DE3474446D1 - Substituted 1-amino-4-nitro-acridinones, pharmaceutical compositions comprising the same and processes for their production - Google Patents

Substituted 1-amino-4-nitro-acridinones, pharmaceutical compositions comprising the same and processes for their production

Info

Publication number
DE3474446D1
DE3474446D1 DE8484307491T DE3474446T DE3474446D1 DE 3474446 D1 DE3474446 D1 DE 3474446D1 DE 8484307491 T DE8484307491 T DE 8484307491T DE 3474446 T DE3474446 T DE 3474446T DE 3474446 D1 DE3474446 D1 DE 3474446D1
Authority
DE
Germany
Prior art keywords
acridinones
nitro
amino
substituted
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484307491T
Other languages
English (en)
Inventor
David Bridgeman Capps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of DE3474446D1 publication Critical patent/DE3474446D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8484307491T 1983-11-08 1984-10-31 Substituted 1-amino-4-nitro-acridinones, pharmaceutical compositions comprising the same and processes for their production Expired DE3474446D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54970983A 1983-11-08 1983-11-08
US06/658,100 US4626540A (en) 1983-11-08 1984-10-10 Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them

Publications (1)

Publication Number Publication Date
DE3474446D1 true DE3474446D1 (en) 1988-11-10

Family

ID=27069207

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484307491T Expired DE3474446D1 (en) 1983-11-08 1984-10-31 Substituted 1-amino-4-nitro-acridinones, pharmaceutical compositions comprising the same and processes for their production

Country Status (8)

Country Link
US (1) US4626540A (de)
EP (1) EP0145226B1 (de)
AU (1) AU573639B2 (de)
CA (1) CA1258856A (de)
DE (1) DE3474446D1 (de)
DK (1) DK529484A (de)
ES (1) ES537440A0 (de)
GR (1) GR80846B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340818A (en) * 1989-05-25 1994-08-23 Sloan-Kettering Institute For Cancer Research Methods and compositions for inhibiting tumor cell growth
GB8923075D0 (en) * 1989-10-13 1989-11-29 Patterson Laurence H Anti-cancer compounds
GB9104548D0 (en) 1991-03-05 1991-04-17 Cholody Wienlaw M Antineoplastic modified imidazoacridines
US5296602A (en) * 1991-03-18 1994-03-22 Sloan-Kettering Institute For Cancer Research Multisubstituted 1-hydroxy-9-acridones with anticancer activity
GB9107852D0 (en) * 1991-04-12 1991-05-29 Patterson Laurence H Anti-cancer compounds
GB9107843D0 (en) * 1991-04-12 1991-05-29 Patterson Laurence H Anti-cancer compounds
FR2716454A1 (fr) * 1994-02-22 1995-08-25 Pf Medicament Nouveaux dérivés de 4-aminométhyl 3-diméthylamino acridines substituées, leur préparation et leur application thérapeutique.
US5508289A (en) * 1994-03-14 1996-04-16 The United States America As Represented By The Department Of Health And Human Services Bis-acridone chemotherapeutic derivatives
RU2103006C1 (ru) * 1995-03-23 1998-01-27 Олег Викторович Травкин Иммуномодулирующее лекарственное средство
AU7456396A (en) * 1995-11-02 1997-05-22 Warner-Lambert Company Inhibition of amyloidosis by 9-acridinones
US7781396B2 (en) * 2002-01-31 2010-08-24 Tel Aviv University Future Technology Development L.P. Peptides directed for diagnosis and treatment of amyloid-associated disease
US20040052928A1 (en) * 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
US7491699B2 (en) * 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
EP1583713B1 (de) 2003-01-07 2009-03-25 Ramot at Tel Aviv University Ltd. Peptidenanostrukturen die fremdmaterial enthalten, und verfahren zur herstellung derselben
CA2530927A1 (en) 2003-06-30 2005-01-06 Tel Aviv University Future Technology Development L.P. Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases
WO2005027901A1 (en) 2003-09-25 2005-03-31 Tel Aviv University Future Technology Development L.P. Compositions and methods using same for treating amyloid-associated diseases
US7625707B2 (en) * 2003-10-02 2009-12-01 Ramot At Tel Aviv University Ltd. Antibacterial agents and methods of identifying and utilizing same
US8007847B2 (en) 2004-01-13 2011-08-30 Eytan Biderman Feeding formula appliance
WO2006006172A2 (en) * 2004-07-15 2006-01-19 Ramot At Tel Aviv University Ltd. Use of anti-amyloid agents for treating and typing pathogen infections
US8568637B2 (en) 2004-08-02 2013-10-29 Ramot At Tel-Aviv University Ltd. Method of forming a fiber made of peptide nanostructures
EP1793816B1 (de) 2004-08-19 2012-01-04 Tel Aviv University Future Technology Development L.P. Zusammensetzungen zur behandlung von amyloid-assoziierten erkrankungen
WO2006027780A2 (en) 2004-09-08 2006-03-16 Ramot At Tel Aviv University Ltd. Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same
JP2008527563A (ja) 2005-01-16 2008-07-24 ズランゴー リミテッド アイコニック通信
US8019818B2 (en) 2005-01-18 2011-09-13 Zlango Ltd. Communications network system and methods for using same
EP1973928A2 (de) 2005-10-11 2008-10-01 Ramot at Tel-Aviv University Ltd. Selbstzusammengebaute fmoc-ff-hydrogele
US7879212B2 (en) * 2005-11-03 2011-02-01 Ramot At Tel-Aviv University Ltd. Peptide nanostructure-coated electrodes
US8775526B2 (en) 2006-01-16 2014-07-08 Zlango Ltd. Iconic communication
JP5911503B2 (ja) 2010-11-15 2016-04-27 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッドＲａｍｏｔ Ａｔ Ｔｅｌ Ａｖｉｖ Ｕｎｉｖｅｒｓｉｔｙ Ｌｔｄ． アミロイド線維形成関連状態を処置するためのジペプチドアナログ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2647901A (en) * 1952-05-06 1953-08-04 Sterling Drug Inc 1-(tertiary-aminoalkylamino) acridones and their method of preparation
DE2342723A1 (de) * 1973-08-24 1975-04-10 Bayer Ag Transferdruckverfahren
PL101032B1 (pl) * 1976-04-06 1978-11-30 Sposob otrzymywania 1-nitro-9-dwualkilo-aminoizoalkiloamiroakrydyn lub ich soli
FI833651A (fi) * 1982-10-11 1984-04-12 Hoechst Ag 3-aryl-7-klor-3,4-dihydro-akridin-1,9-(2h,1oh)-dion-1-oximer och -l-hydrazonderivat, deras salter,foerfarande foer deras framstaellning, dessa innehaollande aemnen och deras anvaending

Also Published As

Publication number Publication date
CA1258856A (en) 1989-08-29
EP0145226A3 (en) 1985-07-10
AU573639B2 (en) 1988-06-16
US4626540A (en) 1986-12-02
EP0145226B1 (de) 1988-10-05
EP0145226A2 (de) 1985-06-19
DK529484A (da) 1985-05-09
GR80846B (en) 1985-03-04
ES8603425A1 (es) 1985-12-16
DK529484D0 (da) 1984-11-07
AU3513184A (en) 1985-05-16
ES537440A0 (es) 1985-12-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee