DE3478468D1 - A substrate comprising regenerated collagen fibrils - Google Patents

A substrate comprising regenerated collagen fibrils

Info

Publication number
DE3478468D1
DE3478468D1 DE8484301602T DE3478468T DE3478468D1 DE 3478468 D1 DE3478468 D1 DE 3478468D1 DE 8484301602 T DE8484301602 T DE 8484301602T DE 3478468 T DE3478468 T DE 3478468T DE 3478468 D1 DE3478468 D1 DE 3478468D1
Authority
DE
Germany
Prior art keywords
substrate
collagen fibrils
regenerated collagen
regenerated
fibrils
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484301602T
Other languages
English (en)
Inventor
Teruo Miyata
Shin Ichi Namiki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koken Co Ltd
Original Assignee
Koken Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koken Co Ltd filed Critical Koken Co Ltd
Application granted granted Critical
Publication of DE3478468D1 publication Critical patent/DE3478468D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C12N5/0075—General culture methods using substrates using microcarriers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE8484301602T 1983-03-10 1984-03-09 A substrate comprising regenerated collagen fibrils Expired DE3478468D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58039597A JPS59164723A (ja) 1983-03-10 1983-03-10 再生コラーゲンフイブリルを含有する基質及びその製造方法

Publications (1)

Publication Number Publication Date
DE3478468D1 true DE3478468D1 (en) 1989-07-06

Family

ID=12557515

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484301602T Expired DE3478468D1 (en) 1983-03-10 1984-03-09 A substrate comprising regenerated collagen fibrils

Country Status (4)

Country Link
US (1) US4565580A (de)
EP (1) EP0119076B1 (de)
JP (1) JPS59164723A (de)
DE (1) DE3478468D1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE454518B (sv) * 1984-05-21 1988-05-09 Statens Bakteriologiska Lab Forfarande for odling av diploida celler i nervaro av cellulosafibrer
JPS61122222A (ja) * 1984-11-19 1986-06-10 Koken:Kk コラ−ゲン又はゼラチンとプロタミンとよりなる止血剤
JPS61230728A (ja) * 1985-04-06 1986-10-15 Koken:Kk アシル化コラ−ゲンまたはアシル化ゼラチンからなる界面活性剤及びその製造方法
SE464816B (sv) * 1985-10-15 1991-06-17 Nilsson Kjell Makroporoesa partiklar, foerfarande foer dess framstaellning och dess anvaendning
FR2597499A1 (fr) * 1986-04-18 1987-10-23 Merieux Inst Procede de culture microbiologique sur supports de collagene, supports pour ce procede et produits obtenus
DE68913890T2 (de) * 1988-04-18 1994-08-04 Nitta Gelatin Kk Verfahren zur züchtung tierischer zellen in grossem massstab und verfahren zur herstellung von trägermaterial dafür.
US5258028A (en) * 1988-12-12 1993-11-02 Ersek Robert A Textured micro implants
US5219895A (en) * 1991-01-29 1993-06-15 Autogenesis Technologies, Inc. Collagen-based adhesives and sealants and methods of preparation and use thereof
WO1993019702A1 (en) * 1992-04-06 1993-10-14 Uroplasty, Inc. Treatment of reflux disorder by microparticles injection
WO1994009831A1 (en) * 1992-11-02 1994-05-11 Nippon Meat Packers, Inc. Topically absorbent hemostatic material
US5656492A (en) * 1993-02-12 1997-08-12 Brigham And Women's Hospital, Inc. Cell induction device
US5316942A (en) * 1993-06-16 1994-05-31 Battelle Memorial Institute Process for the production of low-cost soluble high-molecular weight collagen
US5707491A (en) * 1993-06-16 1998-01-13 Ranpak Corporation Paper strengthened with solubilized collagen and method
US5711853A (en) * 1993-06-16 1998-01-27 Ranpak Corp. Paper strengthened with solubilized collagen and method
US5700354A (en) * 1993-06-16 1997-12-23 Ranpak Corp. Paper strengthened with solubilized collagen and method
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
DE19934894A1 (de) * 1999-07-24 2001-02-01 Pharma Concepts Gmbh & Co Kg Verfahren zur Herstellung von Kollagenpartikeln
US6183498B1 (en) 1999-09-20 2001-02-06 Devore Dale P. Methods and products for sealing a fluid leak in a tissue
US9080146B2 (en) * 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
US20080226723A1 (en) * 2002-07-05 2008-09-18 Celonova Biosciences, Inc. Loadable Polymeric Particles for Therapeutic Use in Erectile Dysfunction and Methods of Preparing and Using the Same
US7544381B2 (en) * 2003-09-09 2009-06-09 Boston Scientific Scimed, Inc. Lubricious coatings for medical device
US9114162B2 (en) 2004-10-25 2015-08-25 Celonova Biosciences, Inc. Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same
US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
KR101153785B1 (ko) * 2004-10-25 2012-07-09 셀로노바 바이오사이언시스 저머니 게엠베하 치료 및/또는 진단용으로 부가할 수 있는 중합체 입자 및이의 제조 및 사용 방법
US9107850B2 (en) * 2004-10-25 2015-08-18 Celonova Biosciences, Inc. Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
US20060222680A1 (en) * 2005-03-31 2006-10-05 Chunlin Yang Method of preparing crosslinked collagen microspheres
US20090110738A1 (en) * 2007-10-26 2009-04-30 Celonova Biosciences, Inc. Loadable Polymeric Particles for Cosmetic and Reconstructive Tissue Augmentation Applications and Methods of Preparing and Using the Same
US20090111763A1 (en) * 2007-10-26 2009-04-30 Celonova Biosciences, Inc. Loadable polymeric particles for bone augmentation and methods of preparing and using the same
US20090110730A1 (en) * 2007-10-30 2009-04-30 Celonova Biosciences, Inc. Loadable Polymeric Particles for Marking or Masking Individuals and Methods of Preparing and Using the Same
US20090110731A1 (en) * 2007-10-30 2009-04-30 Celonova Biosciences, Inc. Loadable Polymeric Microparticles for Therapeutic Use in Alopecia and Methods of Preparing and Using the Same
FR3033697B1 (fr) 2015-03-17 2020-03-27 Universite Pierre Et Marie Curie (Paris 6) Suspensions de collagene injectables, leur procede de preparation et leurs utilisations, notamment pour la formation de matrices denses de collagene

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2935413A (en) * 1954-10-19 1960-05-03 Armour & Co Procollagen material
US2920000A (en) * 1955-11-07 1960-01-05 Ethicon Inc Ethicon Inc Removable valve Collagen article and the manufacture thereof
US2919998A (en) * 1957-11-07 1960-01-05 Ethicon Inc Collagen article and the manufacture thereof
US2919999A (en) * 1958-10-22 1960-01-05 Ethicon Inc Collagen article and the manufacture thereof
US3071483A (en) * 1960-05-03 1963-01-01 United Shoe Machinery Corp Manufacture of collagen products
US3551535A (en) * 1964-12-01 1970-12-29 Union Carbide Corp Freezing-mixing process for making homogeneous collagen mixtures
FR1567174A (de) * 1968-02-12 1969-05-16
US3632361A (en) * 1969-06-26 1972-01-04 Fmc Corp Water-insoluble microcrystalline collagen absorbent mat
US3806350A (en) * 1969-07-28 1974-04-23 Freudenberg C Fiber-reinforced collagen composition and process for preparing same
JPS5547130A (en) * 1978-09-28 1980-04-03 Nippi:Kk Manufacture of collagen bead
DE2929144A1 (de) * 1979-07-19 1981-02-12 Behringwerke Ag Verfahren zur herstellung von kollagen
US4279812A (en) * 1979-09-12 1981-07-21 Seton Company Process for preparing macromolecular biologically active collagen
SE445116B (sv) * 1979-09-12 1986-06-02 Pharmacia Fine Chemicals Ab Sett att odla celler pa mikroberare med fibronektinytskikt
FR2470794A1 (fr) * 1979-12-05 1981-06-12 Pasteur Institut Nouvelles microparticules, leur preparation et leurs applications en biologie, notamment a la culture de cellules diploides humaines
SE456164B (sv) * 1980-08-20 1988-09-12 Kjell Nilsson Forfarande for immobilisering, odling och efterfoljande frigoring av animala celler samt mikroberare av gelatin med absorberade animala celler
US4420339A (en) * 1981-03-27 1983-12-13 Kureha Kagaku Kogyo Kabushiki Kaisha Collagen fibers for use in medical treatments
EP0097907A3 (de) * 1982-06-25 1985-01-09 Flow General, Inc. Mikroträger für Zellkultur

Also Published As

Publication number Publication date
JPH043949B2 (de) 1992-01-24
EP0119076A2 (de) 1984-09-19
JPS59164723A (ja) 1984-09-17
EP0119076B1 (de) 1989-05-31
US4565580A (en) 1986-01-21
EP0119076A3 (en) 1986-07-23

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Legal Events

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8339 Ceased/non-payment of the annual fee