DE3462890D1 - Pyridazinones, their preparation and use, medicines containing these pyridazinones - Google Patents
Pyridazinones, their preparation and use, medicines containing these pyridazinonesInfo
- Publication number
- DE3462890D1 DE3462890D1 DE8484105291T DE3462890T DE3462890D1 DE 3462890 D1 DE3462890 D1 DE 3462890D1 DE 8484105291 T DE8484105291 T DE 8484105291T DE 3462890 T DE3462890 T DE 3462890T DE 3462890 D1 DE3462890 D1 DE 3462890D1
- Authority
- DE
- Germany
- Prior art keywords
- pyridazinones
- pct
- preparation
- denotes
- sec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003814 drug Substances 0.000 title abstract 2
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical class OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title 2
- 229940079593 drug Drugs 0.000 title 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000000572 bronchospasmolytic effect Effects 0.000 abstract 1
- 239000000496 cardiotonic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/18—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH258183 | 1983-05-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3462890D1 true DE3462890D1 (en) | 1987-05-07 |
Family
ID=4237009
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3417391A Withdrawn DE3417391A1 (de) | 1983-05-11 | 1984-05-10 | Pyridazinone, ihre herstellung und verwendung, pyridazinone enthaltende arzneimittel |
| DE8484105291T Expired DE3462890D1 (en) | 1983-05-11 | 1984-05-10 | Pyridazinones, their preparation and use, medicines containing these pyridazinones |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3417391A Withdrawn DE3417391A1 (de) | 1983-05-11 | 1984-05-10 | Pyridazinone, ihre herstellung und verwendung, pyridazinone enthaltende arzneimittel |
Country Status (15)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK159431C (da) * | 1984-05-10 | 1991-03-18 | Byk Gulden Lomberg Chem Fab | 6-phenyl-3(2h)-pyridazinoner, fremgangsmaade til fremstilling deraf, laegemidler indeholdende disse samt anvendelse af forbindelserne til fremstilling af laegemidler |
| IL79280A (en) * | 1985-07-05 | 1990-07-12 | Smith Kline French Lab | 4-(6-oxo-dihydro or tetrahydropyridazin-3-yl)benzene derivatives,their preparation and pharmaceutical compositions containing them |
| DE3827362A1 (de) * | 1988-08-12 | 1990-02-15 | Basf Ag | Pulvrige, hydrophile theophyllinformulierung und verfahren zur ihrer herstellung |
| EP0393500A1 (de) * | 1989-04-17 | 1990-10-24 | Byk Gulden Lomberg Chemische Fabrik GmbH | Neue Arylpyridazine, ihre Herstellung, Verwendung und sie enthaltende Arzneimittel |
| CA2094127A1 (en) * | 1990-10-16 | 1992-04-17 | Hermann Amschler | Arylpyridazinones |
| EP0581805A1 (de) * | 1991-04-26 | 1994-02-09 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue pyridazine |
| WO1993000903A1 (de) * | 1991-07-05 | 1993-01-21 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Verwendung substituierter pyridazine gegen dermatosen |
| JP3100984B2 (ja) * | 1992-12-02 | 2000-10-23 | ファイザー・インク． | 選択的ｐｄｅ▲下ｉ▼▲下ｖ▼阻害物質としてのカテコールジエーテル類 |
| US5814651A (en) * | 1992-12-02 | 1998-09-29 | Pfizer Inc. | Catechol diethers as selective PDEIV inhibitors |
| DE19514568A1 (de) * | 1995-04-20 | 1996-10-24 | Merck Patent Gmbh | Arylalkyl-pyridazinone |
| ATE336254T1 (de) * | 1997-02-17 | 2006-09-15 | Altana Pharma Ag | Zusammensetzungen zur behandlung von irds oder ards die 3-(calcopropylmethoxy)-n-(3,5-dichloro-4-pyridi yl)-4-(difluoromethoxy) benzamid und lungensurfactant enthalten |
| US7437192B2 (en) * | 2005-04-05 | 2008-10-14 | Pacesetter, Inc. | System and method for detecting heart failure and pulmonary edema based on ventricular end-diastolic pressure using an implantable medical device |
| CN101668732A (zh) * | 2007-04-02 | 2010-03-10 | 同一世界健康研究院 | Cftr抑制剂化合物及其用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT343125B (de) * | 1976-03-24 | 1978-05-10 | Chemie Linz Ag | Verfahren zur herstellung von 3-phenylpyridazon- (6) |
| JPS6037101B2 (ja) * | 1977-03-09 | 1985-08-24 | 三共株式会社 | フエニルピリダジノン誘導体の製法 |
| US4397854A (en) * | 1981-05-14 | 1983-08-09 | Warner-Lambert Company | Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents |
| JPS588015A (ja) * | 1981-07-06 | 1983-01-18 | Mitsubishi Chem Ind Ltd | 強心剤 |
-
1984
- 1984-05-09 PT PT78566A patent/PT78566B/pt not_active IP Right Cessation
- 1984-05-09 ES ES532337A patent/ES532337A0/es active Granted
- 1984-05-09 NZ NZ208107A patent/NZ208107A/en unknown
- 1984-05-09 GR GR74656A patent/GR82072B/el unknown
- 1984-05-10 DE DE3417391A patent/DE3417391A1/de not_active Withdrawn
- 1984-05-10 EP EP84105291A patent/EP0125636B1/de not_active Expired
- 1984-05-10 AT AT84105291T patent/ATE26266T1/de not_active IP Right Cessation
- 1984-05-10 WO PCT/EP1984/000139 patent/WO1984004521A1/de unknown
- 1984-05-10 DE DE8484105291T patent/DE3462890D1/de not_active Expired
- 1984-05-10 JP JP59502040A patent/JPS60501258A/ja active Pending
- 1984-05-10 ZA ZA843520A patent/ZA843520B/xx unknown
- 1984-05-10 IL IL71788A patent/IL71788A/xx unknown
- 1984-05-10 AU AU29617/84A patent/AU560607B2/en not_active Ceased
- 1984-05-10 US US06/690,655 patent/US4707481A/en not_active Expired - Fee Related
- 1984-05-11 CA CA000454099A patent/CA1247100A/en not_active Expired
-
1985
- 1985-01-10 DK DK012485A patent/DK156655C/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE26266T1 (de) | 1987-04-15 |
| NZ208107A (en) | 1986-12-05 |
| CA1247100A (en) | 1988-12-20 |
| ZA843520B (en) | 1984-12-24 |
| DK156655B (da) | 1989-09-18 |
| ES8601918A1 (es) | 1985-12-01 |
| DK12485D0 (da) | 1985-01-10 |
| ES532337A0 (es) | 1985-12-01 |
| IL71788A (en) | 1987-09-16 |
| IL71788A0 (en) | 1984-09-30 |
| EP0125636B1 (de) | 1987-04-01 |
| GR82072B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-12-13 |
| PT78566B (de) | 1986-07-17 |
| WO1984004521A1 (en) | 1984-11-22 |
| DK12485A (da) | 1985-01-10 |
| DE3417391A1 (de) | 1984-11-15 |
| JPS60501258A (ja) | 1985-08-08 |
| PT78566A (de) | 1984-06-01 |
| DK156655C (da) | 1990-02-05 |
| AU560607B2 (en) | 1987-04-09 |
| EP0125636A1 (de) | 1984-11-21 |
| US4707481A (en) | 1987-11-17 |
| AU2961784A (en) | 1984-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |