DE3363960D1 - Bryozoan antibiotics - Google Patents

Bryozoan antibiotics

Info

Publication number
DE3363960D1
DE3363960D1 DE8383306896T DE3363960T DE3363960D1 DE 3363960 D1 DE3363960 D1 DE 3363960D1 DE 8383306896 T DE8383306896 T DE 8383306896T DE 3363960 T DE3363960 T DE 3363960T DE 3363960 D1 DE3363960 D1 DE 3363960D1
Authority
DE
Germany
Prior art keywords
bryozoan
antibiotics
bryozoan antibiotics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383306896T
Other languages
German (de)
English (en)
Inventor
George Robert Pettit
Cherry L Herald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Arizona
Arizona State University Downtown Phoenix campus
Original Assignee
University of Arizona
Arizona State University Downtown Phoenix campus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Arizona, Arizona State University Downtown Phoenix campus filed Critical University of Arizona
Application granted granted Critical
Publication of DE3363960D1 publication Critical patent/DE3363960D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8383306896T 1982-11-17 1983-11-11 Bryozoan antibiotics Expired DE3363960D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44248782A 1982-11-17 1982-11-17
US06/513,148 US4560774A (en) 1982-11-17 1983-07-12 Macrocyclic lactones

Publications (1)

Publication Number Publication Date
DE3363960D1 true DE3363960D1 (en) 1986-07-10

Family

ID=27033183

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383306896T Expired DE3363960D1 (en) 1982-11-17 1983-11-11 Bryozoan antibiotics

Country Status (4)

Country Link
US (1) US4560774A (cg-RX-API-DMAC7.html)
EP (1) EP0109811B1 (cg-RX-API-DMAC7.html)
JP (1) JPS59108786A (cg-RX-API-DMAC7.html)
DE (1) DE3363960D1 (cg-RX-API-DMAC7.html)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4611066A (en) * 1984-08-10 1986-09-09 Arizona State University Bryostatins 4 to 8
CA1291036C (en) * 1986-04-23 1991-10-22 Edwin I. Stoltz Nasal administration of drugs
US6043270A (en) * 1986-06-11 2000-03-28 Procyon Pharmaceuticals, Inc. Protein kinase C modulators V
IL82811A0 (en) * 1986-06-11 1987-12-20 Alder Res Center Corp Anti-inflammatory compositions containing methanol derivatives and novel compounds contained therein
US5716968A (en) * 1986-06-11 1998-02-10 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. H.
US5891906A (en) * 1986-06-11 1999-04-06 Procyon Pharmaceuticals, Inc. Polyacetate-derived phorboids having anti-inflammatory and other uses
US5891870A (en) * 1986-06-11 1999-04-06 Procyon Pharmaceuticals, Inc. Protein kinase C modulators Q
US5955501A (en) * 1986-06-11 1999-09-21 Procyon Pharmaceuticals, Inc. Protein kinase C modulators O
US4833257A (en) * 1986-07-28 1989-05-23 Arizona Board Of Regents Compositions of matter and methods of using same
US5358711A (en) * 1987-11-23 1994-10-25 Johns Hopkins University Stimulation of stem cell growth by the bryostatins
ATE97321T1 (de) * 1988-01-13 1993-12-15 Univ Arizona State Immunmodulierende bryostatine.
IT1229569B (it) * 1989-04-17 1991-09-04 Giuliani Spa Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
US5072004A (en) * 1990-12-31 1991-12-10 Arizona Board Of Regents Acting On Behalf Of Arizona State University Synthetic conversion of bryostatin 2 into bryostatin 1
US5196447A (en) * 1991-08-08 1993-03-23 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting On Behalf Of Arizona State University Neristatin 1
US5393897A (en) * 1993-07-02 1995-02-28 Arizona Board Of Regents Acting On Behalf Of Arizona State University Isolation and structure of spongistatins 5,7,8 and 9
US5684036A (en) * 1994-02-18 1997-11-04 Harbor Branch Oceanographic Institution, Inc. Cytotoxic macrolides and methods of use
US5478861A (en) * 1994-02-18 1995-12-26 Harbor Branch Oceanographic Institution, Inc. Cytotoxic macrolides and methods of use
US6060505A (en) * 1996-03-20 2000-05-09 The United States Of America As Represented By The Department Of Health And Human Services Method of treating cancer using C-26 modified bryostatin
BR9713661A (pt) 1996-12-30 2000-10-24 Battelle Memorial Institute Formulação e método para o tratamento de neoplasmas por inalação
AUPO864097A0 (en) 1997-08-19 1997-09-11 Peplin Pty Ltd Anti-cancer compounds
US6221153B1 (en) * 1998-06-09 2001-04-24 Trevor Percival Castor Method for producing large crystals of complex molecules
AU784589B2 (en) * 1999-11-30 2006-05-04 Board Of Trustees Of The Leland Stanford Junior University Bryostatin analogues, synthetic methods and uses
US7256286B2 (en) * 1999-11-30 2007-08-14 The Board Of Trustees Of The Leland Stanford Junior University Bryostatin analogues, synthetic methods and uses
AUPQ801700A0 (en) * 2000-06-07 2000-06-29 Peplin Research Pty Ltd Enzyme and viral activation
AUPQ923100A0 (en) 2000-08-07 2000-08-31 Peplin Research Pty Ltd Treatment of prostate cancer
AU2002256422A1 (en) * 2001-05-02 2002-11-11 Blanchette Rockefeller Neurosciences Institute Carbonic anhydrase activators for enhancing learning and memory
US6825229B2 (en) 2002-03-07 2004-11-30 Blanchette Rockefeller Neurosciences Institute Methods for Alzheimer's Disease treatment and cognitive enhancement
US20080004332A1 (en) * 2002-03-07 2008-01-03 Alkon Daniel L Methods for alzheimer's disease treatment and cognitive enhancement
US20050065205A1 (en) * 2002-03-07 2005-03-24 Daniel Alkon Methods for Alzheimer's disease treatment and cognitive enhance
TW201207390A (en) 2004-05-18 2012-02-16 Brni Neurosciences Inst Method for screening agent for antidepressant activity
NZ583157A (en) * 2004-12-13 2011-12-22 Leo Lab Ltd Treatment of solid cancers with angeloyl substituted ingenanes
JP5323481B2 (ja) 2005-07-29 2013-10-23 ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート 長期記憶を増強するための、ｐｋｃ賦活薬の単独またはｐｋｃ阻害剤と組み合わせての使用
NZ568168A (en) * 2005-11-25 2012-06-29 Leo Lab Ltd Methods for wound healing using ingenol compounds
JP2009544753A (ja) 2006-07-28 2009-12-17 ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート 細胞成長、シナプスリモデリング及び長期記憶の固定を刺激する方法
EP2121000B1 (en) * 2007-02-09 2015-09-23 Blanchette Rockefeller Neurosciences, Institute Therapeutic effects of bryostatins, bryologs, and other related substances on head trauma-induced memory impairment and brain injury
EP2121001B1 (en) 2007-02-09 2014-12-17 Blanchette Rockefeller Neurosciences, Institute Therapeutic effects of bryostatins on ischemia/stroke-induced memory impairment and brain injury
US9994585B2 (en) 2007-12-31 2018-06-12 Aphios Corporation Transplantation therapies
EP2590642B1 (en) 2010-07-08 2018-03-14 Daniel L. Alkon Pkc activators and anticoagulant in regimen for treating stroke
WO2012024630A1 (en) 2010-08-19 2012-02-23 Blanchette Rockefeller Neurosciences Institute Treatment of cognitive disorders associated with abnormal dendritic spines using pkc activators
EP2776018B1 (en) 2011-11-13 2021-08-25 Cognitive Research Enterprises, Inc. Pkc activators and combinations thereof
US9034347B2 (en) 2011-12-19 2015-05-19 Arphios Corporation Drug delivery system and method for the treatment of neuro-degenerative disease
US10828276B2 (en) 2012-11-28 2020-11-10 Aphios Corporation Combination therapeutics and methods for the treatment of neurodegenerative and other diseases
WO2016130969A1 (en) 2015-02-13 2016-08-18 George Robert Pettit Silstatin compounds
US20180217163A1 (en) 2015-05-11 2018-08-02 Daniel L. Alkon Treatment of neurodegenerative conditions using pkc activators after determining the presence of the apoe4 allele
JP7154539B2 (ja) 2016-08-18 2022-10-18 国立大学法人 奈良先端科学技術大学院大学 免疫調節剤
WO2018187647A1 (en) 2017-04-06 2018-10-11 Neurotrope Bioscience, Inc. Methods and compositions for treatment of neurological diseases, disorders, or conditions
WO2019094709A1 (en) 2017-11-09 2019-05-16 Pettit George R Betulastatin compounds
EP3793543A1 (en) 2018-05-18 2021-03-24 Neurotrope Bioscience, Inc. Methods and compositions for treatment of alzheimer's disease

Also Published As

Publication number Publication date
EP0109811A3 (en) 1984-07-11
EP0109811A2 (en) 1984-05-30
EP0109811B1 (en) 1986-06-04
US4560774A (en) 1985-12-24
JPS59108786A (ja) 1984-06-23
JPH0556357B2 (cg-RX-API-DMAC7.html) 1993-08-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition