DE3068986D1 - Ophthalmic inserts for lowering intraocular pressure comprising carbonic anhydrase inhibitors - Google Patents
Ophthalmic inserts for lowering intraocular pressure comprising carbonic anhydrase inhibitorsInfo
- Publication number
- DE3068986D1 DE3068986D1 DE8080400129T DE3068986T DE3068986D1 DE 3068986 D1 DE3068986 D1 DE 3068986D1 DE 8080400129 T DE8080400129 T DE 8080400129T DE 3068986 T DE3068986 T DE 3068986T DE 3068986 D1 DE3068986 D1 DE 3068986D1
- Authority
- DE
- Germany
- Prior art keywords
- intraocular pressure
- carbonic anhydrase
- anhydrase inhibitors
- lowering intraocular
- ophthalmic inserts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP80400129A EP0033042B1 (de) | 1980-01-28 | 1980-01-28 | Ophthalmische kohlensaure Anhydrase-Inhibitoren enthaltende Einlagen zur Verringerung intraokularer Hypertension |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3068986D1 true DE3068986D1 (en) | 1984-09-27 |
Family
ID=8187357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8080400129T Expired DE3068986D1 (en) | 1980-01-28 | 1980-01-28 | Ophthalmic inserts for lowering intraocular pressure comprising carbonic anhydrase inhibitors |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0033042B1 (de) |
AT (1) | ATE9059T1 (de) |
DE (1) | DE3068986D1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE50901B1 (en) * | 1980-03-04 | 1986-08-06 | Merck & Co Inc | Ophthalmic compositions of carbonic anhydrase inhibitors for topical application in the treatment of elevated intraocular pressure |
GB2155331B (en) * | 1980-07-09 | 1988-09-01 | Florida University Of | Composition for reducing intraocular pressure |
US4386098A (en) * | 1981-11-03 | 1983-05-31 | Merck & Co., Inc. | 6-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure |
GB8623661D0 (en) * | 1986-10-02 | 1986-11-05 | Darougar S | Ocular insert |
US4824866A (en) * | 1987-02-02 | 1989-04-25 | Riker Laboratories, Inc. | Anti-glaucoma use of trifluoromethanesulfonamide |
GB2203039B (en) * | 1987-03-02 | 1990-10-24 | American Cyanamid Co | Stable ophthalmic preparations containing acetazolamide |
IT1223150B (it) * | 1987-11-18 | 1990-09-12 | Ubaldo Conte | Compressa per uso oftalmico e rilascio controllato della sostanza attiva |
US5466233A (en) * | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
CA2294343A1 (en) * | 1997-06-26 | 1999-01-07 | Merck & Co., Inc. | Method for optimizing retinal and optic nerve health |
US6264971B1 (en) | 1999-11-04 | 2001-07-24 | Btg International Limited | Ocular insert |
EP1404297B1 (de) | 2001-06-12 | 2011-04-27 | The Johns Hopkins University School Of Medicine | Reservoirvorrichtung für die intraokulare arzneimittelabgabe |
AU2002325220A1 (en) * | 2002-05-24 | 2003-12-12 | Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh | Drop-forming ophthalmic gel preparation comprising diclofenamide and timolol |
US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
PL2391419T3 (pl) | 2009-01-29 | 2019-12-31 | Forsight Vision4, Inc. | Dostarczanie leku do tylnego odcinka |
US8469934B2 (en) | 2010-01-27 | 2013-06-25 | Alcon Research, Ltd. | Pulsatile peri-corneal drug delivery device |
US10166142B2 (en) | 2010-01-29 | 2019-01-01 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
SI2600812T1 (sl) | 2010-08-05 | 2021-12-31 | ForSight Vision4, Inc., | Naprava za zdravljenje očesa |
WO2012019139A1 (en) | 2010-08-05 | 2012-02-09 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
EP3861969A1 (de) | 2010-08-05 | 2021-08-11 | ForSight Vision4, Inc. | Injektorvorrichtung zur arzneimittelabgabe |
CA2818612C (en) | 2010-11-19 | 2020-12-29 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
EP4249059A3 (de) | 2011-06-28 | 2023-11-29 | ForSight Vision4, Inc. | Vorrichtung zum sammeln einer flüssigkeitsprobe aus einer reservoirkammer einer therapeutischen vorrichtung für das auge |
SI2755600T1 (sl) | 2011-09-16 | 2021-08-31 | Forsight Vision4, Inc. | Naprava za izmenjavo tekočine |
CN103110575B (zh) * | 2013-03-07 | 2014-11-05 | 宁夏康亚药业有限公司 | 一种美洛昔康滴眼液及其制备方法和应用 |
AU2014236455B2 (en) | 2013-03-14 | 2018-07-12 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
EP4302736A3 (de) | 2013-03-28 | 2024-04-03 | ForSight Vision4, Inc. | Ophthalmisches implantat zur abgabe von therapeutischen substanzen |
MY182793A (en) | 2014-08-08 | 2021-02-05 | Forsight Vision4 Inc | Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof |
CN108430405B (zh) | 2015-11-20 | 2021-04-13 | 弗赛特影像4股份有限公司 | 用于缓释药物递送装置的多孔结构 |
WO2019103906A1 (en) | 2017-11-21 | 2019-05-31 | Forsight Vision4, Inc. | Fluid exchange apparatus for expandable port delivery system and methods of use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB860371A (en) * | 1958-07-03 | 1961-02-01 | Pfizer & Co C | Di-sulfonamides and compositions containing them |
GB851287A (en) * | 1958-07-10 | 1960-10-12 | British Drug Houses Ltd | 5-chlorotoluene-2:4-disulphonamide and alkali metal salts thereof |
US4077407A (en) * | 1975-11-24 | 1978-03-07 | Alza Corporation | Osmotic devices having composite walls |
US4008719A (en) * | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
-
1980
- 1980-01-28 AT AT80400129T patent/ATE9059T1/de not_active IP Right Cessation
- 1980-01-28 EP EP80400129A patent/EP0033042B1/de not_active Expired
- 1980-01-28 DE DE8080400129T patent/DE3068986D1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0033042A1 (de) | 1981-08-05 |
EP0033042B1 (de) | 1984-08-22 |
ATE9059T1 (de) | 1984-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |