DE3165782D1 - 5-fluoro uracil derivatives - Google Patents

5-fluoro uracil derivatives

Info

Publication number
DE3165782D1
DE3165782D1 DE8181304464T DE3165782T DE3165782D1 DE 3165782 D1 DE3165782 D1 DE 3165782D1 DE 8181304464 T DE8181304464 T DE 8181304464T DE 3165782 T DE3165782 T DE 3165782T DE 3165782 D1 DE3165782 D1 DE 3165782D1
Authority
DE
Germany
Prior art keywords
uracil derivatives
fluoro uracil
fluoro
derivatives
uracil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181304464T
Other languages
English (en)
Inventor
Michael Raymond Harnden
Stuart Bailey
Colin Thomas Shanks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE3165782D1 publication Critical patent/DE3165782D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/12—Saturated ethers containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/303—Compounds having groups having acetal carbon atoms bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8181304464T 1980-10-01 1981-09-28 5-fluoro uracil derivatives Expired DE3165782D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8031721 1980-10-01
GB8123032 1981-07-25

Publications (1)

Publication Number Publication Date
DE3165782D1 true DE3165782D1 (en) 1984-10-04

Family

ID=26277075

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181304464T Expired DE3165782D1 (en) 1980-10-01 1981-09-28 5-fluoro uracil derivatives

Country Status (3)

Country Link
EP (1) EP0049144B1 (de)
DE (1) DE3165782D1 (de)
GB (1) GB2085002B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2022024A6 (es) * 1990-05-07 1991-11-16 Univ Granada Sintesis de nuevos derivados de uracilo con actividad antitumoral y compuestos referibles (n-1-derivados de uracilos-5- sustituidos)
JP7116294B2 (ja) * 2017-03-10 2022-08-10 ダイキン工業株式会社 環状カーボネート化合物、及びその製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1393863A (en) * 1973-06-21 1975-05-14 I Orch Sinteza Akademii Nauk L Process for producing n1-dihydroxyalkyl uracils
US4124765A (en) * 1975-05-13 1978-11-07 Ono Pharmaceutical Co., Ltd. 5-Fluorouracil derivatives
JPS6024789B2 (ja) * 1976-09-03 1985-06-14 小野薬品工業株式会社 ５−フルオロウラシル誘導体化合物

Also Published As

Publication number Publication date
GB2085002B (en) 1984-08-08
GB2085002A (en) 1982-04-21
EP0049144A1 (de) 1982-04-07
EP0049144B1 (de) 1984-08-29

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee