DE2963757D1 - Apparatus for non-invasive detection of zinc protoporphyrin in erythrocytes - Google Patents
Apparatus for non-invasive detection of zinc protoporphyrin in erythrocytesInfo
- Publication number
- DE2963757D1 DE2963757D1 DE7979300008T DE2963757T DE2963757D1 DE 2963757 D1 DE2963757 D1 DE 2963757D1 DE 7979300008 T DE7979300008 T DE 7979300008T DE 2963757 T DE2963757 T DE 2963757T DE 2963757 D1 DE2963757 D1 DE 2963757D1
- Authority
- DE
- Germany
- Prior art keywords
- erythrocytes
- invasive detection
- zinc protoporphyrin
- protoporphyrin
- zinc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000001514 detection method Methods 0.000 title 1
- 210000003743 erythrocyte Anatomy 0.000 title 1
- FUTVBRXUIKZACV-UHFFFAOYSA-J zinc;3-[18-(2-carboxylatoethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoate Chemical compound [Zn+2].[N-]1C2=C(C)C(CCC([O-])=O)=C1C=C([N-]1)C(CCC([O-])=O)=C(C)C1=CC(C(C)=C1C=C)=NC1=CC(C(C)=C1C=C)=NC1=C2 FUTVBRXUIKZACV-UHFFFAOYSA-J 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14556—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases by fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Optics & Photonics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86678878A | 1978-01-03 | 1978-01-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE2963757D1 true DE2963757D1 (en) | 1982-11-11 |
Family
ID=25348410
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE7979300008T Expired DE2963757D1 (en) | 1978-01-03 | 1979-01-03 | Apparatus for non-invasive detection of zinc protoporphyrin in erythrocytes |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP0003015B1 (de) |
DE (1) | DE2963757D1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK178879A (da) * | 1979-05-01 | 1980-11-02 | Bioteknisk Inst | Fremgangsmaade til direkte profylaktisk forraadnelsesregistrerig af foedevaregenstande navnlig bestemmelse af phoma- og/ellerfusariumangreb paa kartofter samt apparat til udoevelse af fremgangsmaaden |
EP0059032A1 (de) * | 1981-02-03 | 1982-09-01 | Virgil B. Elings | Farbstoff-Konzentrationsmessung im Blutstrom |
FR2502783A1 (fr) * | 1981-03-25 | 1982-10-01 | Cilas | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
EP0063431B1 (de) * | 1981-04-10 | 1987-10-28 | Masaaki Konomi | Spektroskopisches Analysensystem |
DE3206407A1 (de) * | 1982-02-23 | 1983-09-01 | Gesellschaft für Strahlen- und Umweltforschung mbH, 8000 München | Einrichtung zum quantitativen nachweis biochemischer reaktionen |
EP0112378B1 (de) * | 1982-06-28 | 1989-01-11 | The Johns Hopkins University | Elektro-optisches gerät zur beobachtung der momentanen singlet-sauerstoff-konzentration während der krebsbehandlung mittels photochemo-therapie |
US4592361A (en) * | 1982-06-28 | 1986-06-03 | The Johns Hopkins University | Electro-optical device and method for monitoring instantaneous singlet oxygen concentration produced during photoradiation using pulsed excitation and time domain signal processing |
DE3323365C2 (de) * | 1982-09-04 | 1994-10-20 | Gsf Forschungszentrum Umwelt | Verfahren und Vorrichtung zur Ausleuchtung von Hohlräumen |
US4541438A (en) * | 1983-06-02 | 1985-09-17 | The Johns Hopkins University | Localization of cancerous tissue by monitoring infrared fluorescence emitted by intravenously injected porphyrin tumor-specific markers excited by long wavelength light |
US4553034A (en) * | 1983-12-02 | 1985-11-12 | Westinghouse Electric Corp. | Ion exchange resin intrusion monitor |
EP0222419A3 (de) * | 1985-11-14 | 1988-07-20 | Instituto De Bioingenieria, Fundacion Carlos Garcia-Monzon | Verfahren zur Bestimmung von labilem glycosyliertem Hämoglobin und Glykämie |
DE4026821A1 (de) * | 1990-08-24 | 1992-03-05 | Philips Patentverwaltung | Verfahren zur erfassung von anomalien der haut, insbesondere von melanomen, sowie vorrichtung zur durchfuehrung des verfahrens |
DE69221878T2 (de) * | 1991-07-03 | 1998-03-26 | Vivascan Corp., Southboro, Ma. | Verfahren und vorrichtung zur elektromagnetischen bestimmung von im lebenden gewebe vorliegenden substanzen |
GB9521784D0 (en) * | 1995-10-24 | 1996-01-03 | Rosslyn Medical Ltd | Diagnostic apparatus |
US6008889A (en) * | 1997-04-16 | 1999-12-28 | Zeng; Haishan | Spectrometer system for diagnosis of skin disease |
DE69940787D1 (de) | 1999-09-30 | 2009-06-04 | Diagnoptics Holding B V | Verfahren und gerät zur bestimmung der autofluoreszenz von hautgewebe |
US11490816B2 (en) | 2015-02-18 | 2022-11-08 | Ferrosens Gmbh | Apparatus and method for fluorescence measurements on tissue for the determination of blood fluorophores |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3536898A (en) * | 1967-12-04 | 1970-10-27 | Us Navy | Detection device |
US3811777A (en) * | 1973-02-06 | 1974-05-21 | Johnson Res Foundation Medical | Time-sharing fluorometer and reflectometer |
US3999062A (en) * | 1975-10-01 | 1976-12-21 | International Business Machines Corporation | Spectrophotometer for dual mode fluorescence analysis |
DE2630606A1 (de) * | 1976-07-07 | 1978-01-12 | Alois Hoerl | Vorrichtung zur analyse der luminiszenzstrahlung von stoffen, insbesondere von lebender substanz |
-
1979
- 1979-01-03 EP EP19790300008 patent/EP0003015B1/de not_active Expired
- 1979-01-03 DE DE7979300008T patent/DE2963757D1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0003015A1 (de) | 1979-07-11 |
EP0003015B1 (de) | 1982-09-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |