DE2965881D1 - Acidic uricase, its production and its use for the determination of uric acid - Google Patents

Acidic uricase, its production and its use for the determination of uric acid

Info

Publication number
DE2965881D1
DE2965881D1 DE7979105194T DE2965881T DE2965881D1 DE 2965881 D1 DE2965881 D1 DE 2965881D1 DE 7979105194 T DE7979105194 T DE 7979105194T DE 2965881 T DE2965881 T DE 2965881T DE 2965881 D1 DE2965881 D1 DE 2965881D1
Authority
DE
Germany
Prior art keywords
uricase
acidic
determination
production
uric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979105194T
Other languages
English (en)
Inventor
Toru Nakanishi
Yoshimi Shigemasa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of DE2965881D1 publication Critical patent/DE2965881D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
    • C12N9/0046—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7) with oxygen as acceptor (1.7.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/62—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving uric acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
DE7979105194T 1978-12-14 1979-12-14 Acidic uricase, its production and its use for the determination of uric acid Expired DE2965881D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53153648A JPS6031472B2 (ja) 1978-12-14 1978-12-14 酸性ウリカ−ゼ

Publications (1)

Publication Number Publication Date
DE2965881D1 true DE2965881D1 (en) 1983-08-18

Family

ID=15567123

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979105194T Expired DE2965881D1 (en) 1978-12-14 1979-12-14 Acidic uricase, its production and its use for the determination of uric acid

Country Status (4)

Country Link
US (2) US4273874A (de)
EP (1) EP0012446B1 (de)
JP (1) JPS6031472B2 (de)
DE (1) DE2965881D1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1141061B (it) * 1980-09-19 1986-10-01 Anic Spa Procedimento per la produzione di uricasi
DE3126759A1 (de) * 1981-07-07 1983-01-27 Boehringer Mannheim Gmbh, 6800 Mannheim Loesliche leber-uricase, verfahren zu ihrer herstellung und verwendung
US5175088A (en) * 1983-03-08 1992-12-29 Oriental Yeast Co. Ltd. Rapid analysis of plural components
JPS59163555A (ja) * 1983-03-08 1984-09-14 Oriental Yeast Co Ltd 複数成分の迅速な分析方法
EP0355864A3 (de) * 1984-03-15 1991-09-18 Wako Pure Chemical Industries, Ltd. Verfahren zur quantativen Bemessung von oxydativen Agenzien durch Verwendung von Triphenylmethanleucoverbindungen als Farbstoffe
EP0195320B1 (de) * 1985-03-19 1991-06-12 Abbott Laboratories Diagnostische Probe, die Mikroperoxidase verwendet
US5728562A (en) * 1988-08-17 1998-03-17 Toyo Boseki Kabushiki Kaisha Isolated recombinant uricase
EP2158923B1 (de) 1998-08-06 2013-02-27 Mountain View Pharmaceuticals, Inc. Peg-uricase Konjugate und Verwendung davon
US6913915B2 (en) * 2001-08-02 2005-07-05 Phoenix Pharmacologics, Inc. PEG-modified uricase
RU2435847C2 (ru) 2005-04-11 2011-12-10 Савиент Фармасьютикалз, Инк. Вариантная форма урат-оксидазы и ее использование
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
PL3321359T3 (pl) 2005-04-11 2021-06-28 Horizon Pharma Rheumatology Llc Wariantowe postacie oksydazy moczanowej i ich zastosowanie
US8148123B2 (en) * 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
WO2006125452A1 (en) * 2005-05-23 2006-11-30 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
ES2532804T3 (es) * 2006-04-12 2015-03-31 Crealta Pharmaceuticals Llc Purificación de proteínas con tensioactivo catiónico
KR101861547B1 (ko) 2009-06-25 2018-07-02 크레알타 파마슈티칼스 엘엘씨 페길화된 유리카아제 치료 중에 혈청 요산을 모니터링하여 주입 반응의 위험성 및 반응의 항체­매개 상실을 예측하는 방법 및 키트

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1104197A (en) * 1965-07-28 1968-02-21 Ono Pharmaceutical Co Method of producing uricase from yeast
US3431176A (en) * 1966-02-02 1969-03-04 Toyo Boseki Preparation of uricase
FR1529675A (fr) * 1967-03-29 1968-06-21 Applic Biochimiques Soc Et Urate oxydase à haute activité et sa préparation
GB1221235A (en) * 1968-08-19 1971-02-03 Novo Terapeutisk Labor As A process for the production of uricase
US3616231A (en) * 1968-11-14 1971-10-26 Boehringer Mannheim Gmbh Process for the production of uricase
JPS5033795B1 (de) * 1970-11-25 1975-11-04
DE2164018C3 (de) * 1970-12-26 1973-11-15 Noda Institute For Scientific Research, Noda (Japan) Verfahren zur biotechnischen Her stellung von Uncase
US4064010A (en) * 1976-07-21 1977-12-20 Eastman Kodak Company Purification of uricase
US4062731A (en) * 1976-07-21 1977-12-13 Eastman Kodak Company Production of uricase from micrococcus luteus
FR2383443A1 (fr) * 1977-03-07 1978-10-06 Bretaudiere Jean Pierre Procede de dosage enzymatique de l'acide urique
DE2718588C3 (de) * 1977-04-26 1979-11-08 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Reagens zur Bestimmung von Harnsäure

Also Published As

Publication number Publication date
JPS5581586A (en) 1980-06-19
JPS6031472B2 (ja) 1985-07-22
EP0012446A1 (de) 1980-06-25
EP0012446B1 (de) 1983-07-13
US4273874A (en) 1981-06-16
US4317878A (en) 1982-03-02

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee