DE3066747D1 - Rhodomycin-group of antibiotics and process for preparing same - Google Patents
Rhodomycin-group of antibiotics and process for preparing sameInfo
- Publication number
- DE3066747D1 DE3066747D1 DE8080104020T DE3066747T DE3066747D1 DE 3066747 D1 DE3066747 D1 DE 3066747D1 DE 8080104020 T DE8080104020 T DE 8080104020T DE 3066747 T DE3066747 T DE 3066747T DE 3066747 D1 DE3066747 D1 DE 3066747D1
- Authority
- DE
- Germany
- Prior art keywords
- rhodomycin
- antibiotics
- group
- preparing same
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP54089552A JPS6023679B2 (ja) | 1979-07-13 | 1979-07-13 | ロドマイシン群抗生物質とその製造法 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3066747D1 true DE3066747D1 (en) | 1984-04-05 |
Family
ID=13973978
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8080104020T Expired DE3066747D1 (en) | 1979-07-13 | 1980-07-11 | Rhodomycin-group of antibiotics and process for preparing same |
Country Status (5)
Country | Link |
---|---|
US (1) | US4316011A (de) |
EP (1) | EP0022574B1 (de) |
JP (1) | JPS6023679B2 (de) |
CA (1) | CA1156578A (de) |
DE (1) | DE3066747D1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5731696A (en) * | 1980-08-01 | 1982-02-20 | Sanraku Inc | Anthracycline derivative |
JPS57165399A (en) | 1981-04-03 | 1982-10-12 | Sanraku Inc | Novel anthracycline antibiotic substance and its preparation |
JPS57176995A (en) * | 1981-04-23 | 1982-10-30 | Sanraku Inc | Novel anthracyclinone glycoside and its preparation |
JPS5874694A (ja) * | 1981-10-29 | 1983-05-06 | Sanraku Inc | アントラサイクリン誘導体 |
US4405713A (en) * | 1981-12-28 | 1983-09-20 | Hoffmann-La Roche Inc. | Process for the preparation of optically active anthracycline glycosides A and B |
JPS5982395A (ja) * | 1982-11-02 | 1984-05-12 | Microbial Chem Res Found | アントラサイクリン化合物、その製造法およびその用途 |
IT1155446B (it) * | 1982-12-23 | 1987-01-28 | Erba Farmitalia | Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine |
JPS59148795A (ja) * | 1983-02-08 | 1984-08-25 | Microbial Chem Res Found | アントラサイクリン化合物、その製造法およびその用途 |
DE3323025A1 (de) * | 1983-06-25 | 1985-01-10 | Hoechst Ag, 6230 Frankfurt | Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika |
DE3325957A1 (de) * | 1983-07-19 | 1985-02-07 | Hoechst Ag, 6230 Frankfurt | Anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatika |
JPS6117597A (ja) * | 1984-07-03 | 1986-01-25 | Microbial Chem Res Found | アントラサイクリン化合物 |
DE3425357A1 (de) * | 1984-07-10 | 1986-01-23 | Hoechst Ag, 6230 Frankfurt | 1-hydroxy-cytorhodine, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika |
JPS61236792A (ja) * | 1985-04-12 | 1986-10-22 | Sanraku Inc | 新規アントラサイクリン抗生物質 |
DE3641835A1 (de) * | 1986-12-08 | 1988-06-16 | Behringwerke Ag | Zytostatisch wirksame anthracyclinderivate |
DE3641833A1 (de) * | 1986-12-08 | 1988-06-09 | Behringwerke Ag | Zytostatisch wirksame anthracyclinderivate |
DE3706175A1 (de) * | 1987-02-26 | 1988-09-08 | Behringwerke Ag | Verwendung von lipophilen anthracyclinen zur behandlung "sekundaer" anthracyclin-resistenter tumoren, mittel enthaltend ein lipophiles anthracyclin und verfahren zu seiner herstellung |
DE3709337A1 (de) * | 1987-03-21 | 1988-10-13 | Hoechst Ag | Neue anthracyclin-glycoside, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatika |
US4918172A (en) * | 1987-10-06 | 1990-04-17 | Sanraku Incorporated | Anthracycline antibiotics |
DE3842836A1 (de) * | 1988-12-20 | 1990-06-21 | Behringwerke Ag | Rhodomycine mit einer modifizierten kohlenhydrat-einheit |
EP0387830A3 (de) * | 1989-03-15 | 1991-09-18 | Yamanouchi Pharmaceutical Co. Ltd. | Anthracyclinstoffe, Mikroorganismen für die Herstellung davon und Verfahren zur Herstellung davon |
US20050208037A1 (en) * | 2003-10-21 | 2005-09-22 | Board Of Regents, The University Of Texas System | Thioredoxin increases redox-cycling of anticancer agents thereby sensitizes cancer cells to apoptosis |
WO2014106826A2 (en) * | 2013-01-07 | 2014-07-10 | Piramal Enterprises Limited | Anthracycline analogue and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5134915B2 (de) * | 1974-07-27 | 1976-09-29 | ||
JPS52136159A (en) * | 1976-04-07 | 1977-11-14 | Microbial Chem Res Found | Anti/malignanttumor containing the same as active ingredients |
US4039736A (en) * | 1976-04-15 | 1977-08-02 | Bristol-Myers Company | Antibiotic compounds marcellomycin and musettamycin |
JPS5323961A (en) * | 1976-08-16 | 1978-03-06 | Microbial Chem Res Found | Antitumors |
NL176004C (nl) * | 1976-10-05 | 1985-02-01 | Microbial Chem Res Found | Werkwijze ter bereiding van geneesmiddelen met antitumorwerking op basis van anthracycline glycosiden en werkwijze ter bereiding van daartoe dienende anthracycline glycosiden. |
JPS5543012A (en) * | 1978-09-20 | 1980-03-26 | Sanraku Inc | Novel anthracycline derivatine and its preparation |
-
1979
- 1979-07-13 JP JP54089552A patent/JPS6023679B2/ja not_active Expired
-
1980
- 1980-06-30 US US06/164,756 patent/US4316011A/en not_active Expired - Lifetime
- 1980-07-09 CA CA000355800A patent/CA1156578A/en not_active Expired
- 1980-07-11 EP EP80104020A patent/EP0022574B1/de not_active Expired
- 1980-07-11 DE DE8080104020T patent/DE3066747D1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
US4316011A (en) | 1982-02-16 |
JPS5615299A (en) | 1981-02-14 |
EP0022574A1 (de) | 1981-01-21 |
CA1156578A (en) | 1983-11-08 |
EP0022574B1 (de) | 1984-02-29 |
JPS6023679B2 (ja) | 1985-06-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: SANRAKU INC., TOKIO/TOKYO, JP |
|
8339 | Ceased/non-payment of the annual fee |