DE2239648A1 - Polycyclische verbindungen - Google Patents
Polycyclische verbindungenInfo
- Publication number
- DE2239648A1 DE2239648A1 DE2239648A DE2239648A DE2239648A1 DE 2239648 A1 DE2239648 A1 DE 2239648A1 DE 2239648 A DE2239648 A DE 2239648A DE 2239648 A DE2239648 A DE 2239648A DE 2239648 A1 DE2239648 A1 DE 2239648A1
- Authority
- DE
- Germany
- Prior art keywords
- formula
- hydroxy
- methyl
- lower alkoxy
- pyridyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17174371A | 1971-08-13 | 1971-08-13 | |
| US26733072A | 1972-06-29 | 1972-06-29 | |
| US275598A US3862953A (en) | 1971-08-13 | 1972-07-27 | Cycloalkene(B)indoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2239648A1 true DE2239648A1 (de) | 1973-02-22 |
Family
ID=27390018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2239648A Pending DE2239648A1 (de) | 1971-08-13 | 1972-08-11 | Polycyclische verbindungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3862953A (OSRAM) |
| AT (1) | AT319244B (OSRAM) |
| AU (1) | AU468678B2 (OSRAM) |
| BE (1) | BE787444A (OSRAM) |
| CA (1) | CA981681A (OSRAM) |
| DE (1) | DE2239648A1 (OSRAM) |
| FR (1) | FR2150761B1 (OSRAM) |
| GB (1) | GB1382513A (OSRAM) |
| NL (1) | NL7211013A (OSRAM) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0471298A1 (en) * | 1990-08-13 | 1992-02-19 | Hoechst-Roussel Pharmaceuticals Incorporated | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs |
| US5455245A (en) * | 1990-08-13 | 1995-10-03 | Hoechst-Roussel Pharmaceuticals Inc. | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4018778A (en) * | 1972-05-24 | 1977-04-19 | Cassella Farbwerke Mainkur Aktiengesellschaft | Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production |
| LU69043A1 (OSRAM) * | 1973-12-20 | 1975-08-20 | ||
| US4486593A (en) * | 1983-01-19 | 1984-12-04 | The Upjohn Company | 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors |
| US4696930A (en) * | 1985-04-12 | 1987-09-29 | Hoffmann-La Roche Inc. | N-(heteroarylalkyl)acylanilide derivatives as antiarrhythmic agents |
| US5187180A (en) * | 1990-07-26 | 1993-02-16 | Merck Frosst Canada, Inc. | (quinolin-2-ylmethoxy)heterotetrahydrocarbazoles as inhibitors of the biosynthesis of leukotrienes |
| US5221678A (en) * | 1990-07-26 | 1993-06-22 | Merck Frosst Canada, Inc. | (quinolin-2-ylmethoxy)tetrahydrocarbazoles as inhibitors of the biosynthesis of leukotrienes |
| CA2128283A1 (fr) * | 1993-07-20 | 1995-01-21 | Paul Caubere | (thia)cycloalkyl¬b|indoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2720064B1 (fr) * | 1994-05-19 | 1996-06-28 | Adir | Thiacycloalkyl [b] indoles, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| US6410583B1 (en) | 2000-07-25 | 2002-06-25 | Merck Frosst Canada & Co. | Cyclopentanoindoles, compositions containing such compounds and methods of treatment |
| DE10164564B4 (de) * | 2001-12-14 | 2007-05-16 | Zentaris Gmbh | Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR) |
| AR038136A1 (es) * | 2002-01-24 | 2004-12-29 | Merck Frosst Canada Inc | Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento |
| AR041089A1 (es) * | 2003-05-15 | 2005-05-04 | Merck & Co Inc | Procedimiento y composiciones farmaceutiicas para tratar aterosclerosis, dislipidemias y afecciones relacionadas |
| WO2008097535A2 (en) * | 2007-02-08 | 2008-08-14 | Merck & Co., Inc. | Method of treating atherosclerosis, dyslipidemias and related conditions |
| JP5246715B2 (ja) * | 2009-01-27 | 2013-07-24 | 独立行政法人科学技術振興機構 | 蛋白質架橋阻害剤およびその用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2016480A (en) * | 1932-03-31 | 1935-10-08 | Winthrop Chem Co Inc | Perhydrocarbazyl compounds of the pyridine and quinoline series |
| US3154556A (en) * | 1962-12-04 | 1964-10-27 | American Home Prod | Nu-pyridylethyl-2:3-polymethyleneindoles |
-
0
- BE BE787444D patent/BE787444A/xx unknown
-
1972
- 1972-07-27 US US275598A patent/US3862953A/en not_active Expired - Lifetime
- 1972-08-10 FR FR7228899A patent/FR2150761B1/fr not_active Expired
- 1972-08-11 GB GB3756772A patent/GB1382513A/en not_active Expired
- 1972-08-11 CA CA149,205A patent/CA981681A/en not_active Expired
- 1972-08-11 NL NL7211013A patent/NL7211013A/xx unknown
- 1972-08-11 AT AT696872A patent/AT319244B/de not_active IP Right Cessation
- 1972-08-11 AU AU45528/72A patent/AU468678B2/en not_active Expired
- 1972-08-11 DE DE2239648A patent/DE2239648A1/de active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0471298A1 (en) * | 1990-08-13 | 1992-02-19 | Hoechst-Roussel Pharmaceuticals Incorporated | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs |
| US5455245A (en) * | 1990-08-13 | 1995-10-03 | Hoechst-Roussel Pharmaceuticals Inc. | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs |
| US5688816A (en) * | 1990-08-13 | 1997-11-18 | Hoechst Marion Roussel, Inc. | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2150761B1 (OSRAM) | 1975-08-08 |
| GB1382513A (en) | 1975-02-05 |
| CA981681A (en) | 1976-01-13 |
| NL7211013A (OSRAM) | 1973-02-15 |
| AT319244B (de) | 1974-12-10 |
| FR2150761A1 (OSRAM) | 1973-04-13 |
| AU468678B2 (en) | 1976-01-22 |
| AU4552872A (en) | 1974-02-14 |
| BE787444A (fr) | 1973-02-12 |
| US3862953A (en) | 1975-01-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHJ | Non-payment of the annual fee |