DE3484212D1 - Hybride dns-synthese von reifem wachstumshormonausloesendem faktor. - Google Patents
Hybride dns-synthese von reifem wachstumshormonausloesendem faktor.Info
- Publication number
- DE3484212D1 DE3484212D1 DE8484105666T DE3484212T DE3484212D1 DE 3484212 D1 DE3484212 D1 DE 3484212D1 DE 8484105666 T DE8484105666 T DE 8484105666T DE 3484212 T DE3484212 T DE 3484212T DE 3484212 D1 DE3484212 D1 DE 3484212D1
- Authority
- DE
- Germany
- Prior art keywords
- growth hormone
- hormone releasing
- releasing factor
- dna synthesis
- hybrid dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 102000038461 Growth Hormone-Releasing Hormone Human genes 0.000 title abstract 2
- 239000000095 Growth Hormone-Releasing Hormone Substances 0.000 title abstract 2
- 101710142969 Somatoliberin Proteins 0.000 title abstract 2
- 230000006820 DNA synthesis Effects 0.000 title 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49777683A | 1983-05-25 | 1983-05-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3484212D1 true DE3484212D1 (de) | 1991-04-11 |
Family
ID=23978259
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8484105666T Expired - Fee Related DE3484212D1 (de) | 1983-05-25 | 1984-05-18 | Hybride dns-synthese von reifem wachstumshormonausloesendem faktor. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0129073B1 (de) |
JP (1) | JPS59227899A (de) |
AT (1) | ATE61405T1 (de) |
DE (1) | DE3484212D1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7198919B1 (en) | 1983-04-25 | 2007-04-03 | Genentech, Inc. | Use of alpha factor sequences in yeast expression systems |
NZ207926A (en) * | 1983-04-25 | 1988-04-29 | Genentech Inc | Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast |
IT1234977B (it) | 1985-03-22 | 1992-06-09 | Serono Ist Farm | Espressione in e. coli polipeptidi ibridi contenenti la sequenza del fattore di rilascio dell'ormone della crescita |
FR2593518B1 (fr) * | 1985-05-02 | 1989-09-08 | Transgene Sa | Vecteurs d'expression et de secretion de l'hirudine par les levures transformees |
US5821079A (en) * | 1985-05-02 | 1998-10-13 | Transgene S.A. | Vectors for the expression and secretion of hirudin by transformed yeasts |
FR2587359B1 (fr) * | 1985-05-28 | 1987-12-24 | Sanofi Sa | Derives non amides de la somatocrinine et procede de preparation par genie genetique |
GB8513645D0 (en) * | 1985-05-30 | 1985-07-03 | Kingsman A J | Expression vector |
JPS6236183A (ja) * | 1985-06-20 | 1987-02-17 | ザ・サルク・インステイチユ−ト・バイオテクノロジ−/インダストリアル・アソシエイツ・インコ−ポレ−テツド | サツカロミセス・セレビシエからのポリペプチドの発現および分泌 |
DE3540075A1 (de) * | 1985-11-12 | 1987-05-14 | Boehringer Ingelheim Int | Human-lysozym |
EP0234862A3 (de) * | 1986-02-28 | 1988-10-05 | Merck & Co. Inc. | Expression rekombinanter Proteine in Hefe |
EP0234871A3 (de) * | 1986-02-28 | 1988-10-12 | Merck & Co. Inc. | Regulierbare Expression rekombinanter Proteine in Hefe |
US4828988A (en) * | 1986-05-15 | 1989-05-09 | Smith Kline - Rit | Hybrid polypeptides comprising somatocrinine and alpha1 -antitrypsin, method for their production from bacterial clones and use thereof for the production of somatocrinine |
FR2599380A1 (fr) * | 1986-05-29 | 1987-12-04 | Centre Nat Rech Scient | Vecteur d'exportation de proteines chez escherichiacoli, bacteries transformees et procede pour la preparation de proteines |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3381567D1 (de) * | 1982-11-04 | 1990-06-21 | Hoffmann La Roche | Hestellung von rekombinanten wachstumsausloesenden faktoren. |
-
1984
- 1984-05-11 JP JP59093070A patent/JPS59227899A/ja active Pending
- 1984-05-18 EP EP84105666A patent/EP0129073B1/de not_active Expired - Lifetime
- 1984-05-18 AT AT84105666T patent/ATE61405T1/de not_active IP Right Cessation
- 1984-05-18 DE DE8484105666T patent/DE3484212D1/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0129073A1 (de) | 1984-12-27 |
JPS59227899A (ja) | 1984-12-21 |
ATE61405T1 (de) | 1991-03-15 |
EP0129073B1 (de) | 1991-03-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3484212D1 (de) | Hybride dns-synthese von reifem wachstumshormonausloesendem faktor. | |
ZA874605B (en) | Process for the genetic modification of yeast | |
HUT47974A (en) | Process for producing polypeptide | |
EP0256421A3 (de) | Sekretion heterologer Proteine von Hefe | |
DE3485444D1 (de) | Hybrid-dns-synthese von insulin. | |
EP0494702A3 (en) | Production of factor xiiia by gene technology | |
ES8602137A1 (es) | Procedimiento para obtener una proteina heterologa para levaduras | |
AU1322692A (en) | Method for the in vitro production of protein from a dna sequence without cloning | |
DE3851462D1 (de) | Verfahren zur Herstellung eines supraleitenden Materials des Oxydverbundtyps. | |
DE3770084D1 (de) | Pulverfoermiges rohmaterial fuer die herstellung von anoden von brennstoffzellen. | |
DE3871410D1 (de) | (phenylethenyl)phenylpropionaldehyd und verfahren zur herstellung von (benzoylphenyl)propionsaeure unter verwendung dieser verbindung. | |
IE872420L (en) | Preparing antibiotic a40926 complex | |
IL72701A0 (en) | Recombinant process for preparing l-amino acids | |
EP0149241A3 (en) | Dna base sequence containing regions involved in the production and secretion of a protein, recombinant dna including the whole or a part of the dna base sequence, and method of producing proteins by use of the recombinant dna | |
EP0152483A4 (de) | Verfahren zur herstellung von peptiden. | |
IL82207A0 (en) | Production of peptides,recombinant plasmid used therefor and animal cells transformed therewith | |
DE3565522D1 (en) | Process for the separation of concentrated ethylene glycol in a proces for the production of ethylene oxide | |
AU1090688A (en) | Synthetic porcine growth hormone | |
GB2152503B (en) | Process for producing l-phenylalanine | |
AU5309586A (en) | Polypeptide secretion-causing vector, microorganisms transformed by said vector, and process for preparing polypeptide using said microorganisms | |
EP0304971A3 (de) | Verfahren zur Herstellung eines Polypeptids mit der Proteasehemmenden Aktivität von Säugetier-alpha-1-Antitrypsin | |
EP0239075A3 (de) | Verfahren zur Herstellung eines Fischwachstumshormon-Polypeptids | |
ATA370885A (de) | Verfahren zur herstellung neuer mikroorganismen zur produktion von hybriden human-leukozyten-interferonen | |
GR3001086T3 (en) | Substituted dioxanones, method for preparing same and use thereof | |
FI953141A (fi) | Menetelmä soluissa tuotettavan HIV:n glykoproteiinin GP 160 eristämiseksi ja puhdistamiseksi |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |