ag | 1,3,4,5-tetrahydrobenz-(c,d)-indole |
US5204340A (en) * | 1989-04-11 | 1993-04-20 | Eli Lilly And Company | Tetrahydrobenz(c,d)indole serotonin agonists |
US5302612A (en) * | 1990-02-26 | 1994-04-12 | Eli Lilly And Company | 6-substituted-hexahydrobenz[cd]indoles |
US5229409A (en) * | 1990-08-15 | 1993-07-20 | Eli Lilly And Company | 6-substituted-tetrahydrobenz[cd]indoles |
US5229410A (en) * | 1990-08-15 | 1993-07-20 | Eli Lilly And Company | 6-substituted-hexahydrobenz[cd]indoles |
US5347013A (en) * | 1991-03-28 | 1994-09-13 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles |
US5364856A (en) * | 1991-03-28 | 1994-11-15 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles |
US5244911A (en) * | 1991-03-28 | 1993-09-14 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof |
US5643934A (en) * | 1991-03-28 | 1997-07-01 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz [CD]indoles |
US5244912A (en) * | 1991-03-28 | 1993-09-14 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof |
IL109872A (en) * | 1993-06-10 | 2000-12-06 | Lilly Co Eli | Tetrahydrobenz ¬CD¾ indole-6-carboxamides for use in preventing emesis and pharmaceutical compositions comprising same |
FR2732964B1 (fr) * | 1995-04-14 | 1997-05-16 | Adir | Nouveaux amides tricycliques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3194811A (en) * | 1963-09-05 | 1965-07-13 | Merck & Co Inc | Aroyl-benzindolyl acids |
CH517732A (de) * | 1969-10-24 | 1972-01-15 | Sandoz Ag | Verfahren zur Herstellung neuer Guanidin- Verbindungen |
US4110339A (en) * | 1977-11-25 | 1978-08-29 | Eli Lilly And Company | 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole |
US4282240A (en) * | 1979-11-23 | 1981-08-04 | Merck & Co., Inc. | Amino substituted tetrahydrobenzindoles |
DE3346573A1 (de) * | 1983-12-23 | 1985-07-04 | Troponwerke GmbH & Co KG, 5000 Köln | 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung |
IL74222A (en) * | 1984-02-06 | 1988-07-31 | Lilly Co Eli | 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them |
-
1985
- 1985-04-09 CA CA000478535A patent/CA1266482A1/en active Granted
- 1985-05-20 DK DK222385A patent/DK222385A/da not_active Application Discontinuation
- 1985-05-21 DE DE8585303556T patent/DE3575420D1/de not_active Expired - Fee Related
- 1985-05-21 EP EP85303556A patent/EP0162695B1/de not_active Expired - Lifetime
- 1985-05-21 AT AT85303556T patent/ATE49592T1/de active
- 1985-05-22 GR GR851263A patent/GR851263B/el unknown
- 1985-05-23 AU AU42796/85A patent/AU581000B2/en not_active Ceased
- 1985-05-23 ZA ZA853913A patent/ZA853913B/xx unknown
- 1985-05-23 JP JP60111986A patent/JPS60258162A/ja active Pending
- 1985-05-23 ES ES543421A patent/ES8700233A1/es not_active Expired
- 1985-05-23 PT PT80524A patent/PT80524B/pt not_active IP Right Cessation
-
1986
- 1986-02-13 ES ES551944A patent/ES8706117A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES8706117A1 (es) | 1987-06-01 |
GR851263B (de) | 1985-11-25 |
EP0162695B1 (de) | 1990-01-17 |
CA1266675C (de) | 1990-03-13 |
DK222385A (da) | 1985-11-25 |
DK222385D0 (da) | 1985-05-20 |
JPS60258162A (ja) | 1985-12-20 |
ATE49592T1 (de) | 1990-02-15 |
PT80524A (en) | 1985-06-01 |
ES551944A0 (es) | 1987-06-01 |
AU581000B2 (en) | 1989-02-09 |
AU4279685A (en) | 1985-11-28 |
PT80524B (en) | 1987-04-06 |
ES543421A0 (es) | 1986-09-16 |
ES8700233A1 (es) | 1986-09-16 |
ZA853913B (en) | 1986-01-29 |
CA1266482A1 (en) | 1990-03-06 |
EP0162695A1 (de) | 1985-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |