DE3269846D1 - Novel steroid saponins, process for their extraction, and process for preparing 16-dehydropregnenolone therefrom - Google Patents
Novel steroid saponins, process for their extraction, and process for preparing 16-dehydropregnenolone therefromInfo
- Publication number
- DE3269846D1 DE3269846D1 DE8282902830T DE3269846T DE3269846D1 DE 3269846 D1 DE3269846 D1 DE 3269846D1 DE 8282902830 T DE8282902830 T DE 8282902830T DE 3269846 T DE3269846 T DE 3269846T DE 3269846 D1 DE3269846 D1 DE 3269846D1
- Authority
- DE
- Germany
- Prior art keywords
- dehydropregnenolone
- therefrom
- extraction
- preparing
- steroid saponins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YLFRRPUBVUAHSR-RRPFGEQOSA-N 16,17-didehydropregnenolone Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC=C(C(=O)C)[C@@]1(C)CC2 YLFRRPUBVUAHSR-RRPFGEQOSA-N 0.000 title 1
- YLFRRPUBVUAHSR-UHFFFAOYSA-N 16-dehydro-pregnenolone Natural products C1C=C2CC(O)CCC2(C)C2C1C1CC=C(C(=O)C)C1(C)CC2 YLFRRPUBVUAHSR-UHFFFAOYSA-N 0.000 title 1
- 238000000605 extraction Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000005856 steroid saponins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56152488A JPS5855500A (ja) | 1981-09-25 | 1981-09-25 | 16−デヒドロプレグネノロンの製造法 |
| PCT/JP1982/000384 WO1983001065A1 (fr) | 1981-09-25 | 1982-09-24 | Nouvelles saponines steroides, leur procede d'extraction, et procede de preparation de 16-dehydropregnenolone a partir de ces nouvelles saponines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3269846D1 true DE3269846D1 (en) | 1986-04-17 |
Family
ID=15541570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8282902830T Expired DE3269846D1 (en) | 1981-09-25 | 1982-09-24 | Novel steroid saponins, process for their extraction, and process for preparing 16-dehydropregnenolone therefrom |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4482706A (enExample) |
| EP (1) | EP0089377B1 (enExample) |
| JP (1) | JPS5855500A (enExample) |
| DE (1) | DE3269846D1 (enExample) |
| WO (1) | WO1983001065A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5862200A (ja) * | 1981-10-07 | 1983-04-13 | Tokiwa Yakuhin Kogyo Kk | 16−デヒドロプレグノロンの製造法 |
| JP2562134B2 (ja) * | 1986-09-19 | 1996-12-11 | 喜徳 喜谷 | 新規な白金−ステロイド錯体 |
| US5808117A (en) * | 1996-01-22 | 1998-09-15 | Chowdhury; Pritish Kumar | Process for the production of 16-Dehydropregenolone acetate form diosgenin |
| GB9923076D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| KR20070007214A (ko) * | 1998-03-26 | 2007-01-12 | 파이토팜 피엘씨 | 알츠하이머병을 치료하기 위한 스밀라게닌 및안주로게닌-d |
| GB9923078D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| GB9923077D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| GB0000228D0 (en) * | 2000-01-06 | 2000-03-01 | Phytopharm Plc | Fluoro substituted sapogenins and their use |
| GB0107822D0 (en) * | 2001-03-28 | 2001-05-23 | Phytopharm Plc | Sapogenin derivatives their synthesis and use methods based upon their use |
| US20050130948A1 (en) * | 2002-03-27 | 2005-06-16 | Daryl Rees | Therapeutic methods and uses of sapogenins and their derivatives |
| CN102727501A (zh) * | 2002-03-27 | 2012-10-17 | 菲特法姆股份有限公司 | 皂角苷配基及其衍生物的用途 |
| JP2010535758A (ja) * | 2008-01-04 | 2010-11-25 | ビオスペクトルム,インコーポレイテッド | ジオスゲニンを含む皮膚美白用組成物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3294785A (en) * | 1963-07-29 | 1966-12-27 | Schering Corp | Novel process for the conversion of a sapogenin to a 16-dehydro steroid and intermediates produced thereby |
| GB1503388A (en) * | 1975-07-01 | 1978-03-08 | Inverni Della Beffa Spa | Pharmaceutically active complexes and pharmaceutical compositions containing them |
| GB2019407B (en) * | 1978-04-14 | 1982-10-06 | Yamasa Shoyu Kk | Glycosides of compounds of the 3-hydroxy oleanane series and their extraction from plants of genus periandra |
| DE2926463A1 (de) * | 1978-07-05 | 1980-01-24 | Roecar Holdings Nv | Spiroketaline und ihre verwendung |
| JPS5943960B2 (ja) * | 1979-10-29 | 1984-10-25 | 株式会社大阪薬品研究所 | 新規サポニン物質 |
-
1981
- 1981-09-25 JP JP56152488A patent/JPS5855500A/ja active Granted
-
1982
- 1982-09-24 US US06/491,964 patent/US4482706A/en not_active Expired - Fee Related
- 1982-09-24 DE DE8282902830T patent/DE3269846D1/de not_active Expired
- 1982-09-24 EP EP82902830A patent/EP0089377B1/en not_active Expired
- 1982-09-24 WO PCT/JP1982/000384 patent/WO1983001065A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0089377A4 (en) | 1984-11-23 |
| JPS5855500A (ja) | 1983-04-01 |
| EP0089377A1 (en) | 1983-09-28 |
| WO1983001065A1 (fr) | 1983-03-31 |
| JPS6310160B2 (enExample) | 1988-03-04 |
| EP0089377B1 (en) | 1986-03-12 |
| US4482706A (en) | 1984-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |