DE3071977D1 - Peptides, process for their preparation, their pharmaceutical compositions and their intermediates - Google Patents

Peptides, process for their preparation, their pharmaceutical compositions and their intermediates

Info

Publication number
DE3071977D1
DE3071977D1 DE8080104502T DE3071977T DE3071977D1 DE 3071977 D1 DE3071977 D1 DE 3071977D1 DE 8080104502 T DE8080104502 T DE 8080104502T DE 3071977 T DE3071977 T DE 3071977T DE 3071977 D1 DE3071977 D1 DE 3071977D1
Authority
DE
Germany
Prior art keywords
intermediates
peptides
preparation
pharmaceutical compositions
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080104502T
Other languages
English (en)
Inventor
Yoshihiko Kitaura
Osamu Nakaguchi
Keiji Hemmi
Matsuhiko Aratani
Hidekazu Takeno
Satoshi Okada
Hirokazu Tanaka
Masashi Hashimoto
Yoshio Kuroda
Eiko Iguchi
Masanobu Kohsaka
Hatsuo Aoki
Hiroshi Imanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/093,523 external-priority patent/US4311640A/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3071977D1 publication Critical patent/DE3071977D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE8080104502T 1979-07-31 1980-07-30 Peptides, process for their preparation, their pharmaceutical compositions and their intermediates Expired DE3071977D1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB7926705 1979-07-31
GB7935401 1979-10-11
GB7935730 1979-10-15
GB7936000 1979-10-17
GB7937343 1979-10-29
US06/093,523 US4311640A (en) 1978-11-14 1979-11-13 Peptide, process for preparation thereof and use thereof
US11002080A 1980-01-07 1980-01-07
US14771080A 1980-05-08 1980-05-08
US14944180A 1980-05-13 1980-05-13

Publications (1)

Publication Number Publication Date
DE3071977D1 true DE3071977D1 (en) 1987-07-09

Family

ID=27576280

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080104502T Expired DE3071977D1 (en) 1979-07-31 1980-07-30 Peptides, process for their preparation, their pharmaceutical compositions and their intermediates

Country Status (8)

Country Link
EP (1) EP0025842B1 (de)
JP (2) JPS63258488A (de)
AU (1) AU544864B2 (de)
DE (1) DE3071977D1 (de)
DK (1) DK156252C (de)
GR (1) GR65931B (de)
HU (1) HU188565B (de)
MX (1) MX5971E (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749691A (en) * 1978-11-14 1988-06-07 Fujisawa Pharmaceutical Co., Ltd. Peptide, process for preparation thereof and use thereof
US4801580A (en) * 1978-11-14 1989-01-31 Fujisawa Pharmaceutical Company, Ltd. Peptide, process for preparation thereof and use thereof
US4725582A (en) * 1978-11-14 1988-02-16 Fujisawa Pharmaceutical Company, Ltd. Peptide, process for preparation thereof and use thereof
US4539155A (en) * 1978-11-14 1985-09-03 Fuisawa Pharmaceutical Company, Ltd. New peptide, process for preparation thereof and use thereof
US4458078A (en) * 1978-11-14 1984-07-03 Fujisawa Pharmaceutical Company, Ltd. Oxazole derivatives
IE51684B1 (en) * 1980-10-27 1987-02-04 Fujisawa Pharmaceutical Co Peptides,process for their preparation and pharmaceutical compositions containing them
GR81332B (de) * 1980-12-01 1984-12-11 Fujisawa Pharmaceutical Co
US4565653A (en) * 1984-03-30 1986-01-21 Pfizer Inc. Acyltripeptide immunostimulants
ATE46347T1 (de) * 1985-11-25 1989-09-15 Pfizer Immunostimulierende peptide.
FR2635779A2 (fr) * 1987-02-26 1990-03-02 Roussel Uclaf Nouveaux derives de l'acide glutamique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2611721B1 (fr) * 1987-02-26 1990-01-26 Roussel Uclaf Nouveaux derives de l'acide glutamique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
US4938956A (en) * 1987-04-01 1990-07-03 International Minerals & Chemical Corp. Synergistic immunostimulating composition and method
GB8806429D0 (en) * 1988-03-18 1988-04-20 Fujisawa Pharmaceutical Co Fr-900493 substance process for production & pharmaceutical composition containing same
FR2684674B1 (fr) * 1991-12-10 1994-01-28 Thevac Sarl Azapeptides et leur procede de preparation.
JP3001173U (ja) * 1994-02-18 1994-08-23 有限会社野々川商事 染毛用ブラシ
AUPO161196A0 (en) * 1996-08-13 1996-09-05 Commonwealth Scientific And Industrial Research Organisation Novel compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2292486A1 (fr) * 1974-07-01 1976-06-25 Anvar Adjuvants immunologiques solubles dans l'eau, notamment pour vaccins, obtenus a partir de microbacteries et autres micro-organismes
FR2248025A2 (en) * 1973-10-23 1975-05-16 Anvar Vaccine compsns. - contg. N-acyl muramic acid deriv. as adjuvant
FR2324311A1 (fr) * 1975-09-17 1977-04-15 Anvar Adjuvants immunologiques solubles dans l'eau, notamment pour vaccins, obtenus a partir de mycobacteries et autres micro-organismes
FR2343484A1 (fr) * 1976-03-10 1977-10-07 Anvar Le 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d- (a-methylamide)-glutamique et medicaments le contenant
JPS52151731A (en) * 1976-06-14 1977-12-16 Kyowa Hakko Kogyo Co Ltd Tumor-inhibitory composition
JPS52151732A (en) * 1976-06-14 1977-12-16 Kyowa Hakko Kogyo Co Ltd Prophylactic and therapeutic agent against bacterial
FI66878C (fi) * 1978-02-24 1984-12-10 Ciba Geigy Ag Foerfarande foer framstaellning av nya antigenderivat
JPS54130516A (en) * 1978-03-31 1979-10-09 Yuuichi Yamamura Acyllnnacetylmuramylpeptide derivativeeantigen combination
GB2033906B (en) * 1978-10-19 1982-12-01 Anvar Water-soluble compounds derived from extracts of streptomyces stimulosus process for their production and compositions containing them
FR2460290A1 (fr) * 1979-06-29 1981-01-23 Rhone Poulenc Ind Nouveaux tetra- ou pentapeptides, leur preparation et les medicaments qui les contiennent
FR2460289A1 (fr) * 1979-06-29 1981-01-23 Rhone Poulenc Ind Nouveaux tripeptides, leur preparation et les medicaments qui les contiennent

Also Published As

Publication number Publication date
EP0025842B1 (de) 1987-06-03
DK156252C (da) 1989-12-18
AU6093980A (en) 1981-03-19
JPH0613549B2 (ja) 1994-02-23
DK156252B (da) 1989-07-17
JPH0327560B2 (de) 1991-04-16
JPH02288895A (ja) 1990-11-28
MX5971E (es) 1984-09-10
EP0025842A3 (en) 1982-02-10
HU188565B (en) 1986-04-28
JPS63258488A (ja) 1988-10-25
GR65931B (de) 1980-12-16
AU544864B2 (en) 1985-06-20
EP0025842A2 (de) 1981-04-01
DK327280A (da) 1981-02-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee