DE2708706A1 - Ueberfuehrungseinrichtung zwischen einem fluessigkeits-chromatographen und einem massenspektrometer - Google Patents

Ueberfuehrungseinrichtung zwischen einem fluessigkeits-chromatographen und einem massenspektrometer

Info

Publication number
DE2708706A1
DE2708706A1 DE19772708706 DE2708706A DE2708706A1 DE 2708706 A1 DE2708706 A1 DE 2708706A1 DE 19772708706 DE19772708706 DE 19772708706 DE 2708706 A DE2708706 A DE 2708706A DE 2708706 A1 DE2708706 A1 DE 2708706A1
Authority
DE
Germany
Prior art keywords
mass spectrometer
transfer device
solution
liquid chromatograph
ionization chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19772708706
Other languages
German (de)
English (en)
Inventor
William Hamilton Mcfadden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Finnigan LLC
Original Assignee
Finnigan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finnigan Corp filed Critical Finnigan Corp
Publication of DE2708706A1 publication Critical patent/DE2708706A1/de
Pending legal-status Critical Current

Links

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0468Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample
    • H01J49/049Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample with means for applying heat to desorb the sample; Evaporation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/728Intermediate storage of effluent, including condensation on surface
    • G01N30/7286Intermediate storage of effluent, including condensation on surface the store moving as a whole, e.g. moving wire

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
DE19772708706 1976-03-04 1977-03-01 Ueberfuehrungseinrichtung zwischen einem fluessigkeits-chromatographen und einem massenspektrometer Pending DE2708706A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/664,058 US4055987A (en) 1976-03-04 1976-03-04 Liquid chromatograph/mass spectrometer interface

Publications (1)

Publication Number Publication Date
DE2708706A1 true DE2708706A1 (de) 1978-02-02

Family

ID=24664341

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772708706 Pending DE2708706A1 (de) 1976-03-04 1977-03-01 Ueberfuehrungseinrichtung zwischen einem fluessigkeits-chromatographen und einem massenspektrometer

Country Status (5)

Country Link
US (1) US4055987A (https=)
JP (1) JPS52117191A (https=)
DE (1) DE2708706A1 (https=)
GB (1) GB1543014A (https=)
SE (1) SE432024B (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2654057B1 (de) * 1976-11-29 1978-04-27 Varian Mat Gmbh Verfahren zur Ionisierung von organischen Substanzen,sowie dieses Verfahren benutzendes Analysegeraet
US4281246A (en) * 1979-10-12 1981-07-28 The United States Of America As Represented By The Administrator Of The United States Environmental Protection Agency Continuous-flow solution concentrator and liquid chromatograph/mass spectrometer interface and methods for using both
WO1981003394A1 (en) * 1980-05-23 1981-11-26 Research Corp Ion vapor source for mass spectrometry of liquids
US4552723A (en) * 1983-08-01 1985-11-12 International Business Machines Corporation LC/FTIR System with thermospray solvent separation
US4960992A (en) * 1983-08-30 1990-10-02 Research Corporation Technologies Method and means for vaporizing liquids by means of heating a sample capillary tube for detection or analysis
US4861989A (en) * 1983-08-30 1989-08-29 Research Corporation Technologies, Inc. Ion vapor source for mass spectrometry of liquids
US4814612A (en) * 1983-08-30 1989-03-21 Research Corporation Method and means for vaporizing liquids for detection or analysis
DE3576882D1 (de) * 1984-02-17 1990-05-03 American Cyanamid Co Verfahren und vorrichtung zum ueberfuehren einer fluessigen probe aus einem fluessigkeitschromatographen in ein massenspektrometer mit chemischer ionisierung.
JPS59210357A (ja) * 1984-04-27 1984-11-29 Hitachi Ltd 液体クロマトグラフ−質量分析計結合分析装置
US4629478A (en) * 1984-06-22 1986-12-16 Georgia Tech Research Corporation Monodisperse aerosol generator
US4924097A (en) * 1984-06-22 1990-05-08 Georgia Tech Rss. Corp Monodisperse aerosol generator for use with infrared spectrometry
US4687929A (en) * 1984-06-22 1987-08-18 Georgia Tech Research Corporation Monodisperse aerosol generator
US4762995A (en) * 1984-06-22 1988-08-09 Georgia Tech Research Corporation Monodisperse aerosol generator
US4843243A (en) * 1986-04-14 1989-06-27 Massachusetts Institute Of Technology Method and apparatus for continuous collection of chromatographic effluent
US4867947A (en) * 1986-09-08 1989-09-19 Sepragen Corporation Interface for liquid chromatograph-mass spectrometer
US4740298A (en) * 1986-09-08 1988-04-26 Sepragen Corporation Chromatography column/moving belt interface
US4708782A (en) * 1986-09-15 1987-11-24 Sepragen Corporation Chromatography column-electrophoresis system
US4801430A (en) * 1986-09-25 1989-01-31 Trustees Of Tufts College Interface for separating an analyte of interest from a liquid solvent
JPS63266756A (ja) * 1987-04-23 1988-11-02 Jeol Ltd 質量分析装置用イオン源
US4883958A (en) * 1988-12-16 1989-11-28 Vestec Corporation Interface for coupling liquid chromatography to solid or gas phase detectors
US5083450A (en) * 1990-05-18 1992-01-28 Martin Marietta Energy Systems, Inc. Gas chromatograph-mass spectrometer (gc/ms) system for quantitative analysis of reactive chemical compounds
US5266192A (en) * 1991-09-12 1993-11-30 General Electric Company Apparatus for interfacing liquid chromatograph with magnetic sector spectrometer
US5238653A (en) * 1991-10-15 1993-08-24 Bio-Rad Laboratories, Inc. Sample concentrator/solvent exchange system
US5272337A (en) * 1992-04-08 1993-12-21 Martin Marietta Energy Systems, Inc. Sample introducing apparatus and sample modules for mass spectrometer
US6309600B1 (en) * 1997-08-28 2001-10-30 Biotrove, Inc. Apparatus for droplet microchemistry
US6191418B1 (en) 1998-03-27 2001-02-20 Synsorb Biotech, Inc. Device for delivery of multiple liquid sample streams to a mass spectrometer
GB2363517B (en) * 2000-03-31 2004-09-08 Mass Spec Analytical Ltd Analytical apparatus
US20050123970A1 (en) * 2001-04-25 2005-06-09 Can Ozbal High throughput autosampler
US8414774B2 (en) * 2001-04-25 2013-04-09 Agilent Technologies, Inc. Systems and methods for high-throughput screening of fluidic samples
US7588725B2 (en) * 2001-04-25 2009-09-15 Biotrove, Inc. High throughput autosampler
US6902937B2 (en) * 2001-07-13 2005-06-07 Air Liquide America, L.P. Method for the determination of low-concentration anions in the presence of an excess of another anion
DE10216975B4 (de) * 2002-04-16 2007-10-18 Thermo Electron (Bremen) Gmbh Verfahren und Vorrichtung zur Bereitstellung von Gas für die Isotopenverhältnisanalyse
US7964411B2 (en) * 2007-06-12 2011-06-21 Dionex Corporation Membrane based concentrators
EP2217903B1 (en) * 2007-11-02 2019-04-03 Biocius Life Sciences, Inc. Sample injection system
US20100276589A1 (en) * 2009-05-04 2010-11-04 M&M Mass Spec Consulting Llc Atmospheric pressure ion source moving transport interface for a mass spectrometer
US10304667B1 (en) * 2017-12-14 2019-05-28 Thermo Finnigan Llc Apparatus and method for cleaning an inlet of a mass spectrometer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3128619A (en) * 1961-03-24 1964-04-14 Packard Instrument Co Inc Method of and apparatus for monitoring for flowing stream content
GB1241420A (en) * 1967-12-13 1971-08-04 Pye Ltd Improvements in liquid-liquid chromatography
US3566677A (en) * 1969-06-26 1971-03-02 Atomic Energy Commission Method and apparatus for monitoring content of flowing streams
CS150104B1 (https=) * 1970-08-11 1973-09-04
JPS475679U (https=) * 1971-02-10 1972-09-19
US3788479A (en) * 1972-04-13 1974-01-29 Shell Oil Co Disc conveyor flame ionization detectors
US3929004A (en) * 1972-12-15 1975-12-30 Ici Australia Ltd Method and apparatus for monitoring materials dissolved or suspended in liquid

Also Published As

Publication number Publication date
US4055987A (en) 1977-11-01
JPS5651583B2 (https=) 1981-12-07
JPS52117191A (en) 1977-10-01
GB1543014A (en) 1979-03-28
SE7702354L (sv) 1977-09-05
SE432024B (sv) 1984-03-12

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