DE3361211D1 - Glucosaminyl muramyl peptide derivatives - Google Patents

Glucosaminyl muramyl peptide derivatives

Info

Publication number
DE3361211D1
DE3361211D1 DE8383302714T DE3361211T DE3361211D1 DE 3361211 D1 DE3361211 D1 DE 3361211D1 DE 8383302714 T DE8383302714 T DE 8383302714T DE 3361211 T DE3361211 T DE 3361211T DE 3361211 D1 DE3361211 D1 DE 3361211D1
Authority
DE
Germany
Prior art keywords
peptide derivatives
muramyl peptide
glucosaminyl muramyl
glucosaminyl
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383302714T
Other languages
English (en)
Inventor
Yoshiyuki Takase
Ryuji Furuta
Shigeo Kawata
Shunsuke Naruto
Shinichi Nakamura
Akira Minami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dainippon Pharmaceutical Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd filed Critical Dainippon Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3361211D1 publication Critical patent/DE3361211D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8383302714T 1982-05-14 1983-05-13 Glucosaminyl muramyl peptide derivatives Expired DE3361211D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57082178A JPS58198496A (ja) 1982-05-14 1982-05-14 グルコサミニルムラミルペプチド誘導体

Publications (1)

Publication Number Publication Date
DE3361211D1 true DE3361211D1 (de) 1985-12-19

Family

ID=13767175

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383302714T Expired DE3361211D1 (de) 1982-05-14 1983-05-13 Glucosaminyl muramyl peptide derivatives

Country Status (4)

Country Link
US (1) US4545932A (de)
EP (1) EP0094804B1 (de)
JP (1) JPS58198496A (de)
DE (1) DE3361211D1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58126797A (ja) * 1982-01-22 1983-07-28 Dainippon Pharmaceut Co Ltd ジサツカライドトリペプチド及びジサツカライドテトラペプチドの製法
SI8611982A8 (en) * 1986-11-19 1995-04-30 Pliva Pharm & Chem Works Process for preparing complexes of N-acethyl-glucosisaminyl-N-acethyl- muramoil-L-alanyl-D-izoglutaminyl-(L)-mezodiaminopimelyl-(D-amid)- (L)-alanyl-D-alanine
US5416070A (en) * 1988-07-08 1995-05-16 Immunotherapeutics, Inc. Composition for macrophage activation
US4950645A (en) * 1988-07-08 1990-08-21 Immunotherapeutics, Inc. Composition for macrophage activation
YU62689A (en) * 1989-03-27 1991-02-28 Pliva Pharm & Chem Works N-acyl derivatives of peptidoglican monomer, their pharmaceutically acceptable salts, process for preparing thereof and their use as immunity modulators and immunoadjuvant
US5750665A (en) * 1995-10-04 1998-05-12 Vosika; Gerald J. Preparation of glucosaminyl muramic acid derivatives
US7112564B2 (en) * 2003-04-09 2006-09-26 Zylacta Corporation Biodegradable glucosaminemuramyl peptides for apoptosis modulation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
SU727647A1 (ru) * 1977-11-02 1980-04-15 Институт биоорганической химии им.М.М.Шемякина Гликопептиды,обладающие противоопухолевой активностью и способ их получени
US4391800A (en) * 1979-04-27 1983-07-05 Merck & Co., Inc. Immunologically active peptidyl disaccharides and methods of preparation

Also Published As

Publication number Publication date
EP0094804A1 (de) 1983-11-23
JPS58198496A (ja) 1983-11-18
JPH0321040B2 (de) 1991-03-20
US4545932A (en) 1985-10-08
EP0094804B1 (de) 1985-11-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee