DE3468883D1 - Macrolide derivatives - Google Patents

Macrolide derivatives

Info

Publication number
DE3468883D1
DE3468883D1 DE8484301335T DE3468883T DE3468883D1 DE 3468883 D1 DE3468883 D1 DE 3468883D1 DE 8484301335 T DE8484301335 T DE 8484301335T DE 3468883 T DE3468883 T DE 3468883T DE 3468883 D1 DE3468883 D1 DE 3468883D1
Authority
DE
Germany
Prior art keywords
macrolide derivatives
macrolide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484301335T
Other languages
German (de)
English (en)
Inventor
Richard Henry Baltz
Jan Ross Turner
Veronica Marie Krupinski
David Shuichi Fukuda
Earl Eugene Ose
Barbara Buckley Shreve
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/471,928 external-priority patent/US4522919A/en
Priority claimed from US06/471,628 external-priority patent/US4559301A/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE3468883D1 publication Critical patent/DE3468883D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE8484301335T 1983-03-03 1984-03-01 Macrolide derivatives Expired DE3468883D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47163083A 1983-03-03 1983-03-03
US06/471,928 US4522919A (en) 1983-03-03 1983-03-03 Method of producing antibacterial agents and bioconverting microorganism therefor
US06/471,628 US4559301A (en) 1983-03-03 1983-03-03 Process for preparing macrocin derivatives

Publications (1)

Publication Number Publication Date
DE3468883D1 true DE3468883D1 (en) 1988-02-25

Family

ID=27413185

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484301335T Expired DE3468883D1 (en) 1983-03-03 1984-03-01 Macrolide derivatives

Country Status (11)

Country Link
EP (1) EP0121328B1 (instruction)
KR (1) KR860001820B1 (instruction)
DE (1) DE3468883D1 (instruction)
DK (1) DK144084A (instruction)
ES (1) ES530219A0 (instruction)
FI (1) FI840823A7 (instruction)
GB (1) GB2136424A (instruction)
GR (1) GR81513B (instruction)
HU (1) HUT36184A (instruction)
IL (1) IL71122A (instruction)
PT (1) PT78176B (instruction)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952502A (en) * 1987-02-24 1990-08-28 Eli Lilly And Company Carbomycin biosynthetic gene, designated carG, for use in streptomyces and other organisms
JP2749616B2 (ja) * 1988-05-24 1998-05-13 メルシャン株式会社 マクロライド抗生物質の４”位アシル化酵素をコードする遺伝子
GB0025556D0 (en) * 2000-10-18 2000-12-06 Eco Animal Health Ltd Treatment and prophylaxis of disease and infections of pigs and poultry
CN104610403B (zh) * 2015-01-23 2017-09-19 中牧实业股份有限公司 一种超级泰乐菌素的提纯方法
CN110684065B (zh) * 2019-10-24 2020-11-20 中牧实业股份有限公司 3-乙酰去碳霉糖泰乐菌素药用盐的制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3326759A (en) * 1962-07-19 1967-06-20 Lilly Co Eli Antibiotics macrocin and lactenocin
US4092473A (en) * 1975-08-01 1978-05-30 Sanraku Ocean Co., Ltd. Tylosin derivatives and their manufacturing process
US4205163A (en) * 1977-11-08 1980-05-27 Sanraku-Ocean Co., Ltd. Tylosin derivatives
US4385116A (en) * 1980-07-15 1983-05-24 Eli Lilly And Company Demethylmacrocin and process for its production

Also Published As

Publication number Publication date
HUT36184A (en) 1985-08-28
ES8602130A1 (es) 1985-11-16
IL71122A0 (en) 1984-06-29
GR81513B (instruction) 1984-12-11
KR860001820B1 (ko) 1986-10-24
ES530219A0 (es) 1985-11-16
DK144084D0 (da) 1984-02-29
EP0121328B1 (en) 1988-01-20
PT78176B (en) 1986-08-05
GB2136424A (en) 1984-09-19
IL71122A (en) 1986-12-31
EP0121328A2 (en) 1984-10-10
KR840008164A (ko) 1984-12-13
GB8405460D0 (en) 1984-04-04
EP0121328A3 (en) 1985-01-09
PT78176A (en) 1984-04-01
FI840823A7 (fi) 1984-09-04
DK144084A (da) 1984-09-04
FI840823A0 (fi) 1984-03-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee