DE3069243D1 - 2-(4-piperidyl)-1-(4-quinolyl)-ethanone derivatives, intermediates in and process for their preparation, and their use as medicines - Google Patents

2-(4-piperidyl)-1-(4-quinolyl)-ethanone derivatives, intermediates in and process for their preparation, and their use as medicines

Info

Publication number
DE3069243D1
DE3069243D1 DE8080401788T DE3069243T DE3069243D1 DE 3069243 D1 DE3069243 D1 DE 3069243D1 DE 8080401788 T DE8080401788 T DE 8080401788T DE 3069243 T DE3069243 T DE 3069243T DE 3069243 D1 DE3069243 D1 DE 3069243D1
Authority
DE
Germany
Prior art keywords
piperidyl
quinolyl
medicines
intermediates
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080401788T
Other languages
English (en)
Inventor
Alain Andre Champseix
Fur Gerard Roger Le
Christian Louis Albert Renault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmuka Laboratoires SA
Original Assignee
Pharmuka Laboratoires SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmuka Laboratoires SA filed Critical Pharmuka Laboratoires SA
Application granted granted Critical
Publication of DE3069243D1 publication Critical patent/DE3069243D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8080401788T 1979-12-21 1980-12-12 2-(4-piperidyl)-1-(4-quinolyl)-ethanone derivatives, intermediates in and process for their preparation, and their use as medicines Expired DE3069243D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7931396A FR2471981A1 (fr) 1979-12-21 1979-12-21 Nouveaux derives de la (piperidyl-4)-2 (quinolyl-4)-1 ethanone, produits intermediaires et procedes pour leur preparation, et leur utilisation comme medicaments

Publications (1)

Publication Number Publication Date
DE3069243D1 true DE3069243D1 (en) 1984-10-25

Family

ID=9233056

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080401788T Expired DE3069243D1 (en) 1979-12-21 1980-12-12 2-(4-piperidyl)-1-(4-quinolyl)-ethanone derivatives, intermediates in and process for their preparation, and their use as medicines

Country Status (12)

Country Link
US (2) US4433150A (de)
EP (1) EP0031753B1 (de)
JP (1) JPS5699476A (de)
AT (1) AT376670B (de)
CA (1) CA1178589A (de)
DE (1) DE3069243D1 (de)
DK (1) DK530480A (de)
ES (3) ES498017A0 (de)
FR (1) FR2471981A1 (de)
IE (1) IE51124B1 (de)
NO (1) NO155137C (de)
PT (1) PT72212A (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908031A (nl) * 1979-11-01 1981-06-01 Acf Chemiefarma Nv Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
US4442107A (en) * 1980-03-06 1984-04-10 Acf Chemiefarma N.V. Quinoline derivatives, pharmaceutical compositions containing such compounds, and methods for treating cardiovascular conditions with them
FR2495470A1 (fr) * 1980-12-05 1982-06-11 Pharmindustrie Nouveaux medicaments a base de derives de (quinolyl-4)-1 (piperidyl-4)-2 ethanol ou (quinolyl-4)-1 (piperidyl-4)-3 propanol
FR2582514B1 (fr) * 1985-05-30 1988-02-19 Rhone Poulenc Sante Medicaments a base d'amides, nouveaux amides et leur preparation
WO1999043681A1 (en) 1998-02-26 1999-09-02 Neurogen Corporation 4-(4-piperidylmethylamino) substituted heteroaryl fused pyridines: gaba brain receptor ligands
GB9917406D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917408D0 (en) * 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
US6693099B2 (en) * 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US6376514B1 (en) * 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
AR037641A1 (es) * 2001-12-05 2004-11-17 Tularik Inc Moduladores de inflamacion
WO2003064421A1 (en) 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine derivatives
US7348434B2 (en) 2003-08-08 2008-03-25 Antony Bigot 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
FR2858619B1 (fr) * 2003-08-08 2006-12-22 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
EP2481735A1 (de) * 2007-05-09 2012-08-01 Pfizer Inc. Substituierte heterocyclische Derivate und Zusammensetzungen und ihre pharmazeutische Verwendung als antibakterielle Mittel

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR31753E (fr) * 1925-12-03 1927-06-11 Appareil photographique pour prise de vues, agrandissement et projection
FR42781E (fr) * 1932-05-23 1933-10-10 Perfectionnements aux machines rotatives à capsuler les bouteilles
FR959917A (de) * 1946-06-25 1950-04-07
FR2177511A1 (en) * 1972-03-28 1973-11-09 Omnium Chimique Sa Quinolyl pipiridylethyl ketones - with vasodilatory and antispasmodic activity
PT66682B (pt) * 1976-06-18 1978-11-15 Ind Biolog Francaise /(quinolyl-4)-propyl-1/-4 piperidines leur preparation et leur utilisation comme medicaments /(quinolyl-4)-propyl/-4 piperidines leur preparation et leur utilisation comme medicaments
FR2354771A1 (fr) * 1976-06-18 1978-01-13 Mar Pha Etu Expl Marques ((quinolyl-4)-3 propyl-1) -4 piperidines, leur preparation et leur utilisation comme medicaments
FR2485014A1 (fr) * 1980-06-20 1981-12-24 Pharmindustrie Nouveaux derives de (quinolyl-2, -3 ou -4)-1 (piperidyl ou pyrrolidinyl-2 ou -3)-2 ou -3 ethanone ou propanone, procedes pour leur preparation, et leur utilisation comme medicaments

Also Published As

Publication number Publication date
ES507998A0 (es) 1982-10-01
IE51124B1 (en) 1986-10-15
NO803881L (no) 1981-06-22
FR2471981A1 (fr) 1981-06-26
PT72212A (pt) 1981-01-01
CA1178589A (fr) 1984-11-27
ES8300745A1 (es) 1982-11-01
IE802684L (en) 1981-06-21
NO155137B (no) 1986-11-10
ES507997A0 (es) 1982-10-01
EP0031753A1 (de) 1981-07-08
DK530480A (da) 1981-06-22
ES8207525A1 (es) 1982-10-01
EP0031753B1 (de) 1984-09-19
NO155137C (no) 1987-02-18
ATA609680A (de) 1984-05-15
ES8207526A1 (es) 1982-10-01
US4505916A (en) 1985-03-19
JPS5699476A (en) 1981-08-10
AT376670B (de) 1984-12-27
ES498017A0 (es) 1982-11-01
US4433150A (en) 1984-02-21
FR2471981B1 (de) 1983-03-25

Similar Documents

Publication Publication Date Title
YU76879A (en) Process for preparing 11-aza-4-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-10-one and derivatives thereof
EP0412848A3 (en) Quinoline derivatives, process for their preparation and their use as medicaments
ZA803096B (en) Phenylsulphonamide derivatives, a process for their preparation and their use as medicines
DE3069243D1 (en) 2-(4-piperidyl)-1-(4-quinolyl)-ethanone derivatives, intermediates in and process for their preparation, and their use as medicines
DE3060427D1 (en) 2-substituted 5-phenoxy-phenylphosphonic acid derivatives, process for preparing them and their use as herbicides
HU182185B (en) Process for preparing 5-substituted 2,3-diaryl-thiophene derivatives
DE3275185D1 (en) Mandelic acid derivatives, process for their preparation and their microbicidal application
DE3169169D1 (en) 1-(4 quinolyl), 2- or 3- (2- or 3- piperidyl or pyrrolidinyl) ethanone or propanone, process for their preparation and their use as medicaments
EP0012643A3 (en) 1-phenyl-3-(4-piperidyl)-propan-1-one derivatives, processes for and intermediates in their preparation, and medicaments containing them
EP0033655A3 (en) Imidazoline derivative, its salts, process for preparation, pharmaceutical compositions and therapeutic use, thereof
HU184064B (en) Process for preparing new 2,3,5-trichloropyridine and 2,4,4-tri-chloro-4-formyl-butyronitrile derivatives
DE3062884D1 (en) Spiro-hydantoin derivatives, process for their preparation and pharmaceutical compositions thereof
DE3069789D1 (en) Substituted heterocyclic phenoxy amines, their preparation method and their use as local anaesthetics
DE2965259D1 (en) Heterocycle substituted (3-loweralkylamino-2-ro-propoxy)pyridines, process for preparing the same,and pharmaceutical composition containing the same
DE3169602D1 (en) 2-pyridinecarboxamide derivative, process for preparing same and pharmaceutical composition, useful as an anti-allergic agent
DE2860981D1 (en) 4-hydroxy-2-benzimidazolinone derivatives, process for their preparation and their use in medicaments
EP0029542A3 (en) Hydroxybutyl-imidazole derivatives, process for their preparation and their use as fungicides
ZA802673B (en) Novel derivatives of 5h-furanone-2 and of 3h-dihydrofuranone-2, the process for preparing the same and their application in therapeutics
IL59719A (en) 2-(pyrid-2-yl)tetrahydrothiophene derivatives,process for their preparation and pharmaceutical compositions comprising the same
DE2960167D1 (en) 1.1-diphenylethene derivatives, process for their preparation and their use as microbicides
ZA793336B (en) Novel phenylpiperidine derivatives,processes for their preparation,pharmaceutical preparations containing these derivatives and their use
LU79601A1 (fr) Procede de preparation de nouveaux derives de 1h-1,2,4-triazoles disubstitues dans les positions 3,5
ZA803879B (en) Heterocyclic compounds, processes for their preparation and their use
DE2961524D1 (en) Glycofuranosyl-nitrosourea derivatives, process for their manufacture and their pharmaceutical preparations
DE3267658D1 (en) 1-(3-(6-fluoro-1,2-benzisoxasol-3-yl)propyl)-4-hydroxy-4-phenylpiperidines, a process for their preparation and their use as medicaments

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee