DE3172980D1 - Novel polycyclic indole derivatives - Google Patents

Novel polycyclic indole derivatives

Info

Publication number
DE3172980D1
DE3172980D1 DE8181303411T DE3172980T DE3172980D1 DE 3172980 D1 DE3172980 D1 DE 3172980D1 DE 8181303411 T DE8181303411 T DE 8181303411T DE 3172980 T DE3172980 T DE 3172980T DE 3172980 D1 DE3172980 D1 DE 3172980D1
Authority
DE
Germany
Prior art keywords
indole derivatives
group
novel polycyclic
chem
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181303411T
Other languages
German (de)
English (en)
Inventor
Keiichi Ono
Hajime Kawakami
Junki Katsube
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Application granted granted Critical
Publication of DE3172980D1 publication Critical patent/DE3172980D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
DE8181303411T 1980-08-06 1981-07-24 Novel polycyclic indole derivatives Expired DE3172980D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10849580A JPS5732281A (en) 1980-08-06 1980-08-06 Nitrogen-containing polycyclic compound and its preparation

Publications (1)

Publication Number Publication Date
DE3172980D1 true DE3172980D1 (de) 1986-01-02

Family

ID=14486216

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181303411T Expired DE3172980D1 (de) 1980-08-06 1981-07-24 Novel polycyclic indole derivatives

Country Status (7)

Country Link
US (1) US4366157A (enExample)
EP (1) EP0045602B1 (enExample)
JP (1) JPS5732281A (enExample)
AT (1) ATE16593T1 (enExample)
DE (1) DE3172980D1 (enExample)
ES (1) ES504273A0 (enExample)
HU (1) HU185303B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522894A1 (de) * 1985-06-24 1987-01-02 Schering Ag Verwendung von tergurid als geriatrikum
US4665183A (en) * 1985-12-20 1987-05-12 American Home Products Corp. Process for preparing 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof useful for the treatment of cognitive impairments
US4624954A (en) * 1985-12-20 1986-11-25 American Home Products Corporation 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof, useful for the treatment of cognitive impairments
FR2713644B1 (fr) * 1993-12-14 1996-02-09 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
WO2009029206A1 (en) * 2007-08-24 2009-03-05 Wake Forest University Health Sciences Chemotherapeutic for inducing an msh2-dependent apoptotic pathway

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1445500A1 (de) * 1963-06-07 1968-12-05 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer Yohimban-Derivate und deren Salze
US3318877A (en) * 1964-12-23 1967-05-09 Ciba Geigy Corp 16, 17, 18-triepi-deserpidates
US3492304A (en) * 1968-06-24 1970-01-27 Warner Lambert Pharmaceutical 5,6,7,7a,8,8a,9,10,12,12a-decahydro-11h-benz(b)indolo(3,2,1-ij) 1,5 naphthyridin-11-ones
US3702325A (en) * 1969-08-07 1972-11-07 Lab Toraude Indole alkaloid derivatives
AT325786B (de) 1972-05-17 1975-11-10 Richter Gedeon Vegyeszet Verfahren zur herstellung von eburnamoninen
GB1426609A (en) * 1973-08-02 1976-03-03 Serdex Soc Detudes De Rech De Reserpic acid derivatives process for their preparation and apllications thereof
FR2255885B1 (enExample) * 1973-12-28 1977-09-09 Centre Etd Ind Pharma
DE2538095A1 (de) * 1974-09-06 1976-03-25 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
HU171663B (hu) * 1975-09-01 1978-02-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 14-skobka-zamehhennogo metil-skobka zakryta-vinkana
AU532001B2 (en) * 1978-11-20 1983-09-15 Sumitomo Chemical Company, Limited Polycyclic indole derivatives
US4316028A (en) * 1978-11-20 1982-02-16 Sumitomo Chemical Company, Limited Process for producing eburnane derivatives

Also Published As

Publication number Publication date
EP0045602A1 (en) 1982-02-10
ES8301478A1 (es) 1982-12-01
ES504273A0 (es) 1982-12-01
ATE16593T1 (de) 1985-12-15
JPS5732281A (en) 1982-02-20
EP0045602B1 (en) 1985-11-21
JPS6258358B2 (enExample) 1987-12-05
HU185303B (en) 1985-01-28
US4366157A (en) 1982-12-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee