DE3380627D1 - Cephem compounds, process and intermediates for their preparation and pharmaceutical compositions containing them - Google Patents

Cephem compounds, process and intermediates for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE3380627D1
DE3380627D1 DE8383106933T DE3380627T DE3380627D1 DE 3380627 D1 DE3380627 D1 DE 3380627D1 DE 8383106933 T DE8383106933 T DE 8383106933T DE 3380627 T DE3380627 T DE 3380627T DE 3380627 D1 DE3380627 D1 DE 3380627D1
Authority
DE
Germany
Prior art keywords
intermediates
preparation
pharmaceutical compositions
compositions containing
cephem compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383106933T
Other languages
English (en)
Inventor
Tsutomu Teraji
Kazuo Sakane
Jiro Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838305799A external-priority patent/GB8305799D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3380627D1 publication Critical patent/DE3380627D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE8383106933T 1982-07-19 1983-07-15 Cephem compounds, process and intermediates for their preparation and pharmaceutical compositions containing them Expired DE3380627D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8220833 1982-07-19
GB838305799A GB8305799D0 (en) 1983-03-02 1983-03-02 Cephem compounds

Publications (1)

Publication Number Publication Date
DE3380627D1 true DE3380627D1 (en) 1989-11-02

Family

ID=26283377

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8888102767T Expired - Fee Related DE3382621T2 (de) 1982-07-19 1983-07-15 Zwischenprodukte fuer die herstellung von cephemverbindungen, verfahren zu ihrer herstellung und ihre anwendung.
DE8383106933T Expired DE3380627D1 (en) 1982-07-19 1983-07-15 Cephem compounds, process and intermediates for their preparation and pharmaceutical compositions containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE8888102767T Expired - Fee Related DE3382621T2 (de) 1982-07-19 1983-07-15 Zwischenprodukte fuer die herstellung von cephemverbindungen, verfahren zu ihrer herstellung und ihre anwendung.

Country Status (4)

Country Link
US (3) US4563449A (de)
EP (2) EP0099553B1 (de)
JP (2) JPH0751591B2 (de)
DE (2) DE3382621T2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL74822A (en) * 1984-04-17 1989-06-30 Daiichi Seiyaku Co Cephalosporin derivatives and salts thereof and their preparation
CA1293719C (en) * 1986-09-22 1991-12-31 Takao Takaya Cephem compounds and processes for preparation thereof
DE3722539A1 (de) * 1987-07-08 1989-01-19 Reichenecker Hans Storopack Geschaeumter formkoerper
IE61679B1 (en) * 1987-08-10 1994-11-16 Fujisawa Pharmaceutical Co Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
US5958905A (en) 1996-03-26 1999-09-28 Texas Biotechnology Corporation Phosphoramidates, phosphinic amides and related compounds and the use thereof to modulate the activity of endothelin
KR100361829B1 (ko) * 1997-04-16 2005-08-17 주식회사 엘지생명과학 반응성 유기산 유도체로 부터 세프트리악손을 제조하는 방법
KR100361828B1 (ko) * 1997-04-16 2005-08-12 주식회사 엘지생명과학 반응성 유기산 유도체로 부터 세포탁심을 제조하는방법
TW473479B (en) * 1997-12-19 2002-01-21 Takeda Chemical Industries Ltd Phosphonocephem derivatives, their production and use
CN103945842A (zh) 2011-09-09 2014-07-23 丘比斯特药物股份有限公司 治疗肺内感染的方法
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US20140275000A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274995A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Parenteral ceftolozane antibiotic compositions
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE541421A (de) * 1954-10-26 1900-01-01
FR1210435A (fr) * 1958-09-26 1960-03-08 Cfmc Procédé de synthèse de la phosphocréatine
NL129633C (de) * 1965-03-05
FR1518199A (fr) * 1966-04-07 1968-03-22 Glaxo Lab Ltd Procédé de préparation d'antibiotiques du type de la céphalosporine
JPS5035079B1 (de) * 1970-10-17 1975-11-13
GB1391437A (en) * 1971-04-07 1975-04-23 Glaxo Lab Ltd Preparation of antibiotic compounds
US4268509A (en) * 1978-07-10 1981-05-19 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
AU536842B2 (en) * 1978-12-29 1984-05-24 Fujisawa Pharmaceutical Co., Ltd. Cephalosporin antibiotics
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Also Published As

Publication number Publication date
US4772682A (en) 1988-09-20
US4654422A (en) 1987-03-31
DE3382621D1 (de) 1992-10-15
DE3382621T2 (de) 1993-02-18
EP0300121A3 (en) 1990-09-26
JPH0751591B2 (ja) 1995-06-05
EP0099553B1 (de) 1989-09-27
EP0099553A3 (en) 1985-06-19
EP0300121B1 (de) 1992-09-09
JPH037296A (ja) 1991-01-14
JPH037292A (ja) 1991-01-14
US4563449A (en) 1986-01-07
JPH0448796B2 (de) 1992-08-07
EP0099553A2 (de) 1984-02-01
EP0300121A2 (de) 1989-01-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee