DE2215539C2 - Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate - Google Patents

Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate

Info

Publication number
DE2215539C2
DE2215539C2 DE2215539A DE2215539A DE2215539C2 DE 2215539 C2 DE2215539 C2 DE 2215539C2 DE 2215539 A DE2215539 A DE 2215539A DE 2215539 A DE2215539 A DE 2215539A DE 2215539 C2 DE2215539 C2 DE 2215539C2
Authority
DE
Germany
Prior art keywords
enzyme
water
copolymers
insoluble
anhydride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2215539A
Other languages
German (de)
English (en)
Other versions
DE2215539A1 (de
Inventor
Herbert Dr. 5074 Odenthal Bartl
Bruno Dr. 5090 Leverkusen Bömer
Fritz Dr. Hüper
Erich Dr. Rauenbusch
Günter Dr. 5600 Wuppertal Schmidt-Kastner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to DE2215539A priority Critical patent/DE2215539C2/de
Priority to AU53671/73A priority patent/AU476335B2/en
Priority to EG111/73A priority patent/EG10983A/xx
Priority to CS732221A priority patent/CS187373B2/cs
Priority to IL41885A priority patent/IL41885A/en
Priority to SU1898251A priority patent/SU537630A3/ru
Priority to TR17150A priority patent/TR17150A/xx
Priority to NL7304330A priority patent/NL7304330A/xx
Priority to AT401674A priority patent/AT324998B/de
Priority to IT22281/73A priority patent/IT1003075B/it
Priority to LU67317A priority patent/LU67317A1/xx
Priority to CA167,348A priority patent/CA1036746A/en
Priority to DD179523*A priority patent/DD114083A5/xx
Priority to AT271573A priority patent/AT324264B/de
Priority to FI730959A priority patent/FI52732C/fi
Priority to DD169798A priority patent/DD108099A5/xx
Priority to US345792A priority patent/US3910825A/en
Priority to BR732272A priority patent/BR7302272D0/pt
Priority to PL1973161580A priority patent/PL91817B1/pl
Priority to BE129411A priority patent/BE797501A/xx
Priority to HUBA2900A priority patent/HU167411B/hu
Priority to IE502/73A priority patent/IE37474B1/xx
Priority to GB2360075A priority patent/GB1413383A/en
Priority to GB1511473A priority patent/GB1413381A/en
Priority to ES413132A priority patent/ES413132A1/es
Priority to CH456173A priority patent/CH594009A5/xx
Priority to IE265/76A priority patent/IE37475B1/xx
Priority to ZA732180A priority patent/ZA732180B/xx
Priority to DK173173A priority patent/DK137800C/da
Priority to AR247319A priority patent/AR199202A1/es
Priority to FR7311601A priority patent/FR2186479B1/fr
Priority to SE7304529A priority patent/SE420202B/xx
Priority to BG033187A priority patent/BG25232A3/xx
Priority to BG7300323086A priority patent/BG25230A3/xx
Publication of DE2215539A1 publication Critical patent/DE2215539A1/de
Priority to AT292674A priority patent/AT331972B/de
Priority to IT29408/74A priority patent/IT1030795B/it
Priority to AT1008974A priority patent/AT336274B/de
Priority to IN198/CAL/75A priority patent/IN138647B/en
Priority to SU752106088A priority patent/SU589930A3/ru
Priority to IT20913/75A priority patent/IT1033414B/it
Priority to US05/636,569 priority patent/US4044196A/en
Priority to HK383/76*UA priority patent/HK38376A/xx
Priority to CS772654A priority patent/CS187397B2/cs
Priority to CS772655A priority patent/CS187398B2/cs
Priority to CA303,249A priority patent/CA1052045A/en
Application granted granted Critical
Publication of DE2215539C2 publication Critical patent/DE2215539C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10—Esters
    • C08F20/20—Esters of polyhydric alcohols or polyhydric phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/816—Attached to the carrier via a bridging agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
DE2215539A 1972-03-30 1972-03-30 Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate Expired DE2215539C2 (de)

Priority Applications (45)

Application Number Priority Date Filing Date Title
DE2215539A DE2215539C2 (de) 1972-03-30 1972-03-30 Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate
AU53671/73A AU476335B2 (en) 1972-03-30 1973-03-22 New water-insoluble preparations of peptide materials, their production and their use
EG111/73A EG10983A (en) 1972-03-30 1973-03-24 A process for preparation of new water-insoluble peptide materials and their use
CS732221A CS187373B2 (en) 1972-03-30 1973-03-27 Method of producing water-insoluble protein preparations
IL41885A IL41885A (en) 1972-03-30 1973-03-27 Water-insoluble preparations of peptide materials,their production and their use
SU1898251A SU537630A3 (ru) 1972-03-30 1973-03-27 Способ получени водонерастворимого препарата фермента
TR17150A TR17150A (tr) 1972-03-30 1973-03-27 Suda coezuenmeyen yeni protein preparatlari
NL7304330A NL7304330A (US06653308-20031125-C00199.png) 1972-03-30 1973-03-28
AT401674A AT324998B (de) 1972-03-30 1973-03-28 Verfahren zur herstellung von neuen wasserunlöslichen proteinpräparaten, insbesondere von neuen wasserunlöslichen penicillinacylasepräparaten
IT22281/73A IT1003075B (it) 1972-03-30 1973-03-28 Preparati proteici idroinsolubili e processo per la loro preparazione
LU67317A LU67317A1 (US06653308-20031125-C00199.png) 1972-03-30 1973-03-28
CA167,348A CA1036746A (en) 1972-03-30 1973-03-28 Water-insoluble preparations of peptide materials, their production and their use
DD179523*A DD114083A5 (US06653308-20031125-C00199.png) 1972-03-30 1973-03-28
AT271573A AT324264B (de) 1972-03-30 1973-03-28 Verfahren zur herstellung von neuen wasserunlöslichen proteinpräparaten, insbesondere von neuen wasserunlöslichen penicillinacylasepräparaten
FI730959A FI52732C (fi) 1972-03-30 1973-03-28 Menetelmä veteenliukenemattoman, verkkoutuneeseen kopolymeraattiin kii nnittyneen entsyymipreparaatin valmistamiseksi.
DD169798A DD108099A5 (US06653308-20031125-C00199.png) 1972-03-30 1973-03-28
US345792A US3910825A (en) 1972-03-30 1973-03-28 Water-insoluble peptide materials
BR732272A BR7302272D0 (pt) 1972-03-30 1973-03-29 Composicoes de proteina insoluveis em agua e processo paracomposicoes de proteina insoluveis em agua e processo para a preparacao das mesmas a preparacao das mesmas
PL1973161580A PL91817B1 (US06653308-20031125-C00199.png) 1972-03-30 1973-03-29
BE129411A BE797501A (fr) 1972-03-30 1973-03-29 Nouvelles preparations de proteines insolubles dans l'eau et leur procede d'obtention
HUBA2900A HU167411B (en) 1972-03-30 1973-03-29 Process for producing water-insoluble protein preparations
IE502/73A IE37474B1 (en) 1972-03-30 1973-03-29 New water-insoluble preparations of peptide materials their production and their use
GB2360075A GB1413383A (en) 1972-03-30 1973-03-29 Cross-linked copolymers and their production
GB1511473A GB1413381A (en) 1972-03-30 1973-03-29 Water-insoluble preparations of peptide materials their production and their use
ES413132A ES413132A1 (es) 1972-03-30 1973-03-29 Procedimiento para la produccion de preparados de proteina insolubles en agua.
CH456173A CH594009A5 (US06653308-20031125-C00199.png) 1972-03-30 1973-03-29
IE265/76A IE37475B1 (en) 1972-03-30 1973-03-29 New cross-linked copolymers and their production
ZA732180A ZA732180B (en) 1972-03-30 1973-03-29 New water-insoluble preparations of peptide materials,their production and their use
DK173173A DK137800C (da) 1972-03-30 1973-03-29 Vanduoploeselige proteinpraeparater og fremgangsmaade til fremstilling deraf
AR247319A AR199202A1 (es) 1972-03-30 1973-03-30 Nuevos preparados de proteina industrialmente aplicables insolubles en agua y procedimiento para su produccion
FR7311601A FR2186479B1 (US06653308-20031125-C00199.png) 1972-03-30 1973-03-30
SE7304529A SE420202B (sv) 1972-03-30 1973-03-30 Nya vattenolosliga proteinpreparat till anvendning for genomforing av medelst enzymer katalyserbara reaktioner
BG033187A BG25232A3 (en) 1972-03-30 1973-05-12 A method of obtaining 6-aminepenicillane acid by means of enzyme splitting of the penicilline
BG7300323086A BG25230A3 (en) 1972-03-30 1973-09-26 A method of obtaining insoluble in water protein preparations
AT292674A AT331972B (de) 1972-03-30 1974-04-08 Durchfuhrung von durch wasserunlosliche proteinpraparate katalysierbarenreaktionen
IT29408/74A IT1030795B (it) 1972-03-30 1974-11-13 Copolimeri reticolati e processo per la loro preparazione
AT1008974A AT336274B (de) 1972-03-30 1974-12-18 Verfahren zur herstellung neuer copolymerisate
IN198/CAL/75A IN138647B (US06653308-20031125-C00199.png) 1972-03-30 1975-02-01
SU752106088A SU589930A3 (ru) 1972-03-30 1975-02-19 Способ получени полимерных носителей протеинов
IT20913/75A IT1033414B (it) 1972-03-30 1975-03-04 Copolimeri reticolati e processo per la loro preparazione
US05/636,569 US4044196A (en) 1972-03-30 1975-12-01 Crosslinked copolymers of α,β-olefinically unsaturated dicarboxylic anhydrides
HK383/76*UA HK38376A (en) 1972-03-30 1976-06-24 New water-insoluble preparations of peptide materials,their production and their use
CS772654A CS187397B2 (en) 1972-03-30 1977-04-21 Process for preparing copolymers
CS772655A CS187398B2 (en) 1972-03-30 1977-04-21 Reaction catalysed by enzymes
CA303,249A CA1052045A (en) 1972-03-30 1978-05-12 Water-insoluble preparations of peptide materials, their production and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2215539A DE2215539C2 (de) 1972-03-30 1972-03-30 Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate

Publications (2)

Publication Number Publication Date
DE2215539A1 DE2215539A1 (de) 1973-10-18
DE2215539C2 true DE2215539C2 (de) 1984-08-02

Family

ID=5840623

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2215539A Expired DE2215539C2 (de) 1972-03-30 1972-03-30 Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate

Country Status (29)

Country Link
US (1) US3910825A (US06653308-20031125-C00199.png)
AR (1) AR199202A1 (US06653308-20031125-C00199.png)
AT (2) AT324998B (US06653308-20031125-C00199.png)
BE (1) BE797501A (US06653308-20031125-C00199.png)
BG (2) BG25232A3 (US06653308-20031125-C00199.png)
BR (1) BR7302272D0 (US06653308-20031125-C00199.png)
CA (1) CA1036746A (US06653308-20031125-C00199.png)
CH (1) CH594009A5 (US06653308-20031125-C00199.png)
CS (1) CS187373B2 (US06653308-20031125-C00199.png)
DD (2) DD108099A5 (US06653308-20031125-C00199.png)
DE (1) DE2215539C2 (US06653308-20031125-C00199.png)
DK (1) DK137800C (US06653308-20031125-C00199.png)
EG (1) EG10983A (US06653308-20031125-C00199.png)
ES (1) ES413132A1 (US06653308-20031125-C00199.png)
FI (1) FI52732C (US06653308-20031125-C00199.png)
FR (1) FR2186479B1 (US06653308-20031125-C00199.png)
GB (1) GB1413381A (US06653308-20031125-C00199.png)
HK (1) HK38376A (US06653308-20031125-C00199.png)
HU (1) HU167411B (US06653308-20031125-C00199.png)
IE (2) IE37475B1 (US06653308-20031125-C00199.png)
IL (1) IL41885A (US06653308-20031125-C00199.png)
IT (3) IT1003075B (US06653308-20031125-C00199.png)
LU (1) LU67317A1 (US06653308-20031125-C00199.png)
NL (1) NL7304330A (US06653308-20031125-C00199.png)
PL (1) PL91817B1 (US06653308-20031125-C00199.png)
SE (1) SE420202B (US06653308-20031125-C00199.png)
SU (2) SU537630A3 (US06653308-20031125-C00199.png)
TR (1) TR17150A (US06653308-20031125-C00199.png)
ZA (1) ZA732180B (US06653308-20031125-C00199.png)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH593992A5 (US06653308-20031125-C00199.png) * 1972-12-23 1977-12-30 Roehm Gmbh
GB1492937A (en) * 1973-12-28 1977-11-23 Beecham Group Ltd Enzyme complexes and their use
US4113566A (en) * 1976-11-26 1978-09-12 Pfizer Inc. Process for preparing 6-aminopenicillanic acid
JPS5664788A (en) * 1979-10-27 1981-06-02 Unitika Ltd Method for imparting enzyme activity to solid surface
DE3136940A1 (de) * 1981-09-17 1983-03-31 Hoechst Ag, 6230 Frankfurt "verfahren zur herstellung von 5'-ribonucleotiden"
US5153166A (en) * 1988-08-18 1992-10-06 Trustees Of At Biochem Chromatographic stationary supports
EP1002064B1 (en) * 1997-06-25 2007-10-10 Novozymes A/S A modified polypeptide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1603393A (US06653308-20031125-C00199.png) * 1967-12-27 1971-04-13
US3650901A (en) * 1968-09-27 1972-03-21 Yeda Res & Dev Polymeric enzyme products
US3577512A (en) * 1968-10-11 1971-05-04 Nat Patent Dev Corp Sustained release tablets
DE1908290C3 (de) * 1969-02-19 1982-04-08 Boehringer Mannheim Gmbh, 6800 Mannheim Acrylamid-mischpolymerisat
US3576760A (en) * 1969-06-13 1971-04-27 Nat Patent Dev Corp Water soluble entrapping

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Also Published As

Publication number Publication date
HU167411B (en) 1975-10-28
IT1030795B (it) 1979-04-10
DK137800B (da) 1978-05-08
DD114083A5 (US06653308-20031125-C00199.png) 1975-07-12
BE797501A (fr) 1973-10-01
HK38376A (en) 1976-07-02
CS187373B2 (en) 1979-01-31
IT1003075B (it) 1976-06-10
IT1033414B (it) 1979-07-10
AU5367173A (en) 1974-09-26
US3910825A (en) 1975-10-07
IE37474B1 (en) 1977-08-03
SU589930A3 (ru) 1978-01-25
IL41885A (en) 1976-03-31
FI52732C (fi) 1977-11-10
DK137800C (da) 1978-10-09
SU537630A3 (ru) 1976-11-30
IE37475B1 (en) 1977-08-03
FR2186479B1 (US06653308-20031125-C00199.png) 1976-05-07
BG25230A3 (en) 1978-08-10
SE420202B (sv) 1981-09-21
AR199202A1 (es) 1974-08-14
IE37474L (en) 1973-09-30
PL91817B1 (US06653308-20031125-C00199.png) 1977-03-31
LU67317A1 (US06653308-20031125-C00199.png) 1973-06-08
ZA732180B (en) 1974-01-30
IE37475L (en) 1973-09-30
CH594009A5 (US06653308-20031125-C00199.png) 1977-12-30
DE2215539A1 (de) 1973-10-18
BR7302272D0 (pt) 1974-06-27
IL41885A0 (en) 1973-05-31
AT324998B (de) 1975-09-25
DD108099A5 (US06653308-20031125-C00199.png) 1974-09-05
EG10983A (en) 1976-10-31
FI52732B (US06653308-20031125-C00199.png) 1977-08-01
GB1413381A (en) 1975-11-12
FR2186479A1 (US06653308-20031125-C00199.png) 1974-01-11
NL7304330A (US06653308-20031125-C00199.png) 1973-10-02
ES413132A1 (es) 1976-01-16
CA1036746A (en) 1978-08-15
AT324264B (de) 1975-08-25
BG25232A3 (en) 1978-08-10
TR17150A (tr) 1974-04-25

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Legal Events

Date Code Title Description
OD Request for examination
8125 Change of the main classification

Ipc: C12N 11/00

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8364 No opposition during term of opposition
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