DE3483087D1 - Monosaccharide verbindungen mit immunostimulierender wirkung. - Google Patents

Monosaccharide verbindungen mit immunostimulierender wirkung.

Info

Publication number
DE3483087D1
DE3483087D1 DE8484902242T DE3483087T DE3483087D1 DE 3483087 D1 DE3483087 D1 DE 3483087D1 DE 8484902242 T DE8484902242 T DE 8484902242T DE 3483087 T DE3483087 T DE 3483087T DE 3483087 D1 DE3483087 D1 DE 3483087D1
Authority
DE
Germany
Prior art keywords
immunostimulating effect
monosaccharide compounds
monosaccharide
compounds
immunostimulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8484902242T
Other languages
English (en)
Inventor
R Raetz
Laurens Anderson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Application granted granted Critical
Publication of DE3483087D1 publication Critical patent/DE3483087D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
DE8484902242T 1983-05-06 1984-05-02 Monosaccharide verbindungen mit immunostimulierender wirkung. Expired - Lifetime DE3483087D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49237883A 1983-05-06 1983-05-06
PCT/US1984/000670 WO1984004526A1 (en) 1983-05-06 1984-05-02 Monosaccharide compounds having immunostimulating activity

Publications (1)

Publication Number Publication Date
DE3483087D1 true DE3483087D1 (de) 1990-10-04

Family

ID=23956030

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484902242T Expired - Lifetime DE3483087D1 (de) 1983-05-06 1984-05-02 Monosaccharide verbindungen mit immunostimulierender wirkung.

Country Status (4)

Country Link
EP (1) EP0143840B1 (de)
JP (1) JPS60501259A (de)
DE (1) DE3483087D1 (de)
WO (1) WO1984004526A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004881A1 (en) * 1984-04-21 1985-11-07 Sandoz Ag 2,3-dinamo-2,3-didesoxyhexose derivatives, processes for their preparation and their use
US5066794A (en) * 1984-08-24 1991-11-19 Daiichi Pharmaceutical Co., Ltd. Process for preparing a disaccharide derivative
WO1986005687A1 (en) * 1985-04-03 1986-10-09 Wisconsin Alumni Research Foundation Method of preventing diseases caused by gram-negative endotoxin in mammals
NL8601551A (nl) * 1985-06-28 1987-01-16 Sandoz Ag Nieuwe saccharides, hun bereiding en farmaceutische samenstellingen, die hen bevatten.
DE3731953A1 (de) * 1987-09-23 1989-04-06 Sandoz Ag Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung
US4746742A (en) * 1985-11-28 1988-05-24 Toho Yakuhin Kogyo Kabushiki Kaisha Analogs of nonreducing monosaccharide moiety of lipid A
ES2032386T3 (es) * 1985-12-06 1993-02-16 Ono Pharmaceutical Co., Ltd. Un procedimiento para la preparacion de un derivado de glucopiranosa.
USRE36385E (en) * 1985-12-06 1999-11-09 Ono Pharmaceutical Co., Ltd. Glucopyranose derivatives
US4925929A (en) * 1985-12-06 1990-05-15 Ono Pharmaceutical Co. Ltd. Glucopyranose derivatives
AT387780B (de) * 1986-06-24 1989-03-10 Sandoz Ag Verfahren zur herstellung neuer saccharide
DE3886085T2 (de) * 1987-05-01 1994-06-23 Ono Pharmaceutical Co Glucopyranose-Derivate.
US5597573A (en) * 1989-05-04 1997-01-28 Igen, Inc. Lipid-A analogs: new monosaccharide and disaccharide intermediates for eliciting therapeutic antibodies and for antitumor and antiviral activities
JPH0655749B2 (ja) * 1989-09-20 1994-07-27 日本たばこ産業株式会社 リピッドａ単糖類縁体
PT94481B (pt) * 1989-12-11 1997-02-28 Sankyo Co Processo para a preparacao de analogos de lipidos a tendo imunoactividade e actividade anti-tumoral
CA2059272A1 (en) * 1990-04-12 1991-10-13 Akira Hasegawa 4,6-0-hydroxyphosphoryl-glucosamine derivatives
US5158941A (en) * 1990-06-08 1992-10-27 E. I. Du Pont De Nemours And Company Lipid A analog as stimulant for production of interleukin-1 in human monocytes and tumor cell growth inhibitor
US5593969A (en) * 1991-09-03 1997-01-14 Igen Incorporated Lipid-A analogs: monosaccharide and dissaccharide compounds for inhibiting binding of lipid A receptors to lipid A receptors
NO178729C (no) * 1992-03-31 1996-05-22 Daiichi Seiyaku Co Terapeutisk aktive sukkerderivater
US6368604B1 (en) 1997-09-26 2002-04-09 University Of Maryland Biotechnology Institute Non-pyrogenic derivatives of lipid A
EP1104767A1 (de) * 1999-11-30 2001-06-06 Stichting Dienst Landbouwkundig Onderzoek Mono- und Disaccharidederivate die sowohl Fettsäureestern als Sulfatestern enthalten
WO2017031431A1 (en) * 2015-08-19 2017-02-23 President And Fellows Of Harvard College Lipidated psa compositions and methods
US10905783B2 (en) 2015-11-27 2021-02-02 Michal RIVLIN Glucosamine and derivatives thereof in imaging
US11491181B2 (en) 2016-07-15 2022-11-08 President And Fellows Of Harvard College Glycolipid compositions and methods of use

Also Published As

Publication number Publication date
EP0143840B1 (de) 1990-08-29
EP0143840A1 (de) 1985-06-12
WO1984004526A1 (en) 1984-11-22
EP0143840A4 (de) 1986-02-13
JPS60501259A (ja) 1985-08-08

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