DE3368612D1 - Process for the production of guanidinoheterocyclic derivatives - Google Patents

Process for the production of guanidinoheterocyclic derivatives

Info

Publication number
DE3368612D1
DE3368612D1 DE8383304850T DE3368612T DE3368612D1 DE 3368612 D1 DE3368612 D1 DE 3368612D1 DE 8383304850 T DE8383304850 T DE 8383304850T DE 3368612 T DE3368612 T DE 3368612T DE 3368612 D1 DE3368612 D1 DE 3368612D1
Authority
DE
Germany
Prior art keywords
guanidinoheterocyclic
derivatives
production
appropriate
isourea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383304850T
Other languages
German (de)
English (en)
Inventor
Neil James Hales
Derrick Michael Mant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Application granted granted Critical
Publication of DE3368612D1 publication Critical patent/DE3368612D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/40—Acylated on said nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE8383304850T 1982-09-07 1983-08-23 Process for the production of guanidinoheterocyclic derivatives Expired DE3368612D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8225509 1982-09-07

Publications (1)

Publication Number Publication Date
DE3368612D1 true DE3368612D1 (en) 1987-02-05

Family

ID=10532749

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383304850T Expired DE3368612D1 (en) 1982-09-07 1983-08-23 Process for the production of guanidinoheterocyclic derivatives

Country Status (13)

Country Link
EP (1) EP0105590B1 (enExample)
JP (1) JPS59134781A (enExample)
AT (1) ATE24492T1 (enExample)
DD (1) DD216011A5 (enExample)
DE (1) DE3368612D1 (enExample)
DK (1) DK367783A (enExample)
ES (2) ES8507101A1 (enExample)
FI (1) FI833161L (enExample)
GB (1) GB8316779D0 (enExample)
GR (1) GR81302B (enExample)
NO (1) NO833179L (enExample)
PT (1) PT77263B (enExample)
SU (1) SU1303027A3 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8401751D0 (en) * 1984-01-24 1984-02-29 Ici Plc Guanidine derivatives
JP4746528B2 (ja) * 2006-12-06 2011-08-10 株式会社マスカワ ガスケット
JP2011099631A (ja) 2009-11-06 2011-05-19 Denso Corp 熱交換器
WO2012061698A2 (en) 2010-11-05 2012-05-10 Senomyx, Inc. Compounds useful as modulators of trpm8
WO2017058594A1 (en) 2015-10-01 2017-04-06 Senomyx, Inc. Compounds useful as modulators of trpm8

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1233818A (en) * 1981-03-09 1988-03-08 David J. Gilman Guanidine derivatives as histamine h-2 receptor antagonists
IN158869B (enExample) * 1981-03-18 1987-02-07 Ici Plc

Also Published As

Publication number Publication date
ES541830A0 (es) 1985-12-01
FI833161A7 (fi) 1984-03-08
GB8316779D0 (en) 1983-07-27
NO833179L (no) 1984-03-08
ES525445A0 (es) 1985-08-16
ES8602624A1 (es) 1985-12-01
FI833161L (fi) 1984-03-08
EP0105590B1 (en) 1986-12-30
DK367783A (da) 1984-03-08
PT77263A (en) 1983-09-01
PT77263B (en) 1986-02-04
JPS59134781A (ja) 1984-08-02
DD216011A5 (de) 1984-11-28
DK367783D0 (da) 1983-08-12
FI833161A0 (fi) 1983-09-05
SU1303027A3 (ru) 1987-04-07
GR81302B (enExample) 1984-12-11
EP0105590A1 (en) 1984-04-18
ES8507101A1 (es) 1985-08-16
ATE24492T1 (de) 1987-01-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee