DE3571647D1 - A positive retroregulatory element, plasmid and cells comprising said element and their production, a method of enhancing gene expression using said element and a method of enhancing rna half life using said element - Google Patents
A positive retroregulatory element, plasmid and cells comprising said element and their production, a method of enhancing gene expression using said element and a method of enhancing rna half life using said elementInfo
- Publication number
- DE3571647D1 DE3571647D1 DE8585306183T DE3571647T DE3571647D1 DE 3571647 D1 DE3571647 D1 DE 3571647D1 DE 8585306183 T DE8585306183 T DE 8585306183T DE 3571647 T DE3571647 T DE 3571647T DE 3571647 D1 DE3571647 D1 DE 3571647D1
- Authority
- DE
- Germany
- Prior art keywords
- enhancing
- plasmid
- cells
- production
- gene expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/646,709 US4666848A (en) | 1984-08-31 | 1984-08-31 | Polypeptide expression using a portable temperature sensitive control cassette with a positive retroregulatory element |
US06/646,584 US4792523A (en) | 1984-08-31 | 1984-08-31 | 3'Expression enhancing fragments and method |
US06/717,331 US4910141A (en) | 1984-08-31 | 1985-03-29 | 3'-expression enhancing fragments and method |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3571647D1 true DE3571647D1 (en) | 1989-08-24 |
Family
ID=27417773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585306183T Expired DE3571647D1 (en) | 1984-08-31 | 1985-08-30 | A positive retroregulatory element, plasmid and cells comprising said element and their production, a method of enhancing gene expression using said element and a method of enhancing rna half life using said element |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0174785B1 (de) |
JP (1) | JP2558249B2 (de) |
CA (1) | CA1275954C (de) |
DE (1) | DE3571647D1 (de) |
DK (1) | DK397485A (de) |
FI (1) | FI853346L (de) |
NO (1) | NO853313L (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4798791A (en) * | 1984-11-16 | 1989-01-17 | Genex Corporation | Vector for high level gene expression |
US5017477A (en) * | 1985-10-25 | 1991-05-21 | Biotechnica International, Inc. | Enhancing DNA sequencies derived from the sacQ gene |
US4992367A (en) * | 1986-05-12 | 1991-02-12 | Hoffmann-La Roche Inc. | Enhanced expression of human interleukin-2 in mammalian cells |
EP3345918A1 (de) * | 2017-01-05 | 2018-07-11 | Institut National De La Recherche Agronomique | Verwendung des cpcr-regulatorgens für die erhöhung von neuen rekombinanten stämmen von bacillus-thuringiensis mit reduzierter sporulierungskapazität |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4448885A (en) | 1981-04-27 | 1984-05-15 | Board Of The Regents Of The University Of Washington | Bacillus thuringiensis crystal protein in Escherichia coli |
JPS6017441B2 (ja) | 1981-07-10 | 1985-05-02 | ダイセル化学工業株式会社 | 新規なセルロ−スアセテ−トの製造方法 |
FI82266C (fi) | 1982-10-19 | 1991-02-11 | Cetus Corp | Foerfarande foer framstaellning av il-2 -mutein. |
US4713339A (en) * | 1983-01-19 | 1987-12-15 | Genentech, Inc. | Polycistronic expression vector construction |
-
1985
- 1985-08-09 CA CA000488396A patent/CA1275954C/en not_active Expired - Fee Related
- 1985-08-22 NO NO853313A patent/NO853313L/no unknown
- 1985-08-30 DE DE8585306183T patent/DE3571647D1/de not_active Expired
- 1985-08-30 EP EP85306183A patent/EP0174785B1/de not_active Expired
- 1985-08-30 FI FI853346A patent/FI853346L/fi not_active Application Discontinuation
- 1985-08-30 DK DK397485A patent/DK397485A/da not_active Application Discontinuation
- 1985-08-31 JP JP60190976A patent/JP2558249B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FI853346L (fi) | 1986-03-01 |
EP0174785A1 (de) | 1986-03-19 |
CA1275954C (en) | 1990-11-06 |
JPS6170990A (ja) | 1986-04-11 |
NO853313L (no) | 1986-03-03 |
DK397485A (da) | 1986-03-01 |
DK397485D0 (da) | 1985-08-30 |
EP0174785B1 (de) | 1989-07-19 |
JP2558249B2 (ja) | 1996-11-27 |
FI853346A0 (fi) | 1985-08-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: CHIRON CORP. (N.D.GES.D. STAATES DELAWARE), EMERYV |
|
8339 | Ceased/non-payment of the annual fee |