DE3575132D1 - 2-phenylalkyl-3-aminoalkyl-4(3h)-chinazolinonen, verfahren zu deren herstellung, pharmazeutische zusammenstellungen und verwendung. - Google Patents

2-phenylalkyl-3-aminoalkyl-4(3h)-chinazolinonen, verfahren zu deren herstellung, pharmazeutische zusammenstellungen und verwendung.

Info

Publication number
DE3575132D1
DE3575132D1 DE8585109193T DE3575132T DE3575132D1 DE 3575132 D1 DE3575132 D1 DE 3575132D1 DE 8585109193 T DE8585109193 T DE 8585109193T DE 3575132 T DE3575132 T DE 3575132T DE 3575132 D1 DE3575132 D1 DE 3575132D1
Authority
DE
Germany
Prior art keywords
group
carbon atoms
sub
sup
integer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585109193T
Other languages
English (en)
Inventor
Tetsuo Research Lab Mit Sekiya
Mikio Research Lab Mit Tsutsui
Daijiro Research Lab Mit Horii
Akira Research Lab M Ishibashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Application granted granted Critical
Publication of DE3575132D1 publication Critical patent/DE3575132D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8585109193T 1984-07-26 1985-07-23 2-phenylalkyl-3-aminoalkyl-4(3h)-chinazolinonen, verfahren zu deren herstellung, pharmazeutische zusammenstellungen und verwendung. Expired - Fee Related DE3575132D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15408684A JPS6136273A (ja) 1984-07-26 1984-07-26 ２−フエニルアルキル−４（３ｈ）−キナゾリノン誘導体

Publications (1)

Publication Number Publication Date
DE3575132D1 true DE3575132D1 (de) 1990-02-08

Family

ID=15576584

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585109193T Expired - Fee Related DE3575132D1 (de) 1984-07-26 1985-07-23 2-phenylalkyl-3-aminoalkyl-4(3h)-chinazolinonen, verfahren zu deren herstellung, pharmazeutische zusammenstellungen und verwendung.

Country Status (9)

Country Link
US (1) US4668682A (de)
EP (1) EP0169537B1 (de)
JP (1) JPS6136273A (de)
KR (1) KR860001078A (de)
AT (1) ATE49199T1 (de)
CA (1) CA1266266A (de)
DE (1) DE3575132D1 (de)
DK (1) DK339685A (de)
HU (1) HU194836B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2037630C (en) * 1990-03-07 2001-07-03 Akira Morimoto Nitrogen-containing heterocylic compounds, their production and use
GB9116207D0 (en) * 1991-07-26 1991-09-11 Ici Plc Novel compounds
US5430148A (en) * 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
IT1266992B1 (it) * 1993-04-16 1997-01-24 Alfa Wassermann Spa Composti eterociclici, a struttura correlabile alle banzammidi, attivi nelle patologie gastro-intestinali, ad attivita' procinetica ed
US5756502A (en) * 1994-08-08 1998-05-26 Warner-Lambert Company Quinazolinone derivatives as cholyecystokinin (CCK) ligands
EP0855387A4 (de) * 1995-09-07 1999-09-15 Kissei Pharmaceutical 2-acetylaminobenzamid derivate zur prävention und heilung von krankheiten die durch supermultiplikation von vaskulären intimalzellen verursacht werden
DE69842109D1 (de) * 1997-08-21 2011-03-10 Shiseido Co Ltd Chinazolin-4-on Derivate, deren Herstellung und deren Verwendung als Haarwuchsmittel oder in äusserlich anzuwendenden Hautpflegemitteln
US6444816B1 (en) 1997-10-27 2002-09-03 Dr. Reddy's Research Foundation Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof
US6337332B1 (en) * 1998-09-17 2002-01-08 Pfizer Inc. Neuropeptide Y receptor antagonists
AU7654800A (en) * 1999-09-28 2001-04-30 Merck Patent Gmbh Quinazolinones
US6890930B1 (en) 1999-09-28 2005-05-10 3-Dimensional Pharmaceuticals, Inc. Quinazolinones
EP1322625A2 (de) * 2000-10-02 2003-07-02 Molecular Probes Inc. Reagens für markierung biomoleküle mit aldehyde oder keton teile
EP1389103A4 (de) * 2001-04-23 2005-09-14 Univ Virginia Synthese und bewertung neuer phthalimid-kopien als antiangiogene mittel
WO2003043961A2 (en) * 2001-11-19 2003-05-30 Iconix Pharmaceuticals, Inc. Modulators of rho c activity
MXPA05006124A (es) * 2002-12-13 2005-08-16 Hoffmann La Roche Derivados de 3-quinazolin-4-ona.
KR100610731B1 (ko) * 2004-02-24 2006-08-09 한국과학기술연구원 Ｔ-형 칼슘 채널 차단제로서 유용한 ３,４-디히드로퀴나졸린유도체 및 그의 제조 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2020234A1 (de) * 1970-04-25 1971-11-18 Cassella Farbwerke Mainkur Ag Basisch substituierte Derivate des 4(3H)-Chinazolinons

Also Published As

Publication number Publication date
HUT39166A (en) 1986-08-28
DK339685D0 (da) 1985-07-25
EP0169537B1 (de) 1990-01-03
EP0169537A3 (en) 1987-03-25
ATE49199T1 (de) 1990-01-15
EP0169537A2 (de) 1986-01-29
KR860001078A (ko) 1986-02-22
JPS6136273A (ja) 1986-02-20
US4668682A (en) 1987-05-26
HU194836B (en) 1988-03-28
DK339685A (da) 1986-01-27
CA1266266A (en) 1990-02-27

Similar Documents

Publication Publication Date Title
DE3575132D1 (de) 2-phenylalkyl-3-aminoalkyl-4(3h)-chinazolinonen, verfahren zu deren herstellung, pharmazeutische zusammenstellungen und verwendung.
ES8402273A1 (es) Un procedimiento para la preparacion de 1,4-dihidropiridinas.
DK57281A (da) Fremgangsmaade til fremstilling af substituerede imidazolderivater eller syreadditionssalte deraf
ES8307760A1 (es) Un procedimiento para la preparacion de derivados de 4-anilino-pirimidina.
ES534505A0 (es) Un procedimiento para la preparacion de compuestos de 1, 4-dihidropiridina
ATE66674T1 (de) Dihydropyridin-derivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zusammensetzungen, und verfahren zur herstellung dieser zusammensetzungen.
ES8704153A1 (es) Un procedimiento para preparar derivados de pirimidina
MY102921A (en) Amino-alcohol derivatives and processes for their preparation.
IL75165A (en) Dihydropyridines and pharmaceutical compositions containing them
DE69007356D1 (de) Zyklisches Tetrapeptid und Verfahren zu dessen Herstellung.
ATE27455T1 (de) Heterocyclische guanidino-phenylamidine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung.
PH25352A (en) Tetraoxo compounds, pharmaceutical compostions
FI851456L (fi) Foerfarande foer framstaellning av 1-cyklohexyl-3,4-dihydroisokinolinderivat.
ES8600203A1 (es) Procedimiento de preparacion de nuevos derivados aminoetoxibencilalcoholicos y de sus sales de adicion acidas y amonicas cuaternarias
ES479005A1 (es) Un procedimiento para obtener derivados de quinazolina.
ES485333A1 (es) Procedimiento para preparar derivados 5,6,7,8-tetrahidro-4 (3h)-quinazolinonicos y sus sales
EP0218195A3 (de) Bis-(Dibenzo[b,d]pyranyloxy)-propane

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee