DE3361093D1 - 1,4-dihydropyridine compound and a preparation method thereof - Google Patents

1,4-dihydropyridine compound and a preparation method thereof

Info

Publication number
DE3361093D1
DE3361093D1 DE8383101664T DE3361093T DE3361093D1 DE 3361093 D1 DE3361093 D1 DE 3361093D1 DE 8383101664 T DE8383101664 T DE 8383101664T DE 3361093 T DE3361093 T DE 3361093T DE 3361093 D1 DE3361093 D1 DE 3361093D1
Authority
DE
Germany
Prior art keywords
preparation
dihydropyridine compound
dihydropyridine
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383101664T
Other languages
German (de)
English (en)
Inventor
Yoichi Inoue
Toshio Matsumoto
Hirosuke Niwa
Kenichi Suzuki
Yasuo Hoshide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST ORGANICHESKOGO SINTEZA AK
Kowa Co Ltd
Original Assignee
INST ORGANICHESKOGO SINTEZA AK
Nikken Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST ORGANICHESKOGO SINTEZA AK, Nikken Chemicals Co Ltd filed Critical INST ORGANICHESKOGO SINTEZA AK
Application granted granted Critical
Publication of DE3361093D1 publication Critical patent/DE3361093D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE8383101664T 1982-02-23 1983-02-21 1,4-dihydropyridine compound and a preparation method thereof Expired DE3361093D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57026790A JPS58159490A (ja) 1982-02-23 1982-02-23 １，４−ジヒドロピリジン化合物

Publications (1)

Publication Number Publication Date
DE3361093D1 true DE3361093D1 (en) 1985-12-05

Family

ID=12203104

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383101664T Expired DE3361093D1 (en) 1982-02-23 1983-02-21 1,4-dihydropyridine compound and a preparation method thereof

Country Status (5)

Country Link
US (1) US4495356A (en, 2012)
EP (1) EP0087156B1 (en, 2012)
JP (1) JPS58159490A (en, 2012)
DE (1) DE3361093D1 (en, 2012)
ES (1) ES8403889A1 (en, 2012)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8601891A1 (es) * 1983-03-04 1985-11-01 Nikken Chemicals Co Ltd Un metodo para preparar compuestos de 1, 4-dihidropiridina
EP0149475B1 (en) * 1984-01-13 1990-04-18 Yamanouchi Pharmaceutical Co. Ltd. Medicaments for the treatment and prevention of liver damage
US4833150A (en) * 1985-03-14 1989-05-23 Nelson Research & Development Co. 1,4-dihydropyridines
US4849436A (en) * 1986-03-11 1989-07-18 Nelson Research & Development Co. 1,4-dihydropyridines
US4985558A (en) * 1988-07-28 1991-01-15 Nikken Chemicals Co., Ltd. 1,4-dihydropyridine derivative
GB9119983D0 (en) * 1991-09-19 1991-11-06 Erba Carlo Spa Dihydropyridine derivatives useful in antitumor therapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511847A (en) * 1967-02-07 1970-05-12 Smithkline Corp 2,6-di-lower alkyl - 1,4-dihydro - 4-(2-trifluoromethylphenyl) - 3,5 - pyridinedicarboxylic acid esters
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
DE1813436C3 (de) * 1968-12-07 1979-01-11 Bayer Ag, 5090 Leverkusen N-Substituierte 2,6-Dimethyl-l,4dihydropyridine
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
DE2117573C3 (de) * 1971-04-10 1978-07-27 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2218644C3 (de) * 1972-04-18 1982-08-19 Bayer Ag, 5090 Leverkusen Basische Ester von 1,4-Dihydropyridinen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2349538C2 (de) * 1973-10-02 1982-08-26 Ordena trudovogo krasnogo znameni institut organičeskogo sinteza Akademii Nauk Latvijskoj SSR, Riga Arzneimittel zur Behandlung von Lebererkrankungen
DE3022030A1 (de) * 1980-06-12 1981-12-17 Bayer Ag, 5090 Leverkusen 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel

Also Published As

Publication number Publication date
EP0087156B1 (en) 1985-10-30
ES519990A0 (es) 1984-04-01
JPH0129794B2 (en, 2012) 1989-06-14
JPS58159490A (ja) 1983-09-21
ES8403889A1 (es) 1984-04-01
EP0087156A1 (en) 1983-08-31
US4495356A (en) 1985-01-22

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Free format text: KADOR, U., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 8000 MUENCHEN

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee