DE3485403D1 - Asymmetrische synthese von alpha-substituierten alpha-cyanomethylalkoholen. - Google Patents

Asymmetrische synthese von alpha-substituierten alpha-cyanomethylalkoholen.

Info

Publication number
DE3485403D1
DE3485403D1 DE8484304951T DE3485403T DE3485403D1 DE 3485403 D1 DE3485403 D1 DE 3485403D1 DE 8484304951 T DE8484304951 T DE 8484304951T DE 3485403 T DE3485403 T DE 3485403T DE 3485403 D1 DE3485403 D1 DE 3485403D1
Authority
DE
Germany
Prior art keywords
alpha
cyanomethyl
alcohols
asymmetric synthesis
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8484304951T
Other languages
English (en)
Inventor
William Roy Jackson
Colin Wilshire
Barry Ross Matthews
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orica Ltd
Original Assignee
ICI Australia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ICI Australia Ltd filed Critical ICI Australia Ltd
Application granted granted Critical
Publication of DE3485403D1 publication Critical patent/DE3485403D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE8484304951T 1983-07-22 1984-07-19 Asymmetrische synthese von alpha-substituierten alpha-cyanomethylalkoholen. Expired - Fee Related DE3485403D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPG043283 1983-07-22
AUPG275883 1983-12-08

Publications (1)

Publication Number Publication Date
DE3485403D1 true DE3485403D1 (de) 1992-02-13

Family

ID=25642681

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484304951T Expired - Fee Related DE3485403D1 (de) 1983-07-22 1984-07-19 Asymmetrische synthese von alpha-substituierten alpha-cyanomethylalkoholen.

Country Status (5)

Country Link
EP (2) EP0132392B1 (de)
AU (1) AU576322B2 (de)
CA (1) CA1258075A (de)
DE (1) DE3485403D1 (de)
GB (2) GB2143823B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4723027A (en) * 1982-11-22 1988-02-02 E. I. Du Pont De Nemours And Company Preparation of optically active alpha-hydroxynitriles
NZ206106A (en) * 1982-11-22 1987-10-30 Shell Oil Co Processes for the preparation of optically active cyanomethyl esters of alpha-chiral carboxylic acids and optionally substituted s-alpha-cyano-3-phenoxybenzyl alcohol
US4554102A (en) * 1983-09-26 1985-11-19 Shell Oil Company Cyanohydrination catalyst comprising non-crystalline or amorphous dipeptide
US4761494A (en) * 1984-08-20 1988-08-02 E. I. Du Pont De Nemours And Company Preparation of cyanomethyl esters
US4611076A (en) * 1985-06-26 1986-09-09 Shell Oil Company Chiral cyanohydrination process
US4611077A (en) * 1985-06-26 1986-09-09 Shell Oil Company Increasing enantiomeric selectivity in chiral cyanohydrination
IL88618A (en) * 1988-12-07 1993-02-21 Bromine Compounds Ltd Chiral cyanohydrination of m-phenoxybenzaldehyde over polymer-supported cyclo (phenylalanyl- histidine)
US5187296A (en) * 1988-12-07 1993-02-16 Bromine Compounds Limited Cyanohydrination process
JP2924000B2 (ja) * 1989-09-29 1999-07-26 住友化学工業株式会社 不斉誘起触媒
US7026322B2 (en) 1998-11-12 2006-04-11 Nereus Pharmaceuticals, Inc. Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds
US6358957B1 (en) * 1998-11-12 2002-03-19 Nereus Pharmaceuticals, Inc. Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds
CA2494049C (en) 2002-08-02 2011-10-18 Nereus Pharmaceuticals, Inc. Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
US7935704B2 (en) 2003-08-01 2011-05-03 Nereus Pharmaceuticals, Inc. Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
US7919497B2 (en) 2002-08-02 2011-04-05 Nereus Pharmaceuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use
GB0304132D0 (en) 2003-02-24 2003-03-26 Syngenta Ltd Chemical process
DE102004001271A1 (de) 2004-01-08 2005-08-04 Bayer Cropscience Ag Wirkstoffkombinationen mit insektiziden Eigenschaften
US8129527B2 (en) 2006-11-03 2012-03-06 Nereus Pharmacuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use
EP2127522A1 (de) 2008-05-29 2009-12-02 Bayer CropScience AG Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
DE102009028001A1 (de) 2009-07-24 2011-01-27 Bayer Cropscience Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
EP2382865A1 (de) 2010-04-28 2011-11-02 Bayer CropScience AG Synergistische Wirkstoffkombinationen
EP2446742A1 (de) 2010-10-28 2012-05-02 Bayer CropScience AG Insektizide oder akarizide Zusammensetzungen enthaltend Mono- oder Disacchariden als Wirkungsverstärker
CN102850257B (zh) * 2012-09-17 2015-09-30 山东方明药业集团股份有限公司 1,2-环戊烷二甲酰亚胺的制备方法
WO2016144635A1 (en) 2015-03-06 2016-09-15 Beyondspring Pharmaceuticals, Inc. Method of treating cancer associated with a ras mutation
US10076518B2 (en) 2015-03-06 2018-09-18 Beyondspring Pharmaceuticals, Inc. Method of treating a brain tumor
MY181892A (en) 2015-07-13 2021-01-12 Beyondspring Pharmaceuticals Inc Plinabulin compositions
SG11201806583XA (en) 2016-02-08 2018-09-27 Beyondspring Pharmaceuticals Inc Compositions containing tucaresol or its analogs
AU2017278245B2 (en) 2016-06-06 2022-09-15 Beyondspring Pharmaceuticals, Inc. Composition and method for reducing neutropenia
US11633393B2 (en) 2017-01-06 2023-04-25 Beyondspring Pharmaceuticals, Inc. Tubulin binding compounds and therapeutic use thereof
MY201811A (en) 2017-02-01 2024-03-19 Beyondspring Pharmaceuticals Inc Method of reducing neutropenia
SG11202006985TA (en) 2018-01-24 2020-08-28 Beyondspring Pharmaceuticals Inc Composition and method for reducing thrombocytopenia via the administration of plinabulin
CN109111373A (zh) * 2018-10-09 2019-01-01 南通天泽化工有限公司 一种三氟氯氰菊酯的制备方法
WO2022200364A1 (en) 2021-03-25 2022-09-29 Syngenta Crop Protection Ag Insect, acarina and nematode pest control
WO2022238575A1 (en) 2021-05-14 2022-11-17 Syngenta Crop Protection Ag Insect, acarina and nematode pest control
WO2022268815A1 (en) 2021-06-24 2022-12-29 Syngenta Crop Protection Ag Insect, acarina and nematode pest control
WO2022268813A1 (en) 2021-06-24 2022-12-29 Syngenta Crop Protection Ag Insect, acarina and nematode pest control
WO2023105064A1 (en) 2021-12-10 2023-06-15 Syngenta Crop Protection Ag Insect, acarina and nematode pest control
WO2023105065A1 (en) 2021-12-10 2023-06-15 Syngenta Crop Protection Ag Insect, acarina and nematode pest control

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS515450B1 (de) * 1971-06-29 1976-02-20
US4163787A (en) * 1977-03-14 1979-08-07 The Dow Chemical Company Substituted pyridine methyl esters of cyclopropane carboxylic acids and their use as insecticides
ZA7911B (en) * 1978-01-31 1980-01-30 Roussel Uclaf Optically-active substituted benzyl alcohol and process for preparing it
FR2526017B1 (fr) * 1982-04-30 1985-10-11 Roussel Uclaf Ester d'acide cyclopropane carboxylique et d'alcool (s) cyano (4-fluoro 3-phenoxyphenyl) methylique, son procede de preparation et les compositions pesticides le renfermant
NZ206106A (en) * 1982-11-22 1987-10-30 Shell Oil Co Processes for the preparation of optically active cyanomethyl esters of alpha-chiral carboxylic acids and optionally substituted s-alpha-cyano-3-phenoxybenzyl alcohol
US4529810A (en) * 1983-02-22 1985-07-16 Shell Oil Company Preparation of optically-active alpha-substituted carboxylic esters and acids
US4554102A (en) * 1983-09-26 1985-11-19 Shell Oil Company Cyanohydrination catalyst comprising non-crystalline or amorphous dipeptide

Also Published As

Publication number Publication date
AU3033184A (en) 1985-01-24
GB8418611D0 (en) 1984-08-22
AU576322B2 (en) 1988-08-25
EP0132392B1 (de) 1992-01-02
GB2143823A (en) 1985-02-20
EP0304954A2 (de) 1989-03-01
GB8701511D0 (en) 1987-02-25
EP0132392A3 (en) 1985-07-10
EP0304954A3 (de) 1989-07-26
GB2143823B (en) 1988-03-23
EP0132392A2 (de) 1985-01-30
GB2186280A (en) 1987-08-12
CA1258075A (en) 1989-08-01
GB2186280B (en) 1988-03-23

Similar Documents

Publication Publication Date Title
DE3485403D1 (de) Asymmetrische synthese von alpha-substituierten alpha-cyanomethylalkoholen.
ATE46512T1 (de) Verfahren zur synthese von pyridoimidazorifamycin.
DE68923255D1 (de) Synthese von Methylaluminoxanen.
DE3675169D1 (de) Herstellung von tabletten.
DE3579719D1 (de) Herstellung von emulsionen.
ATE123037T1 (de) Synthese von carbonylverbindungen.
DE3672236D1 (de) Synthese von zeolithen.
DE3787247D1 (de) Klassifizierung von Sprachbandsignalen.
DE3689304D1 (de) Synthese von Verbindungen vom Podophylotoxintyp.
DE3787249D1 (de) Klassifizierung von Sprachbandsignalen.
FI863517A0 (fi) Stabilisering.
DE3586114D1 (de) Synthese von ammoniak.
FI870170A (fi) Vaermestabila finfoerdelade artificiella soetningsmedel.
DE3584503D1 (de) Herstellung von emulsionen.
ES2025154B3 (es) Sintesis del amoniaco.
DE3575510D1 (de) Vorbearbeitung von zweistufigen bilddaten.
DE3482556D1 (de) Synthese von silicophosphoaluminaten.
DE3674886D1 (de) Entfernen von katalysatorresten aus ethen/co-copolymeren.
IT8619378A0 (it) Procedimento per omopolimerizzazione anionica di alfa-trifluorometilacrilato.
IT8224183A0 (it) Prodotto per interrompere la dormitura di germogli.
IT8522977A0 (it) Purificiazione di l-fenilalanina.
DE3781345D1 (de) Synthese eines zeoliths.
DE69006345D1 (de) Totale Synthese von Erbstatin-Analogen.
IT1208493B (it) Analoghi di ossaprostaglandina 7-ossabicicloeptano sostituiti.
ES2023930B3 (es) Sintesis de ditioles.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee