DE3066747D1 - Rhodomycin-group of antibiotics and process for preparing same - Google Patents

Rhodomycin-group of antibiotics and process for preparing same

Info

Publication number
DE3066747D1
DE3066747D1 DE8080104020T DE3066747T DE3066747D1 DE 3066747 D1 DE3066747 D1 DE 3066747D1 DE 8080104020 T DE8080104020 T DE 8080104020T DE 3066747 T DE3066747 T DE 3066747T DE 3066747 D1 DE3066747 D1 DE 3066747D1
Authority
DE
Germany
Prior art keywords
rhodomycin
antibiotics
group
preparing same
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080104020T
Other languages
English (en)
Inventor
Toshikazu Oki
Akihiro Yoshimoto
Yasue Matsuzawa
Taiji Inui
Tomio Takeuchi
Hamao Umezawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanraku Inc
Original Assignee
Sanraku Ocean Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanraku Ocean Co Ltd filed Critical Sanraku Ocean Co Ltd
Application granted granted Critical
Publication of DE3066747D1 publication Critical patent/DE3066747D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE8080104020T 1979-07-13 1980-07-11 Rhodomycin-group of antibiotics and process for preparing same Expired DE3066747D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54089552A JPS6023679B2 (ja) 1979-07-13 1979-07-13 ロドマイシン群抗生物質とその製造法

Publications (1)

Publication Number Publication Date
DE3066747D1 true DE3066747D1 (en) 1984-04-05

Family

ID=13973978

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080104020T Expired DE3066747D1 (en) 1979-07-13 1980-07-11 Rhodomycin-group of antibiotics and process for preparing same

Country Status (5)

Country Link
US (1) US4316011A (de)
EP (1) EP0022574B1 (de)
JP (1) JPS6023679B2 (de)
CA (1) CA1156578A (de)
DE (1) DE3066747D1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5731696A (en) * 1980-08-01 1982-02-20 Sanraku Inc Anthracycline derivative
JPS57165399A (en) 1981-04-03 1982-10-12 Sanraku Inc Novel anthracycline antibiotic substance and its preparation
JPS57176995A (en) * 1981-04-23 1982-10-30 Sanraku Inc Novel anthracyclinone glycoside and its preparation
JPS5874694A (ja) * 1981-10-29 1983-05-06 Sanraku Inc アントラサイクリン誘導体
US4405713A (en) * 1981-12-28 1983-09-20 Hoffmann-La Roche Inc. Process for the preparation of optically active anthracycline glycosides A and B
JPS5982395A (ja) * 1982-11-02 1984-05-12 Microbial Chem Res Found アントラサイクリン化合物、その製造法およびその用途
IT1155446B (it) * 1982-12-23 1987-01-28 Erba Farmitalia Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine
JPS59148795A (ja) * 1983-02-08 1984-08-25 Microbial Chem Res Found アントラサイクリン化合物、その製造法およびその用途
DE3323025A1 (de) * 1983-06-25 1985-01-10 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika
DE3325957A1 (de) * 1983-07-19 1985-02-07 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatika
JPS6117597A (ja) * 1984-07-03 1986-01-25 Microbial Chem Res Found アントラサイクリン化合物
DE3425357A1 (de) * 1984-07-10 1986-01-23 Hoechst Ag, 6230 Frankfurt 1-hydroxy-cytorhodine, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika
JPS61236792A (ja) * 1985-04-12 1986-10-22 Sanraku Inc 新規アントラサイクリン抗生物質
DE3641835A1 (de) * 1986-12-08 1988-06-16 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
DE3641833A1 (de) * 1986-12-08 1988-06-09 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
DE3706175A1 (de) * 1987-02-26 1988-09-08 Behringwerke Ag Verwendung von lipophilen anthracyclinen zur behandlung "sekundaer" anthracyclin-resistenter tumoren, mittel enthaltend ein lipophiles anthracyclin und verfahren zu seiner herstellung
DE3709337A1 (de) * 1987-03-21 1988-10-13 Hoechst Ag Neue anthracyclin-glycoside, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatika
US4918172A (en) * 1987-10-06 1990-04-17 Sanraku Incorporated Anthracycline antibiotics
DE3842836A1 (de) * 1988-12-20 1990-06-21 Behringwerke Ag Rhodomycine mit einer modifizierten kohlenhydrat-einheit
EP0387830A3 (de) * 1989-03-15 1991-09-18 Yamanouchi Pharmaceutical Co. Ltd. Anthracyclinstoffe, Mikroorganismen für die Herstellung davon und Verfahren zur Herstellung davon
US20050208037A1 (en) * 2003-10-21 2005-09-22 Board Of Regents, The University Of Texas System Thioredoxin increases redox-cycling of anticancer agents thereby sensitizes cancer cells to apoptosis
WO2014106826A2 (en) * 2013-01-07 2014-07-10 Piramal Enterprises Limited Anthracycline analogue and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5134915B2 (de) * 1974-07-27 1976-09-29
JPS52136159A (en) * 1976-04-07 1977-11-14 Microbial Chem Res Found Anti/malignanttumor containing the same as active ingredients
US4039736A (en) * 1976-04-15 1977-08-02 Bristol-Myers Company Antibiotic compounds marcellomycin and musettamycin
JPS5323961A (en) * 1976-08-16 1978-03-06 Microbial Chem Res Found Antitumors
NL176004C (nl) * 1976-10-05 1985-02-01 Microbial Chem Res Found Werkwijze ter bereiding van geneesmiddelen met antitumorwerking op basis van anthracycline glycosiden en werkwijze ter bereiding van daartoe dienende anthracycline glycosiden.
JPS5543012A (en) * 1978-09-20 1980-03-26 Sanraku Inc Novel anthracycline derivatine and its preparation

Also Published As

Publication number Publication date
US4316011A (en) 1982-02-16
JPS5615299A (en) 1981-02-14
EP0022574A1 (de) 1981-01-21
CA1156578A (en) 1983-11-08
EP0022574B1 (de) 1984-02-29
JPS6023679B2 (ja) 1985-06-08

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SANRAKU INC., TOKIO/TOKYO, JP

8339 Ceased/non-payment of the annual fee